egg quality
Can You Really Measure How Many Eggs You Have?
Can you truly measure how many eggs you have? Let's delve into the world of ovarian reserve testing and explore the possibilities and limitations.
In the world of reproductive health and fertility, there is a growing interest in understanding the quantity of eggs a woman has, also known as ovarian reserve. The concept of measuring ovarian reserve has gained popularity as more people seek to assess their fertility potential and make informed decisions about family planning.
But can you truly measure how many eggs you have? Let's delve into the world of ovarian reserve testing and explore the possibilities and limitations.
How many eggs do females have?
Females are born with approximately one to two million oocytes, and it only goes down from here since no new eggs are made. But here's where it gets interesting.
Once we reach puberty, a process triggered by a complex interplay of hormones, only about 300,000 of these oocytes will remain. These precious few will have the opportunity to mature and potentially be released as eggs during our reproductive years. Our bodies typically release just one egg per menstrual cycle, and this process occurs approximately 400 times throughout our lifetime.
These remaining oocytes are not merely passive bystanders. Each one resides within a protective structure called a follicle, where it lies dormant and suspended in the middle of a cell division. Remarkably, the lifespan of an egg is one of the longest among the body's cells. However, this extended duration can also increase the chances of damage and genetic abnormalities as we age.
At menopause, which is defined as one year after your last menstrual period, the pool of remaining oocytes steadily declines until none remain. This natural process signifies the end of our reproductive years.
Understanding the intricacies of egg development and the limited supply available underscores the importance of considering fertility and family planning at an earlier age. Each egg is a precious resource, and its quality and viability can impact the chances of achieving a successful pregnancy. Exploring fertility preservation options, such as egg freezing, can provide women with greater control over their reproductive future.
While the numbers presented here provide a general understanding, it's crucial to remember that everyone’s ovarian reserve is unique. Factors like genetics, lifestyle, and overall health can influence the rate of egg loss and fertility potential.
Egg count and age
As stated above, females are born with one to two million eggs. By puberty, only about 300,000 of these oocytes will remain. After starting the menstrual cycle, we lose about 1,000 immature eggs every month… meaning by age 37 there are around 25,000 eggs remaining. And by menopause, no more eggs remain.
Here is a rough chart of what this could look like for an individual. Keep in mind that everyone starts with a different number of eggs, and everyone’s rate of decline varies. This chart is just to give you an idea of what this egg count could look like:
Measuring egg reserve (aka ovarian reserve)
Ovarian reserve refers to the number of eggs remaining in a woman's ovaries at a given time. It is one indicator of a woman's reproductive health, and can help guide fertility treatment decisions. The idea of quantifying ovarian reserve has gained significance as women strive to gain insights into their fertility and make proactive choices about their reproductive journey. And at the same time, at-home tests make it easier to measure your ovarian reserve.
Keep in mind that the number of eggs you have does not necessarily equate to your ability to conceive. Other factors, such as egg quality, the presence of any reproductive disorders, and the overall health of the reproductive system, play significant roles in fertility. Not to mention the health of the sperm! Some people have lower ovarian reserve but still achieve successful pregnancies, while others with a seemingly healthy ovarian reserve may face challenges in conceiving.
How to measure ovarian reserve
One of the most commonly used methods to measure ovarian reserve is through a blood test that evaluates specific hormone levels. These hormones include anti-Müllerian hormone (AMH), follicle-stimulating hormone (FSH), and estradiol. AMH, in particular, has emerged as a reliable marker of ovarian reserve, as it reflects the number of small follicles in the ovaries that contain immature eggs. Low levels of AMH may indicate a diminished ovarian reserve, while higher levels may suggest a larger pool of eggs.
While ovarian reserve testing provides valuable insights, it is not a crystal ball that can predict fertility outcomes with absolute certainty. Ovarian reserve is just one piece of the fertility puzzle, and other factors such as egg quality, uterine health, and sperm quality also play crucial roles in the conception process. Additionally, fertility is influenced by various external factors, including age, lifestyle, and underlying health conditions.
Fertility testing can provide a snapshot of ovarian reserve at a specific moment in time. Ovarian reserve naturally declines with age, and the number of eggs available for fertilization decreases over time. Therefore, it's crucial to interpret the results in the context of your age and overall health.
Egg reserve testing methods
Another consideration when evaluating ovarian reserve is the variation in testing methods and reference ranges used by different laboratories. Each laboratory may have its own set of standards and measurements, which can lead to variations in results. You may want to consult with a fertility doctor who is knowledgeable in reproductive medicine to interpret the test results accurately and provide personalized guidance (if you work with Cofertility, we can help you set this up).
So, can you measure exactly how many eggs you have?
While ovarian reserve testing can provide valuable information, determining the exact number of eggs a woman has remaining in the ovaries is not possible.
Why? First of all, the number of eggs in the ovaries is not static but rather dynamic and constantly changing. We are born with a finite number of eggs, and this number gradually declines over time through a process called follicular atresia. This natural process of egg loss occurs throughout our reproductive years, and the rate of decline varies from person to person.
Second, the accuracy of measuring the exact number of eggs is hindered by the limitations of current medical technology. While imaging techniques like ultrasound can visualize the presence of ovarian follicles, they cannot precisely determine the number of eggs within each follicle. Additionally, even if the number of follicles can be counted, it does not equate to the exact number of eggs, as not all follicles contain a viable egg.
Ovarian reserve is just one piece of the puzzle
While ovarian reserve testing can provide valuable information, it is just one tool in the broader landscape of fertility assessment. A fertility doctor can consider your medical history, conduct a physical examination, measure your antral follicle count, and may recommend additional tests or imaging studies to provide a comprehensive assessment of your reproductive potential.
Cofertility is a human-first fertility ecosystem rewriting the egg freezing experience. With our Freeze by Co platform, women can freeze their eggs for free when they donate half of the retrieved eggs to a family who can’t otherwise conceive. We are obsessed with improving the family-building journey — today or in the future — and are in an endless pursuit to make these experiences more positive.
Should I Freeze Eggs or Embryos?
More people than ever are thinking about preserving their fertility for the future. But what’s the difference between freezing eggs and freezing embryos? More importantly, which is the better option for you?
More people than ever are thinking about preserving their fertility for the future. But what’s the difference between freezing eggs and freezing embryos? More importantly, which is the better option for you?
While both procedures have given people more choice around when they have children and how they conceive them, they’re not the same and there’s plenty to think about when trying to choose one over the other.
What’s the difference?
There’s one major difference between freezing eggs and freezing embryos. When you freeze your eggs, they stay unfertilized. We all know that to make a baby, you need an egg and a sperm because each of them provides half of the material needed. On its own, an egg can’t function (and neither can a sperm).
An embryo, on the other hand, is an egg that has already been fertilized by a sperm. Once they combine, the egg and sperm become a single cell. Over the next three to four days, the embryo divides several times, going from one to two to four to eight cells, and so on until it reaches the blastocyst stage and is ready to be frozen. Once an embryo has developed, there’s no going back– that is, there’s no way to turn that embryo back into a separate egg and sperm.
Things to consider
So how does this information help you figure out whether to freeze eggs or embryos? Well, there are two big factors to consider: your circumstances and the research.
If you don’t know who you want to have children with, then freezing your eggs may be the best approach. This option gives you the freedom to hold off on thinking about having a baby until you’ve met someone or are ready to choose a sperm donor.
On the other hand, if you are currently with a partner who you know you’d like to have children with but now isn’t the right time, then freezing embryos might be the way to go. The caveat here is to be 100% certain—stars like Sofia Vergara and more recently, Anna Kendrick, have run into trouble after freezing embryos with partners they didn’t end up with.
Now, let’s look at the research.
Is freezing embryos really better?
The short answer here is not necessarily. The long answer is that each case is unique so whether freezing embryos or eggs is the better option for you will depend on your specific situation and what your labs, imaging, and other health information suggest.
With that in mind, let’s break down the pros and cons of each method.
Pros and cons of freezing eggs vs embryos
Freezing/thawing process
Historically, embryos have been “tougher” than eggs and therefore, easier to freeze and thaw. Freezing eggs was much more of a gamble since they’re large cells with a lot of water inside. That water can turn into ice crystals during freezing which, in turn, can damage the chromosomes in the eggs and make them unusable.
But it’s not all gloom and doom for egg freezers! Researchers have continued to study the technology and the statistics have changed as newer and better freezing technologies have emerged. Nowadays, an excellent lab can expect 97% of the eggs that they freeze to survive compared to 95% for embryos.
But, let’s be clear, these numbers don’t mean that your chances of a successful live birth are 3% higher with frozen eggs, it just means that they are a little more likely to make it to the next phase of IVF. The higher the quality of your frozen eggs (i.e. if you freeze your eggs relatively young and maintain a healthy lifestyle), the more likely they will have thaw rates that are just as good (if not higher) than that of embryos.
Quality
A major weakness of egg freezing is that there is no way to test the quality of eggs on their own–they still have to make it through the thawing process, fertilization, and develop into a healthy embryo that can be implanted into the uterus (not all of them make it this far).
This can lead to a situation where someone uses their eggs years after freezing them and those eggs don’t perform as well as they thought they would. By then, this person is older so their egg quality has declined even more. Not having that quality information upfront can make it hard to judge how many eggs need to be frozen to lead to an actual baby.
In contrast, embryos have to get past several important hurdles that give fertility specialists a much better sense of their quality and the chances of a baby later. That’s because turning eggs into embryos requires that they be successfully fertilized and that those embryos survive up to a point where they can be frozen (usually the blastocyst stage, around day 5 of development).
In addition, embryos are graded at each point in their development based on an embryologist’s opinion of whether they are high quality or not (embryologists are experts who study the development of embryos).
Finally, you have the option to run a genetic screening test on embryos, which can help more accurately predict whether they’re likely to become healthy babies. Research has shown that preimplantation genetic screening can result in lower miscarriage rates and higher live birth rates per embryo transfer. There is no such test for frozen eggs.
Chances of a healthy baby down the line
Recent studies comparing the likelihood of actual babies being born, known as the live birth rate (LBR), have shown that it’s now pretty even whether you’re freezing eggs or embryos. Before this, the LBR with frozen eggs was quoted at about 50% the LBR of frozen embryos.
A study published in May 2022 provides even more evidence to support this. The study, done at NYU, is the largest U.S. report of elective fertility preservation outcomes to date and is based on 15 years of real-life frozen egg thaw outcomes for people who had delayed having children and had natural, age-related fertility decline.
On average, study participants were 38 years old at the time they froze their first set of eggs. The study found that regardless of age, those who thawed at least 20 mature eggs had a 58% LBR. This was unexpected given that so many of the participants were past the optimal age to freeze eggs (35 years old or younger). People under 38 years old who thawed 20 or more mature eggs had a 70% LBR per patient. The length of frozen egg storage did not change the success rate.
Additionally, the study found that 39% of people between 27 and 44 years old (most were between 35 and 40 when they froze their eggs) had at least one child from their frozen eggs, which is comparable with age-matched in vitro fertilization (IVF) outcomes. Researchers also found that many of the participants studied had more than one child through egg freezing.
When compared to data collected by the Centers for Disease Control and Prevention (CDC) from the nation’s nearly 500 fertility clinics on people trying to conceive at age 40 using fresh eggs or embryos, only 30% who underwent IVF became pregnant and the LBR was less than 20%.
The final conclusion? For those starting families later, egg freezing and thawing at a later date provides a higher pregnancy success rate than using fresh embryos during assisted reproductive technology.
*One important point the researchers make about their study is that it was limited by the number of patients. More studies need to be done in the future that include people from a variety of geographic locations and center types.
Cost
Last, but certainly not least, is the financial side of this. Is embryo freezing more expensive than egg freezing?
