The Egg Freezing Trigger Shot: Your Complete Guide

If you're considering egg freezing or have already started the process, you've likely heard rumors about the "trigger shot." This important step in the egg freezing journey can, like much of the process, seem mysterious and perhaps a bit daunting. But don't worry – we're here to demystify the trigger shot and provide you with all the information you need to feel confident and prepared.

In this guide, we'll explore what the trigger shot is, why it's necessary, how it works, and what you can expect when it's time for you to take this important step in your egg freezing cycle. We'll also address common concerns, potential side effects, and tips for ensuring the best possible outcome.

What is the egg freezing trigger shot?

The trigger shot, also known as the "ovulation trigger" or simply "the trigger," is a hormonal medication given near the end of your egg freezing cycle. Its primary purpose is to mimic the natural surge of luteinizing hormone (LH) that occurs in your body just before ovulation. This surge signals your ovaries to complete the final maturation of the eggs and prepare them for retrieval.

In a normal menstrual cycle, this LH surge would lead to ovulation – the release of a mature egg from the ovary. However, in an egg freezing cycle, the trigger shot allows your doctor to precisely time the egg retrieval procedure, ensuring that your eggs are at the optimal stage of maturity for freezing.

What does the trigger shot do?

The trigger shot serves two important functions in the egg freezing process:

1. Final egg maturation: It prompts the final stage of egg maturation, ensuring that the eggs are ready for retrieval and freezing.
2. Timing control: It allows your fertility doctor to precisely schedule the egg retrieval procedure, typically 34-36 hours after the trigger shot is administered.

These two functions of the trigger shot work together to optimize the egg freezing process, helping to ensure the best possible outcome for preserving your fertility.

Is the trigger shot necessary?

In short, yes. The trigger shot is an important part of the egg freezing process. Without it, it would be extremely difficult to time the egg retrieval accurately, and the eggs might not be at the optimal stage of maturity for freezing. The trigger shot ensures that you get the best possible outcome from your egg freezing cycle.

Types of trigger shots

There are two main types of medications used for the trigger shot:

1. hCG (Human Chorionic Gonadotropin): Brands include Ovidrel, Pregnyl, and Novarel. This medication directly mimics the LH surge, and requires some mixing before administration.
2. GnRH Agonist: Brands include Lupron (also known as leuprolide acetate). This alternative trigger medication works by causing your body to release its own surge of LH.

Your doctor will decide which type of trigger shot is best for you based on your individual circumstances and how you've responded to the stimulation medications.

How is the trigger shot administered?

The trigger shot is typically given as a subcutaneous injection (into the fatty tissue just under the skin) or intramuscular injection (into the muscle). Your fertility clinic and/oor pharmacy will provide detailed instructions on how to administer the shot, which is usually done at home.

The timing of the trigger shot is very important. Your doctor will give you very specific instructions about when to take the shot, often down to the exact hour. It's essential to follow these instructions precisely to ensure the best outcome.

Is the trigger shot painful?

Most women report that the trigger shot is not particularly painful. The needle used for subcutaneous injections is very small, and while you might feel a slight pinch, any discomfort is usually brief. There are tactics you can use to make the injection less painful, like icing the area beforehand.

Read more in I'm Afraid of Needles; Can I Still Freeze My Eggs?

Common mistakes to avoid

While the trigger shot is straightforward, there are a few common mistakes to be aware of:

1. Timing errors: Administering the shot at the wrong time can significantly impact the success of your egg retrieval. Set alarms and double-check your instructions.
2. Incorrect dosage: Make sure you understand exactly how much medication to inject.
3. Wrong injection site: Follow your clinic's instructions carefully regarding where to administer the shot.
4. Forgetting to mix medications: Some trigger shots require mixing before injection. Make sure you understand the preparation process.
5. Not asking for help: If you're unsure about anything, don't hesitate to contact your clinic for clarification.

Potential side effects

Like all medications, the trigger shot can have side effects, although many women experience few or no side effects since it’s just one shot. Possible side effects may include:

• Injection site reactions: Redness, swelling, or mild pain at the injection site.
• Breast tenderness: Your breasts might feel swollen or sensitive.
• Feeling restless or irritable: Hormonal fluctuations can sometimes affect mood. .
• Headache: Some women report feeling headaches.
• Ovarian Hyperstimulation Syndrome (OHSS): In rare cases, the trigger shot can contribute to OHSS, a condition where the ovaries become swollen and painful. Your doctor will monitor you closely for signs of OHSS.

Most side effects, if they occur, are mild and resolve on their own. However, always inform your doctor of any side effects you experience. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

What to expect after the trigger shot

After administering the trigger shot, you'll likely be asked to abstain from sexual activity to prevent unintended pregnancy. You may notice some increased discomfort or bloating as your eggs complete their final maturation.

Your doctor will schedule your egg retrieval procedure for approximately 34-36 hours after the trigger shot. It's important to arrive on time for this appointment, as the timing is precise!

Tips for Success

To ensure the best possible outcome with your trigger shot:

• Follow instructions carefully: Pay close attention to your clinic's instructions regarding timing, dosage, and administration.
• Create a comfortable environment: Set up a clean, well-lit area for administering the shot.
• Stay calm: If you're nervous, try deep breathing exercises or ask a friend or partner for support.
• Be prepared: Gather all necessary supplies before starting.
• Track everything: Keep a log of when you administered the shot and any side effects you experience.
• Stay in touch with your clinic: Don't hesitate to reach out if you have any questions or concerns.

At this point in your egg freezing cycle, you are nearly finished! Celebrate how far you’ve come and start making plans to treat yourself after the cycle is over.

Frequently Asked Questions

• Can I exercise after the trigger shot? It's generally recommended to avoid strenuous exercise after the trigger shot. Light activities like walking are usually fine, but consult with your doctor for personalized advice.
• What if I miss the timing of the trigger shot? If you realize you've missed the scheduled time for your trigger shot, contact your clinic immediately. They will advise you on the best course of action.
• Can I travel after the trigger shot? It's best to avoid travel between the trigger shot and egg retrieval. The timing of the retrieval is crucial, and travel could potentially interfere.
• Will the trigger shot affect a pregnancy test? Yes, the hCG trigger shot can cause a false positive on a pregnancy test for up to 14 days after administration. If you need to take a pregnancy test during this time, inform your doctor about the trigger shot.
• What happens if the trigger shot doesn't work? While rare, if the trigger shot doesn't work effectively, your doctor might cancel the egg retrieval and adjust your protocol for a future cycle.

Final thoughts

The trigger shot is a huge step in your egg freezing journey. While it might seem intimidating at first, understanding its purpose and what to expect can help alleviate any anxiety. Remember, this shot is bringing you one step closer to increasing your fertility options for the future.

As with all aspects of egg freezing, the key to success with the trigger shot is clear communication with your clinic’s team. Don't hesitate to ask questions or voice concerns. Your clinic is there to support you every step of the way.

By following your fertility doctor's instructions carefully and staying informed, you're setting yourself up for the best possible outcome. The trigger shot is more than just another injection – it's the final step before your egg retrieval, bringing you to the culmination of your egg freezing cycle!

As you prepare for your trigger shot, take a moment to appreciate the journey you're on. Egg freezing is a proactive step towards taking control of your reproductive future, and each step of the process, including the trigger shot, is a part of that empowering decision.