Honestly, yes. The upfront cost of egg freezing is definitely less than that of embryo freezing (which requires in vitro fertilization before freezing). While egg freezing costs upward of $10,000 on average, creating and freezing embryos can add a few more thousand dollars to that bill. If you’re freezing embryos using a sperm donor, the sperm can add a further $300 to $4,000, depending on several factors. In both cases, you will also need to pay an annual fee to store your eggs or embryos until you use them. This can cost anywhere from $500-$1000 per year, depending on the clinic you use.
Depending on the type of medical coverage you have, your insurance may cover some of these costs, so make sure you reach out and see what support you can receive from them. Many clinics also offer financial plans and other forms of support so always ask!
TL;DR: Freezing eggs comes with a lower upfront price tag which makes it an easier and more accessible choice than embryo freezing, allowing more people to preserve their future options.
Additional Resources
Both the Centers for Disease Control & Prevention (CDC) and experts at Harvard Brigham and Women’s Hospital have developed calculators for assessing a person’s chances of success with artificial reproductive technology (ART). The CDC IVF Success Estimator helps estimate the chances of a live birth with IVF while the BWH Egg Freezing Counseling Tool helps to estimate the chances of at least 1 live birth based on your age and number of frozen eggs.
What do I ask my provider?
Use your health care provider as a support and resource. They should be able to answer any of your questions. Not sure what to ask? Here are a few questions to help you get started:
- How many eggs or embryos do you recommend I freeze, at my current age, to have the highest percentage chance of a live birth later on?
- How many treatment cycles will I need to do to get to this number? It’s totally normal to need more than 1 cycle, but it’s nice to know what to expect ahead of time.
- What is this lab’s rate of successful freezing and thawing of eggs vs embryos (“oocyte cryosurvival rate” is the medical term)? Are they closer to minimal or maximum competency?
- How much would each cycle cost?
- Are there any financial support options, plans, or advice?
- What are the health risks? What about common side effects?
- Is there an upper age limit for using my eggs or embryos in the future?
- How long can I store them and how much will it cost per year?
Do You!
At the end of the day, there’s no universal rule around the best approach to preserving fertility. Family planning is going to look different for every person so you need to do what’s right for you. When you’re ready, talking to a fertility specialist can help you make up your mind.
In the meantime, Freeze by Co is here to help you every step of the way on that journey. Our Split program allows those who qualify to freeze their eggs for free! In a “Split” cycle, you donate half of the eggs retrieved to a family that’s trying to conceive and freeze the remaining half for yourself. Or, if you don’t want to donate, you can still participate in the Keep program, where you’re able to freeze your eggs and keep them all for yourself, on your timeline. In addition, you’ll have access to our online support community. This valuable resource lets you engage with other people freezing their eggs at the same time!
Whatever you end up choosing for yourself, our team is here to guide you through it and keep your options open.
How Many Eggs Should I Aim to Freeze?
You might have heard that freezing your eggs can help you preserve your fertility options for your long term future. We're breaking down all of the factors involved with egg freezing for fertility preservation.
You might have heard at some point that freezing your eggs can help you preserve your fertility options for your long term future. But just how many eggs should you freeze? Is there an optimal number for egg freezing?
Let’s take a look at how many eggs you can expect to get during the retrieval process and how many eggs you should be freezing for fertility preservation.
How many eggs do I have?
Before we talk about the number of eggs you should freeze during oocyte cryopreservation — more commonly known as freezing your eggs — we should probably talk about how many eggs are in your ovaries right now.
Your fertility doctor may have mentioned the term ovarian reserve a few times. When they do that, they’re talking about the number of eggs in your body. But how many eggs are in that reserve?
There is no exact answer here. On average, women are born with anywhere from one to two million eggs. Some women are born with more. Some women are born with less.
It may sound like a lot either way, but most of the eggs we’re born with don’t stick around. By the time most of us hit adolescence,we have about 300,000 eggs left. From there, the number of eggs in the body naturally decreases by about 1,000 every year, and the decline becomes more rapid after age 35.
That’s where egg freezing comes into play. The doctors of the Association of Reproductive Medicine (ASRM) states that planned oocyte preservation is “ethically permissible” because it provides women with more autonomy over their reproductive choices.
Doctors can get a sense of how large your ovarian reserve is before egg freezing by testing the level of the anti-Müllerian hormone (AMH) in your body. This test looks at both your ovarian reserve and how well your body may or may not respond to medications that will stimulate the ovaries. What it can’t determine, however, is the quality of those eggs. And ultimately, you need both quantity and quality.
How many eggs do I need to freeze?
OK, so you may have a lot of eggs in your ovarian reserve — or maybe not. But how many do you actually need to freeze?
This answer varies from person to person and depends on a few individual factors:
- How old are you right now?
- Do you plan to freeze all of your eggs or do you hope to also donate some to help intended parents grow their family?
- If you think you may want to have children one day, how many do you have in mind?
This list presents a lot to think about, so let’s dive a little deeper to help you make informed decisions about the number of eggs you freeze.
The right number of eggs to freeze for your age
Different folks have different reasons for freezing their eggs. Some may be thinking about prolonging their fertility into the future. Others may be freezing some eggs but also hoping to donate some eggs to help others grow a family — something that’s done via our Split program, where you freeze for free when donating half of the eggs to a family that can’t otherwise conceive.
Either way, studies have found that the optimal number of eggs to freeze really comes down to your age. That’s because the number of eggs in the body isn’t the only thing to decrease as you get older — egg quality decreases too, and egg quality is the number one factor in determining whether an egg can eventually result in a live birth.
Here are the number of eggs you’ll want to freeze based on your age in order to obtain an optimal live birth rate:
How many eggs are retrieved?
For egg donors aged 25-29, the average number of eggs retrieved is 18, and that number drops to 16 for people age 30-35 — although it varies from person to person.
Your reproductive endocrinologist will be able to tell you the day of your retrieval how many eggs were retrieved. This number will include both mature and immature eggs, so it’s not necessarily the total number of eggs that can be frozen.
Immature Eggs
- May be partially or completely damaged or have its quality compromised in some way
- Lower chance of fertilization
Mature Eggs
- Have good egg quality
- Are more likely to be fertilized
- Can be frozen
After your retrieval, all of your eggs will be sent to an incubator to check maturity. The lab technicians will look for eggs to achieve meiosis, a kind of cell division that occurs in egg cells.
The eggs that achieve meiosis will be frozen, and you will be notified of the total number.
Should I do multiple egg retrievals?
What happens if you don’t get as many eggs as you had hoped during your egg retrieval cycle?
If you’ve undergone one round of egg freezing and the number of eggs your reproductive endocrinologist retrieved from your ovaries wasn’t as high as you’d hoped, you may want to talk to them about trying again.
There is technically no limit to the number of egg freezing rounds a person can undergo, but it’s not recommended that egg donors undergo more than six cycles. If you’re hoping to split your eggs with intended parents (donating half of the eggs retrieved) as part of our Split Program, you may find that additional retrievals help you provide the optimal amount of eggs for a live birth for you and for the intentend parents too.
Of course, you should talk to your doctor about any risks or benefits that come with additional rounds.
The right number of eggs to freeze to have multiple children
If you’re planning to have a big family one day, you may want to look at the number of eggs it’s recommended you freeze to achieve one live birth and talk to your doctor about freezing more eggs.
For example, the studies show that a woman under age 35 will need to freeze about nine eggs to achieve a 70% chance of a live birth. If you’re under age 35 now and thinking you might want to use frozen eggs to conceive twice in your future, you will want to freeze closer to 18 eggs to achieve that 70% chance each time.
That number will increase with each number of children you foresee — provided your expectation is that each child will be conceived with the use of the eggs you are currently freezing.
Bottom line
There is no “magic number” when it comes to freezing your eggs. Your age, your future plans, and more all come into play.
We’re here to answer any questions you might have, and the Cofertility community is also here to lend support as you consider all the important factors to make the choice that is right for you.
Why Do Female Physicians Face a Higher Rate of Infertility?
If you’re a female physician in the United States, you may have heard that you’re at a higher risk of infertility. Read on for the research into this fertility concern and what American doctors are doing about it.
If you’re a female physician in the United States, you may have heard that you’re at a higher risk of infertility than your female friends who took a different career path. It certainly sounds like the kind of “fact’ that gets posted on social media one day and suddenly becomes gospel, whether it’s true or not.
Unfortunately, we can’t just write this one off as a social media hoax. Researchers have run the numbers, and it turns out almost 25% of female doctors who are trying to conceive are faced with fertility challenges. This is about double the rate of the general public.
“It turns out almost 25% of female doctors who are trying to conceive are faced with fertility challenges. This is about double the rate of the general public. “
So what’s going on? Should you be freezing your eggs now just in case? Is there anything else you can do? Read on for the research into this fertility concern and what American doctors are doing about it.
Female doctors and fertility
General fertility rates have been trending downward in the US in recent decades with the CDC reporting record low birth rates in 2018 and only minimal increases since. In 2021, the American birth rate was 1,663 births per 1,000 women — not enough to maintain stable population figures in the US.
And while some of that could be due to personal choice, scientists have found increasing rates of reproductive problems are cropping up in women and men. Miscarriage rates are up about one % every year and so are the rates of gestational surrogacy — an option growing in popularity for intended parents seeking the help of an additional party for conception.
But the plight of female doctors stands out among all these figures:
- 1 in 4 — The approximate number of female physicians who were diagnosed with infertility after trying to have a baby, according to a survey published in the Journal of Women’s Health in 2016
- 11 % — The percentage of American women in the general population have had the same diagnosis.
- 42 % —The amount of female surgeons who have experienced a pregnancy loss, according to a survey published in JAMA Surgery in July 2021 which reported that 42 % had experienced a pregnancy loss.
What’s going on?
What makes female doctors so different from the rest of the population? In part, their education.
There’s no real way to put this nicely: Age matters when it comes to fertility. Extensive medical research on fertility shows that getting older has a major effect on our reproduction system and our ability to conceive.
But many female doctors — surgeons included — delay pregnancy until after the completion of their residency. How long that will take depends on the doctor’s specialty, but this can be another three to eight years after medical school. For surgeons, a residency is a minimum of five years.
That puts many female doctors into their 30s before they even begin trying to have their first child. In fact, in the 2016 survey, doctors reported they were 31.6 year old on average at completion of medical school and residency and 30.4 years on average at first pregnancy. By comparison, the average age of an American woman giving birth for the first time in the US is 26 years old, according to data compiled for the New York Times in 2018.
Almost a third — 28% — of the female doctors surveyed in 2016 who experienced fertility challenges said they would have begun trying to conceive earlier if they could have seen what lay ahead. Close to the same number — 29% — said they experienced diminished ovarian reserve, a condition in which their fertility challenge was linked to having fewer eggs in the body. This condition is largely associated with age.
But delaying reproduction is only part of the puzzle.
Even after adjusting for age, female physicians have higher rates of infertility. Perhaps this is due to female doctors facing high rates of stress at work that put a strain on the body and can affect reproduction as a whole. Those who opt to start a family before residency is complete may face irregular work schedules and long, grueling shifts that can put intense strain on anyone’s body, but prove especially hard for someone who is pregnant.
Together, all of these factors can have a significant impact on the fertility of a female doctor.
How can female doctors preserve their fertility?
The numbers may seem a little daunting, especially if you’re in medical school or the midst of your residency. So what can women do about it?
An infertility task force now exists as part of the American Medical Women’s Association to find answers to this problem plaguing women in medicine, and individual doctors around the country have been working to advocate for improved fertility education and fertility insurance coverage for their peers.
One of the chief criticisms of the current system comes from Dr. Areila Marshall, one of the founders of the AMWA task force, who wrote about the issue in the journal Academic Medicine in 2020 calling for better awareness of egg, embryo, and sperm cryopreservation.
Marshall echoed a wish expressed by a number of the physicians who took part in the original 2016 survey: 7% of those doctors said they wished they had known to use cryopreservation to extend their fertility.
For female doctors who don’t know when — or even if — they want to conceive, egg freezing can be a viable option.
Freezing is not a guarantee that you will have a baby down the line. It simply means that eggs will be there, waiting, if you decide at some point in the future that you wish to explore conception.
At Freeze by Co, we are committed to giving women the opportunity to have more control over their reproductive choices. Here women have a variety of paths they can choose from when it comes to egg freezing – whether they’re looking to freeze eggs now or have already frozen some of their eggs.
Members of our Split program even freeze for free when they give half of their eggs to intended parents who cannot otherwise conceive.
Bottom line
Women should not have to choose between a dream of pursuing a career in medicine and making reproductive decisions on their own timeline. Egg freezing gives women the power to make more choices about her own body.
A Breakdown of Egg Freezing Success Rates by Age
You may have heard that freezing your eggs in your 20s can help increase your chances of pregnancy down the line, but is there actually any truth to the claim? Read on to learn what you need to know about egg freezing success rates by age.
You may have heard that freezing your eggs in your 20s can help increase your chances of pregnancy down the line, but is there actually any truth to the claim? According to the American College of Obstetrics and Gynecologists (ACOG), there really is, given a woman’s peak fertility years span from the end of her teens to the end of her 20s.
Read on to learn what you need to know about egg freezing success rates by age.
The best time to think about egg freezing is probably…now
During these prime fertility years, we’re often focused on other things. In our 20s, we’re finishing school, launching our careers, traveling, having fun…starting a family may not even be a blip on your radar. Unfortunately, that also means that by the time you’re ready to get proactive about your fertility (or starting a family), your prime reproductive years may have already passed.
This is why we believe that proactively thinking about your fertility is always a good idea for anyone looking to stay in control of their reproductive options. And one major barrier, until now, has been the accessibility and affordability of egg freezing. At Cofertility, we aim to change that, by partnering with local fertility clinics to create opportunities to freeze your eggs more affordably.
Take our quiz to see what egg freezing options you may qualify for, including our Split program, where you can even freeze your eggs for free(!) if you give half to a family that can’t otherwise conceive and you qualify.
What are the egg freezing success rates by age?
We measure the “success” of an egg retrieval and later vitrification (the process of freezing and storing your eggs) in a couple of ways. Some of the major important milestones in a successful retrieval are:
- The ability to collect high quality and healthy eggs
- The ability to collect a large, but safe, number of eggs during a single cycle (between 10-20 is ideal)
- Whether collection takes place at an age where the eggs have a very good chance of surviving both the freezing and the warming process down the line
Success rates for women in their 20s
Your 20s are by and large the best time to freeze your eggs, with 25 to 27 being the optimal age, according to a 2010 report from the CDC. The report found that eggs frozen during a woman’s 20s will have a 50 percent chance of resulting in a live birth per cycle, regardless of the age of the person carrying the pregnancy once the eggs are used. Women in this age range have fully finished developing (as opposed to someone in their late teens or early 20s who may still be growing and maturing) and are likely to have the healthiest and most robust eggs.
Not only does it make it easier for eggs collected at this age to go on to become successful pregnancies, but it also makes it the most cost effective period, because you’re likely to get more eggs with fewer rounds of freezing than if your eggs were collected at a later age.
Success rates for women in their 30s
Success rates in your 30s will depend on if you’re closer to 30 or 40, as well as your AMH levels. One study of 1,241 women found that the average number of eggs retrieved on the first egg freezing round was:
- 21 eggs for women under 35
- 17 eggs for women 35-37
- 14 eggs for women 38-40
Because women in their 30s tend to produce less eggs, at this age you may end up having to either settle for fewer eggs for freezing or undergo multiple rounds to collect enough eggs to have on hand for later implantation. As you can imagine, those costs can creep higher and higher the more rounds you endure.
Now, you might be thinking: isn’t 14 eggs a lot? It’s true that eggs retrieved from women under the age of 36 will have a 95 percent survival rate after being thawed.
But more importantly, not all thawed eggs will become viable embryos and lead to a live birth. As this chart underscores, the probability of a live birth varies with the age of the woman trying to conceive and the number of mature eggs available. In short, the older the woman, the more eggs required to achieve a high probability of a live birth.
A study in the Journal of Assisted Reproduction and Genetics further supports this point. For example, a woman under 35 will need 9 eggs to achieve a 70% chance of having at least one live birth. If you’re trying to conceive in your mid to late 30s, you may need double as many eggs to achieve that same 70% success rate.
Success rates for women in their 40s
Because success rates drop significantly as you near the end of your 30s, it’s actually not recommended that women have their eggs frozen past the age of 38, according to the American Society for Reproductive Medicine (ASRM).
But don’t let that news worry you. If you haven’t had your own eggs retrieved by this point, and are struggling to conceive, you still have some other options (including the use of donated eggs).
Ask us anything
If you’d like help figuring out when to freeze your eggs, you can contact Cofertility for more information. While every woman’s fertility path differs, we can connect you with reputable clinics who can offer basic guidance about when the time is right for you to freeze your eggs during a consultation or dig into specifics by going through a preliminary exam in a provider’s office.
We understand that the timing may not be right for you to start a family right now, but that doesn’t mean it’s too early to start thinking about what choices will be available to you when that time comes. As you can see, a lot goes into preparing to freeze your eggs. The earlier you consider your fertility, the more options you’ll have.
Whether you decide to freeze or not, we’re here for you to answer any questions or talk through any concerns.
A Step-by-Step Guide to Freezing Your Eggs
Egg freezing allows you to preserve your healthy eggs at any point in time, without committing to starting a family. Let's talk about what you need to know about freezing your eggs.
According to the American College of Obstetrics and Gynecologists (ACOG), a woman’s peak fertility years are from their late teens to their late 20s. While these may be the easiest biological years for starting a family, between travel, work, school, life…at that point in your life, family planning might not be your top priority.
Fortunately, thanks to modern medicine, you have some options. Egg freezing allows you to preserve your healthy eggs at any point in time, without committing to starting a family. Let's talk about what you need to know about freezing your eggs.
Here’s what you need to know about the process
While there are some big hurdles to clear—like the expenses of going through the process and how (and where) you’ll store your eggs—freezing your eggs is a way to take more control of your future fertility health.
That being said, it’s important that you think of freezing your eggs not as a guarantee, but rather, a proactive step you can take towards fulfilling potential long-term family planning goals. It is not an insurance policy, but it can help give you more options in the future.
Research has found that freezing nine eggs while under age 35 leads to a 70% chance of a live birth (studies found that the average number of eggs retrieved for the same women is 18-21). And the more eggs you freeze, the better those odds get. There are always chances that your retrieval could fail, or that implantation down the line may not take. Still, egg freezing in your 20s does offer higher chances of success than having them retrieved at a later age.
Getting ready for retrieval
Before you can freeze your eggs, you’ll want to ensure your body is producing as many eggs as possible. This means taking hormones that can help stimulate the follicles on your ovaries to produce a larger than normal quantity of eggs.
According to the Mayo Clinic, this may include taking multiple medications or injectables like:
- Ollitropin alfa or beta (Follistim AQ, Gonal-f)
- Menotropins (Menopur)
- Leuprolide acetate (Lupron Depot)
- Cetrorelix (Cetrotide)
- hCG
Your doctor will monitor your progress with blood tests across the 10-14 day period. He or she will tweak any ovarian-stimulating medications you’re given to make sure your estrogen and progesterone levels are where they need to be for a successful retrieval.
During these visits, you’ll likely also have vaginal ultrasounds. The doctor will use this to check on the development of the follicles where your eggs mature. It might sound overwhelming, but vaginal ultrasounds are usually painless.
Then, when the time is right—typically 10 to 14 days after you’ve started your medications—you’ll check back in with your doctor and receive a final injection of something called a human chorionic gonadotropin. This is the final kick to help your eggs mature and prepare them for retrieval.
Retrieving your eggs
Retrieval is typically done while you’re under a light sedation at a fertility clinic. Your doctor will retrieve your eggs via vaginal ultrasound with suction to remove eggs from follicles. You’ll likely wake up feeling well rested while your medical team has done all of the heavy lifting for you!
While you won’t feel any pain during the procedure, a little soreness afterwards isn’t uncommon.
Freezing and monitoring
After your procedure your eggs undergo a process called vitrification (AKA: freezing). This process relies on subzero temperatures to cool the eggs for storage. They’re normally stored along with a substance (like liquid nitrogen) that keeps ice crystals from forming within the frozen eggs. They’re then placed in cold storage for 24/7 temperature monitoring.
Storage timelines
You may be surprised to learn that your frozen eggs have no expiration date. In fact, in 2021 a child was born from an embryo frozen 25 years prior! Once your eggs have been successfully frozen they cease all biological activity, including aging and deterioration.
While some countries may have limits on the length of time your eggs can remain frozen, this has not taken hold in the United States. This comes as good news for women who are hoping to freeze their eggs earlier in life and may need more years of frozen storage.
Our Split program includes 10 years of free storage at a reputable long-term facility, where you'll have access to them whenever you choose to use them. Our Keep program also allows you to store your eggs for 10+ years, though note that the payment will be out of pocket each year.
How much does it cost?
A lot of women worry about the price tag for freezing their eggs. One piece of good news is that as technology (and availability) of these solutions advances, costs are starting to come down.
Still, you can be looking at a bill for a few thousand dollars for the procedure alone—anywhere between $6,000 to $11,000—plus an annual bill between $300-$1,200 for storage, and up to $5,000 for medications.
With Cofertility, however, we’ve worked with clinic partners to get you discounts on freezing (think: 75% off initial consults at certain clinics), storage (up to 80% off compared to reputable clinic freezing), and medications (about a 20% savings).
For those who qualify, our Split program also offers the opportunity to freeze your eggs for free if you donate half of them to a family who can’t otherwise conceive. Yep, zero dollars.
Split allows you to take control of your reproductive future (while offsetting the costs), and enables you to give someone else the greatest gift of all: a shot at parenthood. But at the end of the day, our mission is to empower women with reproductive choice. If you decide that freezing isn’t for you, we respect that. And most of all, we applaud you for taking this step towards exploring your options and learning more about your own fertility.
Can You Vape During Egg Freezing?
One area of concern is the impact of vaping on fertility, especially for those who are considering freezing their eggs for future use. In this article, we’ll dive into the research on if vaping is okay for egg freezing and donation.
Vaping has become a popular alternative to traditional smoking in recent years. But while it’s been marketed as a healthier option, the long-term effects of vaping are still not fully understood. One area of concern is the impact of vaping on fertility, especially for those who are considering freezing their eggs for future use. In this article, we’ll dive into the research on if vaping is okay for egg freezing and donation.
Impact of vaping on fertility
Several studies have found that vaping can have negative effects on reproductive health, including decreased fertility and increased risk of miscarriage. According to the American Society of Reproductive Medicine (ASRM), infertility rates in male and female smokers are twice as high as infertility rates among nonsmokers, with infertility rates rising with the number of cigarettes smoked daily. The main ingredients in e-cigarette liquids, such as nicotine and propylene glycol, have been shown to have toxic effects on the ovaries and the eggs they contain.
Nicotine has been shown to reduce the quality and quantity of eggs in the ovaries. It can also lead to decreased blood flow to the ovaries, which can negatively impact the development of the follicles, the structures in the ovaries that contain the eggs. Despite needing more medication during the egg freezing process, smokers often have fewer eggs available for retrieval during an egg freezing cycle, as well as 30% lower pregnancy rates compared with nonsmokers.
Propylene glycol, another common ingredient in e-cigarette liquids, has been shown to have a toxic effect on the ovaries and eggs. The same study has linked propylene glycol to oxidative stress, which can lead to damage to the eggs and decreased fertility. In addition, propylene glycol has been shown to cause DNA damage, which can affect the quality of the eggs.
How vaping may affect egg freezing outcomes
Egg freezing is a process where a woman's eggs are retrieved, frozen, and stored for later use once she is ready to fertilize them and start or grow her family. The more eggs that are retrieved, the better the chances of a live birth down the line.
While the effects of vaping on fertility are still largely unknown, many fertility clinics advise their patients to quit vaping in an effort to improve egg freezing outcomes related to quality and quantity based on the above research on smoking. Lower quality eggs with a higher DNA damage rate could impact the success of a future pregnancy using these frozen eggs, as these eggs may be less likely to fertilize into embryos (or result in a successful implantation). In addition, fewer eggs retrieved from those who vaped may result in fewer options for future use, which can increase the likelihood of needing additional egg freezing cycles.
Our programs offer the opportunity to freeze your eggs in a way that’s more empowering, positive, and affordable — even free. Take our quiz today to see if you qualify for Split, our free egg freezing program.
Can I donate my eggs if I vape?
If you are considering applying for our Split program, where you can freeze your eggs for free when you donate half of the eggs retrieved to another family, please note that you will not be considered eligible if you currently use any nicotine products, including vaping. If you engage in vaping regularly, you will need to quit for two to three months before re-applying for the program. If you only vape occasionally/socially, you will need to quit for one month prior to your retrieval date.
Summing it up
In conclusion, while data is somewhat limited, it appears that the effects of vaping on fertility can have an impact on women who are considering egg freezing. The ingredients in e-cigarette liquids, such as nicotine and propylene glycol, have been shown to have negative effects on reproductive health, including decreased fertilization rates and increased risk of miscarriage. In addition, it is possible that vaping can lead to a lower number of eggs retrieved during an egg freezing cycle and a higher rate of DNA damage in the retrieved eggs.
Our recommendation? Safe is better than sorry — in the interest of the best cycle outcome, it’s probably a good idea to hold off on the e-cigarettes leading up to and during your egg retrieval.
If you’re considering egg freezing, consult with a fertility specialist or take our quiz to learn more about how you can preserve your fertility.
What Does a High AMH Result Mean?
Anti-Mullerian hormone (AMH) is a hormone produced by ovarian follicles. It is commonly used as a marker of ovarian reserve and can be measured in the blood. A high AMH level is often associated with polycystic ovary syndrome (PCOS), but it can also have other causes. In this article, we will explore what a high AMH result means and answer some common questions about AMH testing.
Anti-Mullerian hormone (AMH) is a hormone produced by ovarian follicles. It is commonly used as a marker of ovarian reserve and can be measured in the blood. A high AMH level is often associated with polycystic ovary syndrome (PCOS), but it can also have other causes. In this article, we will explore what a high AMH result means and answer some common questions about AMH testing.
First off, what is AMH?
AMH is a hormone that is produced by the granulosa cells in the ovarian follicles. It plays a role in the growth and maturation of ovarian follicles in females. AMH levels are relatively stable throughout the menstrual cycle and can be measured in the blood.
AMH is commonly used as a marker of ovarian reserve, which is a rough number of eggs that a female has remaining in her ovaries. Since females are born with a fixed number of eggs, this number naturally declines over time.
What are normal AMH numbers?
What is considered a “normal” AMH level depends on your age, as well as the lab where you take the test. Since there is no international standard, it’s best to use the reference ranges included on the test results (your doctor can share those with you if you did a test through a clinic).
In general, however, an AMH between 1.0 and 3.5 ng/mL suggests a “normal” range that is likely to have a good response to egg freezing.
If you are looking to donate your eggs, however, minimum AMH requirements may be slightly higher. For example, with Cofertility’s Split program, we require a minimum AMH of 2.0, though clinics may have their own unique requirements. This is to increase the chances of retrieving enough eggs to actually split, to ensure positive outcomes for both parties involved.
What AMH level is considered high?
In healthy females of reproductive age, higher levels of AMH mean that the ovaries have a larger supply of eggs. This means one would be expected to have better than average outcomes for egg freezing.
Remember, there is no universal standard for AMH, so it can vary depending on the lab where the test is run. Your test results will include if your range is “normal”, “low”, or “high” and the cut-off can differ. For example, Atlanta Fertility considers over 4.5 ng/mL high. Advanced Fertility considers anything over 4.0 ng/ml high. While RMA would consider an AMH over 3.0 ng/ml as “very high”.
With high levels of AMH, you may be at higher risk for ovarian hyperstimulation syndrome (OHSS). This means your doctor may choose a specific protocol and/or do extra monitoring to decrease the risk of complications during egg freezing.
What AMH level is considered too high?
Again, this question depends on the lab. Your test results will come with a reference range, and will indicate if your number is high for your age. If your doctor considers your levels abnormally high and has concerns, they will discuss the results with you.
Common reasons for high AMH
The most common reason for high AMH is that you are very fertile and likely to retrieve more eggs in an egg freezing cycle.
But a high AMH level may also indicate PCOS, which is a hormonal disorder that affects 8–13% of females of reproductive age. Those with PCOS typically have high levels of androgens (male hormones) and may have irregular periods, acne, and excess hair growth. Patients with an average AMH level ≥ 4.45 ng/ml have a 9.35 times higher likelihood of developing PCOS, but not all patients with a high AMH have PCOS.
In rare cases, abnormally high AMH could be a sign of an ovarian tumor. Certain types of ovarian tumors, such as granulosa cell tumors, can produce high levels of AMH.
Does high AMH always mean PCOS?
While an increase in AMH levels has been reported to be associated with PCOS, high AMH alone is not enough to diagnose PCOS.
Not all patients with PCOS have high AMH levels, and not all patients with high AMH levels have PCOS. Diagnosis of PCOS requires a combination of symptoms, hormone levels, and imaging studies, such as ultrasound.
Does high AMH mean good egg quality?
Not necessarily. While a high AMH level is often associated with a larger number of ovarian follicles and eggs, it does not necessarily mean that the eggs are of good quality. Egg quality is determined by factors such as your age, genetics, and environmental factors, and cannot be measured directly by AMH levels.
Am I ovulating if my AMH is high?
AMH levels do not indicate if you’re ovulating or not. Ovulation is the release of a mature egg from the ovary and can be confirmed by monitoring the menstrual cycle and/or performing ultrasound studies.
Will I get a lot of eggs if I have a high AMH?
The success of egg freezing outcomes largely depends on the number and quality of eggs retrieved. Studies have shown that AMH levels can be used as a predictor of egg quantity, and can thus help to predict the potential success of egg freezing. Those with higher AMH levels tend to have better outcomes with egg freezing, as they are likely to have more eggs retrieved and a higher chance of success in future fertility treatments.
But by no means does a high AMH level guarantee a lot of eggs during an egg retrieval procedure for fertility treatments. The number of eggs retrieved during an egg freezing cycle depends on several factors, including your age, ovarian response to stimulation medications, any other underlying medication conditions, and the skill of the doctor performing the procedure.
What is a good AMH level for egg freezing?
Research has found that AMH is a good predictor of the response to ovarian stimulation and the number of eggs retrieved. Because of this, fertility doctors typically use your AMH levels (along with other biomarkers) to determine the drugs and dosages you will need to maximize your response to ovarian stimulation.
Now, what about a correlation between AMH and actual babies born (live birth rate)? Well, while AMH does seem to have some association with live birth rates after IVF, its ability to actually predict a live birth is not that great. This is especially true for younger people. A 2021 study found that AMH is a good predictor of live birth in older (>39 years old), but not younger, people. They found that younger participants (≤38 years old) could get pregnant even with low AMH levels as long as they had frequent egg retrievals.
Freeze your eggs with Cofertility
One option to make egg freezing better is working with Cofertility. Through our Split program, qualified freezers can freeze their eggs for free when donating half of the eggs retrieved to a family who can’t otherwise conceive.
Through our Keep program — where you keep 100% of eggs retrieved for your own future use — we offer exclusive discounts on expenses, such as frozen egg storage. Keep members also still gain free access to our Freeze by Co Community, a safe space for those engaging in the egg freezing process (or gearing up for it) to connect and lean on each other. It also enables access to exclusive guidance, free expertise, and community events.
By making egg freezing easier and more accessible, our programs further strengthen the American Society of Reproductive Medicine (ASRM)’s Committee Opinion that egg freezing can help promote social justice and strengthen gender equality.
Summing it up
A high AMH level is generally a good sign for your ability to successfully freeze your eggs. But for some, it can also be one indicator of PCOS. While a high AMH level is often associated with a larger number of ovarian follicles and eggs, it does not necessarily mean that the eggs are of good quality (egg quality is more dependent on age).
AMH levels are commonly used as a marker of ovarian reserve and can be helpful, in conjunction with other measures, in predicting the number of eggs that can be retrieved during an egg freezing cycle. However, it is important to keep in mind that egg quality is determined by several factors and cannot be measured directly by AMH levels. If you have concerns about your fertility or AMH levels, it is important to speak with a fertility doctor for personalized advice and treatment options.
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Egg Freezing and Birth Control: An Overview
If you’re exploring egg freezing, you may have a lot of questions, including if you can stay on birth control or not. In this article, we will discuss how birth control works and answer common questions about egg freezing while on various types of birth control.
More and more people are freezing their eggs; in fact, in 2021 we saw a 46% increase in egg freezing cycles in the United States. If you’re exploring egg freezing, you may have a lot of questions, including if you can stay on birth control or not. In this article, we will discuss how birth control works and answer common questions about egg freezing while on various types of birth control.
How birth control works
Birth control methods work in various ways to prevent pregnancy. Hormonal methods, such as the pill, patch, ring, and injection, regulate hormones in the body to prevent ovulation. Without ovulation, there is no egg available for fertilization.
Non-hormonal methods, such as condoms, diaphragms, and intrauterine devices (IUDs), physically prevent sperm from reaching the egg or alter the environment in the uterus to prevent implantation. IUDs can be either hormonal or non-hormonal, depending on the type.
If you are freezing your eggs, do not start or stop your current birth control regimen without talking to your fertility doctor.
Can I freeze my eggs while on the pill?
You will need to stop taking the pill before the actual egg freezing cycle. That’s because hormonal birth control is intended to prevent ovulation, but during freezing you want to do exactly the opposite. Some doctors will have you stop during your egg freezing cycle, and some may have you stop for the month leading up to the retrieval.
The irony is that in preparation for an egg freezing cycle, the birth control pill is commonly prescribed for two to three weeks to sync your cycle and reduce the chance of inducing a cyst from the ovulation follicle. It can also help synchronize the cohort of follicles for a more optimal response. So if you’re not on the pill, you may be prescribed birth control pills with the start of the menstrual cycle in which you plan to undergo the egg freezing cycle.
Can I freeze my eggs while on Depo-Provera?
Depo-Provera (medroxyprogesterone acetate) is an injection that contains a synthetic form of the hormone progesterone. Since this shot can interfere with hormonal medications, you You may have to wait up to three to six months after the last shot until your ovaries are in an optimal state to be stimulated.
While Depo-Provera can affect the timing of ovulation, it does not impact the number or quality of eggs that are retrieved during the egg freezing process.
Can I freeze my eggs with an IUD?
Yes! Unlike other forms of birth control, IUDs do not prevent ovulation and therefore will not get in the way of stimulating egg production during your freezing cycle. If you have an IUD, there’s no need to remove it before your cycle. Although if you’ve been meaning to take it out, ask the doctor if they can do it during your procedure.
Studies show that egg and embryo freezing results are the same for patients with or without IUDs.
Can I freeze my eggs with Nexplanon (birth control implant)?
Nexplanon is a small rod that is inserted under the skin of the upper arm and contains a synthetic form of the hormone progesterone. It can remain in place and does not appear to impact the number or quality of eggs that are retrieved during the egg freezing process.
Can I freeze my eggs with the patch?
Like the pill, the patch contains synthetic hormones that regulate the body's natural hormone levels and prevent ovulation. In order to begin an egg freezing cycle, you will need to remove the patch.
Can I freeze my eggs with NuvaRing?
The NuvaRing is a vaginal hormonal birth control ring. Because it’s using hormones to prevent ovulation, like the pill and the patch, you will need to remove the NuvaRing before your cycle. However, your fertility doctor will give you instructions and there’s no need to remove it until they tell you to.
Why is my doctor prescribing birth control to freeze my eggs?!
While it may seem counterintuitive, many fertility doctors recommend or prescribe birth control at the beginning of the egg freezing process. There are several reasons why:
- To coordinate the timing of stimulation start. Hormonal birth control pills can be used to offset the menstrual cycle to help facilitate the best timing for your cycle with your clinic/lab.
- To reduce the likelihood of ovarian cysts. Birth control pills may help to suppress the growth of ovarian cysts, which can interfere with the egg retrieval process.
So while it may seem counterintuitive, using birth control pills before egg freezing is pretty typical.
Summing it up
Hormonal birth control methods work by regulating hormones in the body to prevent ovulation, while non-hormonal methods physically prevent sperm from reaching the egg or alter the environment in the uterus to prevent implantation. While it is possible to freeze your eggs while on various types of birth control, it depends on which one.
- Definitely okay: condoms, diaphragms
- Generally okay: IUD, birth control implant
- Need to stop: the pill, the patch, NuvaRing
- Potential wait of three-six months: Depo-Provera
Of course, do not start or stop your current birth control regimen without talking to your fertility doctor first.
Freeze your eggs with Cofertility
Cofertility is in the “family” business, striving to make egg freezing and third-party reproduction more human-centered and accessible for all. Our Freeze by Co program allows you to freeze your eggs for free when you give half of the eggs retrieved to a family who can't otherwise conceive.
Can I Freeze My Eggs If…
Common egg freezing questions answered!
Egg freezing, also known as oocyte cryopreservation, is a process in which a woman's eggs are retrieved, frozen, and stored for future use. It has become an increasingly popular option for those who want to preserve their fertility for later in life, whether due to medical reasons or personal choice. We get a lot of questions from people wondering if egg freezing is an option for them, given their unique circumstances. In this article, we will share the most common questions we get and hopefully settle some debates once and for all.
Can I freeze my eggs if I have PCOS?
Absolutely. Like others, women with PCOS may want to freeze their eggs to proactively increase their chances of having children down the road. It’s best to freeze when you are younger, in order to get a greater number of eggs and the highest quality eggs possible.
You’ll want to make sure you work with the best doctors, because women with PCOS are more susceptible to developing ovarian hyperstimulation syndrome (OHSS) during egg freezing. This is because they are likely to have more follicles, and the more follicles an ovary has the more likely it is to be overstimulated by HCG, one of the drugs used during egg freezing.
Can I freeze my eggs if I have endometriosis?
Yes. Some doctors will actually recommend egg freezing for women with endometriosis while they're young and the condition is still in the early stages. Because some surgeries for endometriosis can worsen fertility by inadvertently removing healthy ovarian tissue or compromising vascular supply to the ovary, egg freezing should be done before any such surgeries.
Can I freeze my eggs if I’m a virgin?
Being a virgin does not prevent you from being able to freeze your eggs for future use. The egg freezing process is the same for all patients, and it does not involve any kind of sexual contact. If you are considering egg freezing, reach out to see if we can help.
Can I freeze my eggs if I’m on birth control?
It depends on which type! Hormonal birth control methods work by regulating hormones in the body to prevent ovulation, while non-hormonal methods physically prevent sperm from reaching the egg or alter the environment in the uterus to prevent implantation. While it is possible to freeze your eggs while on various types of birth control, it depends on which one.
- Definitely okay: condoms, diaphragms
- Generally okay: IUD, birth control implant
- Need to stop: the pill, the patch, NuvaRing
- Potential wait of three-six months: Depo-Provera
Of course, do not start or stop your current birth control regimen without talking to your fertility doctor first.
Can I freeze my eggs if I have HPV?
An HPV diagnosis alone should not affect your ability to get pregnant or to freeze your eggs. Most fertility specialists will require an up to date pap smear and HPV test as part of their evaluation and you’ll usually be allowed to continue with the freezing process as long as the HPV is low-risk, since those cases are expected to clear on their own.
If you do have a high-risk HPV, you’ll need to discuss those results with both your OB/GYN and your fertility doctor to figure out what next step is right for you. Depending on the specific HPV strain, if there are any lesions and how advanced they are, your doctor will recommend continuing with egg freezing or delaying until after treatment.
Can I freeze my eggs if I’ve had gender affirming surgery?
It depends on what was involved in the surgery. If the ovaries were removed (an oophorectomy or total hysterectomy), you will not be able to freeze your eggs. This is because egg freezing requires the ovaries to produce mature eggs, which are then retrieved and frozen for future use. If the ovaries have been removed, then the eggs were removed too and egg freezing is not an option.
Can I freeze my eggs if I have started hormone therapy?
If you have already started hormone therapy, such as testosterone (T) therapy, it may still be possible to freeze your eggs. However, your doctor will likely recommend discontinuing testosterone until your period returns (usually under six months) to begin the egg freezing process.
Can I freeze my eggs if I’m afraid of needles?
Yes, it does involve both injections and blood draws. This is because the process of egg freezing involves stimulating the ovaries with hormones (aka fertility medication) to produce multiple eggs, which are then retrieved with a needle. There are also blood draws to determine your hormone levels, and an IV for sedation during the retrieval itself. If you are afraid of needles, it's important to acknowledge your fear and work through it. Ignoring or avoiding the issue will only make it worse.
Can I freeze my eggs if I vape?
While the effects of vaping on fertility are still largely unknown, many fertility clinics advise their patients to quit vaping in an effort to improve egg freezing outcomes related to quality and quantity based on the above research on smoking. Lower quality eggs with a higher DNA damage rate could impact the success of a future pregnancy using these frozen eggs, as these eggs may be less likely to fertilize into embryos (or result in a successful implantation). In addition, fewer eggs retrieved from those who vaped may result in fewer options for future use, which can increase the likelihood of needing additional egg freezing cycles.
Can I freeze my eggs if I drink?
Yes, but alcohol consumption is not recommended during the egg freezing process itself. Studies have shown that alcohol consumption can negatively impact fertility and may also increase the risk of certain complications associated with egg freezing. The good news is there are loads of EANABs (equally-appealing, non-alcoholic beverages) these days. Try a soda water with lime and no one will bother you!
Can I freeze my eggs if I’m a smoker?
Smoking is not recommended during the egg freezing process (or ever!). Studies have shown that smoking can negatively impact fertility and may also increase the risk of certain complications associated with egg freezing. Smoking can decrease the number and quality of eggs retrieved, and increases the risk of ovarian hyperstimulation syndrome (OHSS), a potentially serious complication of the egg freezing process.
Can I freeze my eggs if I'm over a certain age?
American Society for Reproductive Medicine (ASRM) does not recommend egg freezing for people older than 38, but this isn’t a strict cutoff. Everyone’s ovarian reserves declines at a different rate. Having your fertility hormones checked can sometimes help you and your doctor get a general idea of what your ovarian reserve is. This can better help you decide if egg freezing is right for you.
Can I freeze my eggs if I'm not ready to have children yet?
Absolutely! Egg freezing is often chosen by those who are not yet ready to start a family, but want to keep options open for the future. It’s important to understand that the younger you are when you freeze your eggs, the higher the chances of success.
Can I freeze my eggs if I have already had children?
Absolutely. In fact, some people choose to freeze their eggs after having children, including those who went through divorce, as a way to preserve their fertility for future pregnancies.
Can I freeze my eggs if I have had my tubes tied?
If you have had a tubal ligation (commonly known as "getting your tubes tied"), you can still be a candidate for egg freezing as the process does not require the fallopian tubes to be open.
Can I freeze my eggs if I’m on antidepressants?
For sure. The most commonly used antidepressant (SSRIs) and anti-anxiety medications (benzodiazepines) don’t have any clear, long-term impacts on egg quantity or quality, ovulation, or chances of conception (though SSRIs do have short-term effects on sperm).
Can I freeze my eggs if I have diabetes?
While egg freezing can be a game-changer, it's not without risks. Women with diabetes may have an increased risk of ovarian hyperstimulation syndrome (OHSS). However, with proper medical supervision and careful management of blood sugar levels, most women with diabetes successfully undergo egg freezing.
Let us help you freeze those eggs!
Cofertility is a human-first, tech-enabled fertility ecosystem that provides people agency over if, how, and when they have babies — today or someday. We have two programs for egg freezers:
- Our Split program, which offers women a chance to both freeze their own eggs and donate half the eggs to a family who cannot conceive otherwise. If you qualify for the program and decide to donate half of your retrieved eggs, every expense associated with the egg freezing procedure — medications, supplements, travel if necessary, insurance, and 10 years of storage — is completely free of charge. We don’t even need a payment or credit card up front, as the family you match with covers all the expenses.
- Our self-pay Keep program allows women to freeze their eggs and keep them all for their future use. Through Keep, we offer our members partnerships and discounts to lighten the financial load of egg freezing, as well as access to our member community.
The benefits for of working with Cofertility include:
- Power of choice: Freeze your eggs more affordably or, if you qualify, freeze for free when you give half to a family who can’t otherwise conceive.
- Community: Our inclusive online spaces allow you to connect with others going through the process in our private online community.
- Compassion: We’ll always treat you with care, and our Split program gives you the opportunity to make someone’s family building dreams a reality.
- Data-driven: We provide you with trustworthy guidance and evidence-based research so you can make informed decisions about your fertility.
- Free egg freezing: Freeze and store your eggs for 10 years, entirely for free if you qualify for our Split program.
Ready to learn about more affordable (even free!) egg freezing with Cofertility? Fill out this quick quiz to learn about our accessible egg freezing options and see if you qualify for our programs — it only takes one minute.
Egg Freezing: Chances of Live Birth by Age and Number of Eggs Retrieved
In this guide, we’ll try and answer one of the most common questions around egg freezing: the chances of live birth.
Embarking on the path of family planning is an exciting journey filled with hope and, often, uncertainty. One area that typically gives rise to a multitude of questions revolves around oocyte cryopreservation, commonly known as egg freezing. While this medical breakthrough has provided countless women with greater reproductive autonomy, it's still not a definitive guarantee of biological motherhood.
In this guide, we’ll try and answer one of the most common questions around egg freezing: the chances of live birth.
From frozen eggs to baby
At every stage of the in vitro fertilization (IVF) process (which is technically what egg freezing is, plus embryo fertilization in a lab), there's a certain level of attrition. Some collected eggs may be immature, making them unsuitable for freezing. Others may not withstand the thawing process. When you’re ready to fertilize those eggs into embryos, they will not necessarily all fertilize, and some fertilized embryos may fail to mature into viable embryos suitable for transfer. Even embryos that reach the transfer stage might not be genetically normal. And those that are genetically normal may not result in a viable pregnancy or live birth.
As a result, egg freezing is better viewed as a way to increase your chances of pregnancy down the line, rather than an insurance policy or a surefire plan. It’s a path filled with potential, and definitely gives you greater optionality when you’re ready to have kids, but — and we are always very transparent about this — there is unfortunately no absolute promise of a live birth at the end of the egg freezing process.
How many eggs should I freeze?
Given these complexities, a pressing question for many women is, “how many eggs should I freeze to increase my chances of having a baby?” The answer is nuanced and largely depends on two variables: the age at which the eggs are frozen, and how many children you want.
Unfortunately, the quality of eggs can't be assessed before fertilization is attempted, adding another layer of uncertainty to this equation. Still, we can provide an approximate guide based on averages, which can inform individualized counseling, treatment planning, and expectation management.
One study out of Harvard Medical School of 520 cycles found the chances of live birth varies based on age and number of eggs frozen (see chart below). This guidance is not precise, but offers an approximate benchmark to guide you through your fertility journey.
How many eggs will I get?
Another common inquiry from patients is how many eggs are likely to be retrieved and preserved in a single egg freezing cycle. The good news is that this is fairly easy for fertility doctors to predict using two crucial measures: anti-Müllerian hormone (AMH) and antral follicle count (AFC).
AMH and AFC, both estimators of ovarian reserve, can provide an approximation of the number of eggs that can be retrieved from a stimulated cycle. For instance, an AMH level of 15 pmol/L (2.1 ng/mL) could predict a yield of approximately 12 to 18 eggs. Similarly, AFC's numerical value directly correlates with the number of eggs potentially collected in one cycle, with a rough ratio of 1:1. So if your fertility doctor counts 15 antral follicles during the transvaginal ultrasound, you could potentially retrieve 15 eggs in a single cycle (note this number could be lower or higher based on other factors).
Will I have enough eggs to share?
Cofertility’s Split program offers women a chance to freeze their eggs *for free* when donating half of the eggs retrieved to a family who cannot otherwise conceive. If you qualify for the program and decide to donate half of your retrieved eggs, every expense associated with the egg freezing procedure — medications, supplements, travel if necessary, insurance, and 10 years of storage — are completely free of charge.
Since the number of eggs is predictable with AMH and AFC, we’re only able to accept people into the program if we are confident they would have enough eggs to “split”.
Setting expectations
You can look at the probabilities and hormonal indicators, but everyone’s egg freezing journey is unique. Age, health, lifestyle, and genetic factors can all play a role in your path to motherhood. Remember, egg freezing is a science, but it's not an exact one. The uncertainties are part of the process. And while the prospect of attrition can seem daunting, it's important to remember that every step forward is a step closer to the potential for success.
Navigating these complexities can feel overwhelming, which is why support and guidance are crucial. At Cofertility, our mission is to guide you through this journey, providing you with the necessary information, support, and encouragement to make the best decisions for your fertility future.
Although egg freezing can't offer guaranteed outcomes, it has undoubtedly provided hundreds of thousands of women worldwide with expanded options and increased flexibility in their reproductive timelines. By understanding the process's intricacies and setting realistic expectations, we can navigate this journey together, with optimism, resilience, and hope.
Freeze your eggs with Cofertility
Cofertility is a human-first, tech-enabled fertility ecosystem that provides people agency over if, how, and when they have babies — today or someday. We have two programs for egg freezers:
Our Split program offers women a chance to freeze their eggs for free when donating half of the eggs retrieved to a family who cannot otherwise conceive. If you qualify for the program and decide to donate half of your retrieved eggs, every expense associated with the egg freezing procedure — medications, supplements, travel if necessary, insurance, and 10 years of storage — are completely free of charge. We don’t even need a payment or credit card up front, as the family you match with covers all the expenses.
Our self-pay Keep program allows women to freeze their eggs and keep them all for their future use. Through Keep, we offer our members partnerships and discounts to lighten the financial load of egg freezing, as well as access to our member community.
The benefits for of working with Cofertility include:
- Power of choice: Freeze your eggs more affordably or, if you qualify, freeze for free when you give half to a family who can’t otherwise conceive.
- Community: Our inclusive online spaces allow you to connect with others going through the process in our private online community.
- Compassion: We’ll always treat you with care, and our Split program gives you the opportunity to make someone’s family building dreams a reality.
- Data-driven: We provide you with trustworthy guidance and evidence-based research so you can make informed decisions about your fertility.
- Free egg freezing: Freeze and store your eggs for 10 years, entirely for free if you qualify for our Split program.
Ready to learn about more affordable (even free!) egg freezing with Cofertility? Fill out this quick quiz to learn about our accessible egg freezing options and see if you qualify for our programs — it only takes one minute.
Read more:
When to Test Your Fertility
When to test your fertility, the importance of early fertility awareness, and proactive measures you can take to understand it.
I was 28 when I first started trying to conceive. I vividly remember taking my last birth control pill, throwing out my pack, and texting my friend to tell her we were no longer “not trying,” excited but nervous. Sounds pretty standard, right? Unfortunately, what I didn’t know at the time was that I was about to embark on a two-and-a-half-year journey to get pregnant with my son. This included several pregnancy losses, a few rounds of IVF, and lots of questions, including, “should I have tested my fertility sooner?”.
I don’t share this to scare anyone. But my story is not all that uncommon. In fact, 1 in 6 individuals experience some form of fertility challenge.
I was woefully unprepared. And because of this lack of preparedness by Sex Ed as well as limited time with my OBGYN, it probably took a good six months before I started to understand what actually goes into conceiving a healthy pregnancy: timing, lifestyle, genetics, and more. So much of my time, stress, and probably money could have been saved by proactive fertility testing.
In this article, we’ll discuss when to test your fertility, the importance of early fertility awareness, and proactive measures you can take to understand it. If you take one thing away from this article, though — the best time to test your fertility is right now. Let’s talk about why.
So what is fertility testing, anyway?
Before we dive into when to test your fertility, it’s important to understand what fertility testing even is.
Ovarian reserve testing
A fundamental concept of assessing one’s fertility is to understand their ovarian reserve. This involves evaluating the quantity of a woman's remaining egg supply (oocytes) in her ovaries. One of the most widely used tests for ovarian reserve (though not without its limitations — more on that below) is the measurement of Anti-Mullerian Hormone (AMH) levels, which can be done with a simple blood test.
Understanding AMH
AMH is a protein produced by cells in the ovarian follicles, with levels of AMH in your blood providing an indication of the number of eggs remaining in your ovaries. If you’re considering egg freezing, AMH testing is especially valuable, as it helps assess your starting point and may indicate a timeline of how urgently you may want to move forward with freezing your eggs.
Your AMH may also give a sense of how your ovaries might respond to the actual egg freezing process. Lower AMH levels typically suggest a diminished ovarian reserve, which may impact fertility potential. In general, an AMH between 1.0 - 3.5 ng/mL is considered a “normal” range.
Individuals with a higher AMH level — which varies by lab, but could be anywhere over 3.0 ng/ml — usually have a better response to ovarian stimulation, leading to a higher number of eggs likely to be retrieved during the procedure. That said, a higher AMH also carries a greater risk of ovarian hyperstimulation syndrome (OHSS), so your doctor will need to be careful with your medication protocol and monitoring.
Should I test my fertility at home or in a clinic?
At-home fertility tests have gained popularity in recent years due to their convenience and privacy. These tests typically involve collecting blood or urine samples and mailing them to a laboratory for analysis. On the other hand, in-clinic fertility tests are conducted at a medical facility, where specialized equipment and healthcare professionals are available.
The pros of at-home fertility tests
- Convenience and privacy: Samples can be collected in the comfort of your home.
- Cost-effective: At-home tests are often more affordable than in-clinic procedures.
- Early assessment: At-home tests allow you to gain insights into your fertility potential before actively trying to conceive. Plus, you won’t have to wait to get squeezed in for an appointment at the clinic!
The pros of testing your fertility at a clinic
- A broader scope: At-home tests may not provide a comprehensive evaluation of fertility health, while testing your fertility at a clinic provides a more comprehensive picture of your fertility. An important note is, when testing your fertility at a clinic, you’ll also undergo a transvaginal ultrasound, where the technician or doctor will be able to get a view of what’s going on in those ovaries and the number of follicles available this cycle.
- Better accuracy: Some at-home tests may have varying levels of accuracy when compared to in-clinic tests.
- Face time: At a clinic, you’ll have the ability to chat directly with a doctor, before and after your results.
When should I test my fertility?
So, when is the “right” age for testing your fertility, anyway?
It depends.
And ultimately, it’s up to you! It’s your body, and your data, and there is no one-size-fits-all answer. We’re firm believers that knowledge is power and you deserve this information. Studies do show that our ovarian reserve declines with age — in other words, it’s a good idea to assess your fertility potential sooner rather than later. That way, if you do want to preventatively freeze your eggs, you can do so while your ovarian reserve is still higher.
According to the American Society for Reproductive Medicine (ASRM), the optimal time to freeze your eggs is in your 20s and early 30s. And this study indicated that, as we get older, our chances increase of needing to do multiple egg freezing cycles in order to achieve a 70% live birth rate. We know we’re a bit of a broken record here, but: the younger you are, the healthier and more plentiful your eggs are.
Consider your egg freezing plans
Because the ASRM doesn’t recommend egg freezing for people older than 38 (although this is not a hard and fast rule), it’s a good idea to test your fertility earlier on if possible. That way, should you decide to move forward with egg freezing, you’ll have the time and space to come up with a plan and hopefully see some successful results.
If and when you decide to move forward with egg freezing, you can freeze your eggs more affordably (even for free!) with Cofertility. Fill out this quick quiz to learn about our accessible egg freezing options and see if you qualify for our programs — it only takes one minute.
Should I test my fertility in my 20s?
Testing your fertility in your 20s gives you the most flexibility. Whether your testing looks great and you want to freeze your eggs now, or you uncover potential fertility risks to address, the more time you have, the better.
Your doctor may even recommend fertility testing if you have past or current reproductive health issues, including sexually transmitted infections (STIs), endometriosis, or PCOS, all of which can contribute to fertility challenges. Even if you’re not yet sure if you want to start a family in the future, testing your fertility in your 20s may help you make informed decisions about family planning options down the line.
Best at-home fertility tests
If you’re curious to learn more about your ovarian reserve, talk to your doctor about fertility testing. If your doctor won’t order the tests…you might want to find a new one who listens to your concerns and takes them seriously. But in the meantime, there are many great at-home fertility testing options out there.
LetsGetChecked Ovarian Reserve Test
Cost: $139
Hormones measured: AMH
Why we like it: While it only tests one hormone, the test is simple and fast. It’s also the least expensive of the three, plus you can get 25% off with code COFERTILITY25.
Natalist Women’s Fertility Test
Cost: $149
Hormones measured: estradiol, LH, FSH, TSH, and total testosterone
Why we like it: Natalist provides comprehensive insights into ovarian reserve, empowering individuals to assess their fertility potential in the comfort of their own homes. Plus, it’s a woman-owned and woman-run company. Use Cofertility20 for 20% off your entire purchase.
Remember: at-home fertility tests aren’t without limitations
Although at-home fertility tests are a great way to get a peek behind the curtain of your fertility, they aren’t without limitations. For starters, according to recent studies, measuring AMH alone may not predict your time to pregnancy. As mentioned above, testing your fertility with a doctor at a clinic will likely provide a more comprehensive picture of your fertility outlook, especially as they consider your medical history, and conduct a physical exam and transvaginal ultrasound. Of course, you’ll also get professional interpretation of the results that you may not receive with an at-home fertility test.
All of that being said, any fertility testing (whether at home or in a clinic) only measures your fertility at that given point in time. It should not be taken as a guarantee for future outcomes. It also can’t tell you anything about your egg quality, which cannot be truly observed until it comes time to actually fertilize those eggs.
Consider egg freezing as a proactive measure
After testing your ovarian reserve, it’s worth considering freezing your eggs if you don’t want kids soon. We’ll be the first to say that egg freezing is not a guarantee for a successful pregnancy in the future — those eggs need to be fertilized into embryos, transferred to a uterus, and then carried for 40 weeks to result in a live birth! But because our fertility declines with age, the earlier we preserve it, the more set up for success we may be in the future if we do need to use those eggs down the line.
How does egg freezing work?
As a primer, egg freezing allows individuals to preserve their fertility by freezing and storing their eggs for future use (fertilization). Let’s get into some of the specifics.
Some benefits of egg freezing
There are many reasons why egg freezing can be beneficial, including:
Delaying parenthood: Egg freezing enables individuals to postpone childbearing to pursue educational, career, or personal goals while increasing their chances of having a healthy pregnancy down the line.
Medical reasons: Some medical treatments, such as chemotherapy or radiation, can impact fertility. Egg freezing offers a proactive option for individuals facing medical conditions that may affect their reproductive health.
Preserve higher quality eggs: As we age, our ovarian reserve diminishes, and the quality of our eggs declines. By freezing eggs at a younger age, individuals can preserve their eggs when they are of higher quality.
The egg freezing process
Overall, the egg freezing process is a 10-14 day period involving ovarian stimulation, the actual egg retrieval, and storing the frozen eggs. Here’s what goes into each.
Ovarian stimulation: Before the egg retrieval, individuals typically take injectable hormone medications for about 10-14 days. This process encourages the ovaries to produce multiple mature eggs. You’ll head to the clinic for monitoring every few days (more frequently as you get closer to your retrieval) so your doctor can check on how things are progressing and make updates to your medication protocol if needed.
The egg retrieval: Once the eggs are mature, a minimally invasive procedure known as transvaginal ultrasound-guided aspiration is performed to retrieve the eggs from the ovaries. The procedure is usually well-tolerated and does not require a surgical incision.
Cryopreservation: After retrieval, the eggs are frozen using a process called vitrification. This method prevents the formation of ice crystals, which could damage the eggs during freezing. You’ll store your eggs in a special storage facility meant for just that.
For an in-depth overview of the egg freezing process, click here.
Success rates of egg freezing
The success of egg freezing largely depends on the age at which the eggs are frozen. Generally, eggs frozen at a younger age have a higher chance of resulting in a successful pregnancy. Advanced vitrification techniques have significantly improved egg freezing success rates, with some studies reporting comparable pregnancy rates between fresh and frozen-thawed eggs.
One study of 1,241 women found that the average number of eggs retrieved on the first egg freezing round was:
- 21 eggs for women under 35
- 17 eggs for women 35-37
- 14 eggs for women 38-40
But, in addition to egg quantity, we also need to consider egg thaw survival rate, and the rate at which these eggs become embryos and result in a live birth. According to a study in the Journal of Assisted Reproduction and Genetics, a woman under 35 will need 9 eggs to achieve a 70% chance of having at least one live birth. If you’re trying to conceive in your mid to late 30s, you may need double as many eggs to achieve that same 70% success rate.
Not only will freezing your eggs proactively give you the options of utilizing higher quality eggs in the future, it also helps alleviate the pressure of finding a reproductive partner, and can allow us to feel empowered to make family planning decisions on our own terms without any compromises. Taking a proactive approach to fertility preservation can provide the freedom to pursue opportunities without sacrificing the dream of having a family when the time is right.
Freezing your eggs with Cofertility
With Freeze by Co, you have the opportunity to apply to our Split program, where you can freeze your eggs for free when you donate half of the retrieved eggs to a family that can’t otherwise conceive. The cost of the entire process, including 10 years of cryopreservation, is fully covered.
Or, if you want to freeze and store your eggs for your own future use without donating, as part of our Keep program, we offer lower prices on things like consultations and storage, along with access to our community of others going through the process at the same time. Plus, you’ll have direct access to our team, which is here to support you throughout the entire journey.
Summing it up
If you’re considering testing your fertility, the best age to do it is now. Whether you test yourself at home, or with a doctor at a fertility clinic, testing your fertility can provide valuable insights into what your family-building future may look like. It might also uncover the need for egg freezing in order to preserve some of your existing fertility as it stands today. But whatever you decide to do with the results, you’ll at least be armed with more information about yourself than you would have had otherwise.
How to Increase Egg Freezing Chances of Success
If you’re thinking about freezing your eggs, you probably have tons of questions. In this article, we’re going to focus on a very common question: “How can I increase my chances of success when I freeze my eggs?”
More and more people in the US (and the rest of the world) are taking control of their reproductive health and fertility by choosing to freeze their eggs. Whether this is so they can focus on a career, get an insurance policy with coverage for treatments, or because of medical reasons, this has allowed people to delay having children until whenever they’re ready to start a family.
If you’re thinking about freezing your eggs, you probably have tons of questions. In this article, we’re going to focus on a very common question: “How can I increase my chances of success when I freeze my eggs?”
Factors that can affect egg freezing success rates
Before an egg freezing cycle
Let’s start by going through what specific things make a difference in your chances of success before you even freeze your eggs.
Age
Age has been proven by countless research studies to be one of the biggest determinants of egg quality. As a person ages, their eggs are more likely to become aneuploid, meaning they’re genetically “abnormal.” This can lead to issues with both getting and staying pregnant (i.e, higher risk of miscarriages). On top of that, as a person ages, the number of eggs their ovaries contain continues to decrease naturally. Once a person reaches their mid to late thirties, the quality and quantity of eggs starts to go down more quickly. While there is no “perfect” age at which to freeze your eggs, freezing them before you reach your late 30s is considered ideal.
AMH level
Another important factor is your Anti-Müllerian hormone (AMH) level. This is a simple blood test that is commonly used to tell us a person’s reproductive potential based on the number and the quality of eggs they have left in their ovaries. AMH is released by antral follicles, which are small, fluid-filled sacs in the ovaries that each contain a single oocyte (immature egg). Your AMH level is positively correlated with the number of antral follicles you have in your ovaries. Simply stated, the more follicles you have, the higher your AMH level typically is. AMH naturally goes down as a person gets older until it reaches close to zero during perimenopause. While there is no international standard for what a normal AMH level is, some studies have tried to create models for what’s considered normal for specific ages. Check out this article to find out more about AMH levels at different ages.
Antral follicle count
Antral follicle count (AFC) is another number to be aware of before egg freezing. AFC is used in fertility assessments to estimate the number of developing follicles in someone’s ovaries at a specific point in the menstrual cycle using ultrasound. As mentioned before, the more follicles you have (the higher your AFC is), the higher your AMH level. And just like your AMH, your AFC will also naturally go down as you age.
How these values affect your egg freezing success
Unfortunately, there isn’t a lot that can be done about aging or about the decline in AMH and AFC that goes with it but there are a few things to know about how they affect your egg freezing changes.
- Ovarian reserve assessment. Age, AMH and AFC all provide valuable information about a person’s ovarian reserve. In general, younger age, higher AMH levels, and a higher AFC are good indicators that you have a larger pool of potential eggs in the ovaries. This means that you’re more likely to produce more eggs during an egg retrieval cycle, which increases the chances of a successful egg freezing cycle.
- Response to ovarian stimulation. Part of the egg freezing cycle includes taking medications to stimulate the ovaries to develop multiple eggs at once (as opposed to just one during a natural, unmedicated menstrual cycle). The response to these medications can vary based on age, AMH, and AFC. People who are younger and those who have a higher AFC/AMH tend to have a better response and produce more mature eggs during the stimulation. This increases the chances of retrieving a larger number of high-quality eggs for freezing.
- Number of cycles. In some cases, people with a lower AFC and/or AMH may have to go through more than one egg freezing cycle in order to get an adequate number of eggs. This can get costly and time-consuming pretty quickly.
- Future fertility potential. The number and quality of frozen eggs affects the chances of having a successful pregnancy when the frozen eggs are later thawed, fertilized, and transferred during an in vitro fertilization (IVF) treatment. A higher AFC and AMH can mean a higher number of frozen eggs, which increases a person’s chances of success in the future. However, neither of these numbers is the end-all-be-all here. In fact, while AMH does seem to have some association with live birth rates after IVF, its ability to actually predict a live birth is not that great, especially for younger people.
Again, all three of these factors aren’t necessarily things you can change so it can be easy to get discouraged if your values aren’t where you want them to be. Remember that each of these is just one value your provider looks at to assess your overall reproductive potential. No value by itself can completely predict your chances of conceiving naturally or define your fertility. A comprehensive assessment of a person’s fertility potential has to be done by a fertility specialist before jumping to any conclusions and making decisions about fertility preservation.
During an egg freezing cycle
Now, let’s go through the factors during an egg freezing cycle that can affect your chances of success.
Quantity and quality of eggs retrieved
The success rates of egg freezing cycles are significantly influenced by both the number and quality of eggs retrieved. The number of eggs retrieved is important because it directly correlates with the chances of developing viable embryos after thawing. This is definitely a case of “more is more”--the more eggs that are successfully frozen, the higher the probability of having viable embryos when the time comes.
However, the quality of the retrieved eggs is just as important. High-quality eggs have a better chance of surviving the freezing and thawing process than low-quality ones. So, as you can imagine, a cycle with lots of eggs that are all low-quality isn’t necessarily more successful than another cycle that produced less eggs but they’re all high-quality.
As a result, fertility providers will always aim to maximize both the quantity and quality of the eggs retrieved. This is essential for improving the success rates of egg freezing cycles so that, ultimately, we end up with healthier embryos and better chances of a successful pregnancy.
Type of freezing method used
There are two main techniques used for freezing eggs: slow freezing and vitrification. The slow freezing method involves gradually lowering the temperature of the eggs, which allows ice crystals to form within the cells. This process can damage the delicate internal structure of the eggs, which can lead to lower viability and success rates once the eggs are thawed. In contrast, vitrification is a freezing process that solidifies the eggs quickly without forming ice crystals. This method protects the cell’s internal structures better and has been shown to increase post-thaw survival rates. This in turn, means higher success rates during IVF treatments. It makes complete sense, then, that vitrification has become the preferred way to freeze eggs.
Tips to increase egg freezing success rates
Alright, so now that we’ve established what’s important when it comes to egg freezing, what exactly can you do to maximize these factors for yourself?
- Consider freezing your eggs at a younger age. There may not be much we can do about the fact that we’re all getting older but in terms of egg freezing, the general rule is that the younger you can do it, the better. According to the American Society for Reproductive Medicine (ASRM), the ideal time to freeze your eggs is in your 20s and early 30s, while you have more eggs and those eggs are healthier. So, whether you’re 25 or 35, your eggs today are still probably healthier than your eggs in one, five or 10 years!
- Optimize your fertility health before beginning the egg freezing process. This step will look a little different from person to person since everyone has their own unique medical history and concerns. Generally speaking though, optimizing your health will include following a balanced diet and making other healthy lifestyle choices. In some cases, you may want to consider adding certain vitamins and supplements to your regimen too. Make sure to talk to your fertility specialist if you’re not sure!
- Consider using a different type of freezing method. Ask your fertility provider which method they plan to use when freezing your eggs. Vitrification is the more common method now given its improved outcomes when compared to slow freezing but it doesn’t hurt to confirm that this is the method your particular clinic uses.
- Consider doing multiple egg retrieval cycles. If you have the resources and time to do multiple cycles, this can vastly improve the pool of eggs to choose from in the future. This is an especially helpful option for people who are older or have a low AMH level or AFC. If your fertility provider thinks more cycles will improve your chances, they’ll discuss those recommendations with you.
- Be particular about the clinic you choose. There are a ton of fertility clinics to choose from nowadays, so take the time to do some detective work and find one that works for your needs. If you know people who’ve used a fertility clinic, ask them for their honest opinions. Read reviews. Look up the providers’ credentials (usually listed on the clinic’s website). You can also find out the clinic’s success rates in terms of live births and other important statistics through their website. Schedule a couple consultations to compare your options. Make sure to come with questions and to actually ask them all. If you’re not sure what to ask, check out some suggestions here.
Emotional considerations
It’s important that we take a second to talk about the emotional side of this experience. For many people, the decision to freeze their eggs is tied to hopes of preserving future fertility. When a lab test or a cycle doesn't yield the desired results, there can be feelings of hopelessness, frustration, sadness, anxiety, and uncertainty about future family planning options. On top of that, this isn’t a cheap or simple process! So there can be disappointment stemming from both the financial and physical investments that have been made.
Because of all of this, seeking support and guidance throughout this process has to be a priority. Support from both loved ones and through professional counseling can make a huge difference when it comes to coping with the emotions you might be dealing with.
Establishing clear and open communication with your fertility providers also plays a key part in helping people cope with the challenges that might come up. Your providers know the ins and outs of your particular situation so they’re the most qualified to tell you what you need to prioritize (and what you can ignore) to improve the success of your egg freezing cycle(s).
With all the nuances involved here, it’s important not to get lost in the weeds. Fertility is impacted by so many factors that you can drive yourself crazy trying to manage all of them. Remember, you are more than any number.
Conclusion
To recap, there are several different factors that can affect the success of an egg freezing cycle including your age, AMH level, AFC, the number and quality of eggs retrieved, and the type of freeing method used. Some of these, you don’t have control over. For the ones you can control, there are a few things you can do.
Optimizing your fertility health before the egg freezing process, freezing your eggs at a younger age, doing more than one cycle, and using a safer freezing option are all ways that you can improve your chances of a successful freezing cycle. This process can be so overwhelming— focusing on the things that you can control can help you feel more grounded throughout your fertility journey.
Freeze by Co is here to help you every step of the way on that journey. With our Keep program, you’re able to freeze your eggs and keep them all for yourself, on your timeline. In addition, you’ll have access to our online support community, the Nest. This is a valuable resource that lets you engage with other people freezing their eggs at the same time!
Your Definitive Guide to Egg Freezing: Risks, Costs, Success Rates, and More
I’m Dr. Meera Shah, a double-board certified OBGYN and Reproductive Endocrinologist (REI). I have helped countless women freeze their eggs as a fertility doctor and as a Medical Advisor to Cofertility. This article is a guide to everything you need to know to make a confident, informed decision about egg freezing.
Egg freezing, also known as oocyte cryopreservation, is a process where a woman's eggs are retrieved, frozen, and stored for later use. This allows women to preserve their eggs at their current age, potentially increasing their chances of having a biological child in the future.
Egg freezing is becoming more and more common, with a 30% increase in egg-freezing cycles from 2021 to 2022 alone!
I’m Dr. Meera Shah, a double-board certified OBGYN and Reproductive Endocrinologist (REI). I have helped countless women freeze their eggs as a fertility doctor and as a Medical Advisor to Cofertility. This article is a guide to everything you need to know to make a confident, informed decision about egg freezing.
Why people choose to freeze their eggs
There are many reasons why women opt for egg freezing. Here are some of the most common reasons we hear:
- Focusing on other priorities: Women focusing on career or personal goals can freeze their eggs until they're ready to start a family.
- Waiting for the right partner: As the average age of first marriage continues to rise, some women choose to freeze their eggs instead of rushing into a marriage.
- Medical reasons: Women facing medical conditions or treatments that could impact fertility, such as chemotherapy or radiation, can freeze their eggs before undergoing these treatments.
- Genetic predisposition: Women with a family history of early menopause may choose to freeze their eggs to ensure they have viable eggs for future use.
- Peace of mind: Some women simply want the peace of mind knowing they have a backup plan for their fertility.
At what age should you freeze your eggs?
There is no perfect age at which to freeze your eggs. However, the younger you can do it, the better. According to the American Society for Reproductive Medicine (ASRM), an optimal time to freeze your eggs is in your 20s and early 30s, while you have a higher ovarian reserve and eggs are healthier.
A large 2020 study at a fertility clinic that specializes in this area looked at egg freezing cycles for over 1,200 people. It compared the average number of eggs people of different ages were able to freeze versus the “optimal” or goal number of eggs they should freeze. This goal number was based on how many eggs would give them a 70% live birth rate after doing 1 or 2 egg freezing cycles (this rate is calculated using some other numbers and it typically goes up as we age to make up for the lower number of healthy eggs).
The study found that younger people, unsurprisingly, have an easier time freezing the goal number of eggs in one cycle. As people aged, they needed multiple egg freezing cycles to reach that goal number.
Read more in What’s the Best Age to Freeze My Eggs?
Is it worth freezing eggs after age 35?
The findings from the study above bring up a common question–is it worth freezing eggs after age 35? Well, it depends. The ASRM does not recommend egg freezing for people older than 38, but this isn’t a strict cutoff.
Your biological clock is not a cliff. Everyone’s fertility decreases down at a different rate. Having your fertility hormones checked can sometimes help you and your doctor get a general idea of your ovarian reserve and chance of a future pregnancy. This can better help you decide if egg freezing is right for you.
Egg freezing success rates by age
Success rates with egg freezing depend on a lot of factors: your health, your ovarian reserve, your response to egg freezing medication, and the quality of the clinic. That being said, generally, younger women have higher success rates due to better egg quantity and quality.
A study of 1,241 women found that the average number of eggs retrieved on the first egg freezing round was:
- 21 eggs for women under 35
- 17 eggs for women 35-37
- 14 eggs for women 38-40
Because women in their 30s tend to produce less eggs, at this age you may end up having to either settle for fewer eggs for freezing or undergo multiple rounds to collect enough eggs to have on hand for later implantation. As you can imagine, those costs can creep higher and higher the more rounds you endure.
Now, you might be thinking: isn’t 14 eggs a lot? It’s true that eggs retrieved from women under the age of 36 will have a 95 percent survival rate after being thawed. But, not all thawed eggs will become viable embryos and lead to a live birth. The probability of a live birth varies with the age of the woman trying to conceive and the number of mature eggs available. In short, the older the woman, the more eggs required to achieve a high probability of a live birth.
A study in the Journal of Assisted Reproduction and Genetics further supports this point. For example, a woman under 35 will need nine eggs to achieve a 70% chance of having at least one live birth. If you’re trying to conceive in your mid to late 30s, you may need double as many eggs to achieve that same 70% success rate.
The right number of eggs to freeze for your age
Different folks have different reasons for freezing their eggs. Some may be thinking about prolonging their fertility into the future. Others may be freezing some eggs but also hoping to donate some eggs to help others grow a family — something that’s done via our Split program, where you freeze for free when donating half of the eggs to a family that can’t otherwise conceive.
Either way, studies have found that the optimal number of eggs to freeze really comes down to your age. That’s because the number of eggs in the body isn’t the only thing to decrease as you get older — egg quality decreases too, and egg quality is the number one factor in determining whether an egg can eventually result in a live birth.
Here are the number of eggs you’ll want to freeze based on your age in order to obtain an optimal live birth rate:
Should I do multiple egg retrievals?
What happens if you don’t get as many eggs as you had hoped during your egg retrieval cycle?
If you’ve undergone one round of egg freezing and the number of eggs your reproductive endocrinologist retrieved from your ovaries wasn’t as high as you’d hoped, you may want to talk to them about trying again. A fertility specialist can help you talk through all of your options.
There is technically no limit to the number of egg freezing rounds a person can undergo, but it’s not recommended that egg donors undergo more than six cycles. If you’re hoping to split your eggs with intended parents (donating half of the eggs retrieved) as part of our Split Program, you may find that additional retrievals help you provide the optimal amount of eggs for a live birth for you and for the intentend parents too.
The right number of eggs to freeze to have multiple children
If you’re planning to have a big family one day, you may want to look at the number of eggs it’s recommended you freeze to achieve one live birth and talk to your Reproductive Endocrinologist (REI) about freezing more eggs.
As we shared above, a woman under age 35 will need to freeze about nine eggs to achieve a 70% chance of a successful pregnancy and live birth. If you’re under age 35 now and thinking you might want to use frozen eggs to conceive twice in your future, you will want to freeze closer to 18 eggs.
The number of eggs necessary will increase with your age at time of the retrieval, and the number of children you hope to have via those eggs.
Can frozen eggs guarantee a successful pregnancy in the future?
When trying to decide if you should freeze your eggs, it’s important to know that egg freezing is not an “insurance policy” for your fertility. While egg freezing can take some of the stress of having a baby right now off your shoulders, it is not a guarantee that you’ll have a baby in the future.
Why not? Well, for one, not all the eggs that get frozen will actually be viable. It’s expected that some eggs will not survive the warming process when it comes time to use the eggs. In addition, the chances of the eggs that do survive being successfully fertilized depends on a variety of factors, including how old you were when you froze them (more on this later).
This is not to sway your decision one way or another. Ultimately, only you and your doctor can decide if egg freezing is the right decision for you. But it's important to go in knowing that it’s not meant to be a done deal. As egg freezing has gotten more popular, many companies will gloss over this fact. We don't think that's right and want to be straight with you from the outset.
Freezing your eggs when you’re unsure if you want kids
Perhaps the biggest benefit of egg freezing is that it puts the decision-making power entirely in your hands. Whether you’re freezing your eggs because you want to focus on your career or you’re about to undergo medical treatment that may affect your fertility later on, or you’re waiting to find the right partner, freezing your eggs allows you to preserve some of your fertility independently.
While you might not be sure about having kids today, if you do decide you want kids down the road, especially if you’re in your mid- to late-thirties, having eggs on ice will increase the chances that you’re able to do so.
Know this: most people do not regret their egg retrieval procedure. We looked at five studies on egg freezing. The rates of regret reported in these studies varied, likely due to the sample size, study design, and the follow-up period. However, taken together, these studies suggest that the vast majority of those who freeze their eggs have zero regrets.
There also appear to be factors that reduce the chances of regret, including feeling fully informed beforehand, and getting adequate support during the egg freezing process. In other words, if you take the time to think things through and feel supported throughout the journey, you’re less likely to regret making this decision for yourself.
The egg freezing process: step-by-step
The egg freezing process is about a two-week journey. You will work closely with a Reproductive Endocrinologist (fertility doctor) and the clinic team throughout the process.
Here's a detailed breakdown of what you can expect from start to finish, and beyond:
- Ovarian stimulation: You'll take hormone medications to stimulate your ovaries to produce multiple eggs, and have multiple monitoring appointments and blood tests to see how the eggs are maturing.
- Egg retrieval: Your eggs will be retrieved through a minor surgical procedure using ultrasound guidance.
- Vitrification: Your eggs will be rapidly frozen using a technique called vitrification, which helps preserve their quality.
- Storage: Your frozen eggs will be stored in a secure facility until you're ready to use them.
- Thawing and fertilization: When you're ready to conceive, your eggs will be thawed, fertilized with sperm (either your partner's or a donor's), and transferred to your uterus.
Will egg freezing hurt my future fertility?
Egg freezing actually rescues all the other eggs that your body would otherwise allow to die during a normal menstrual cycle. So the process of egg freezing doesn’t take anything away from your egg reserve, it actually helps you save some extra eggs! And since during each cycle, your body goes through the ovulation process again with a new set of competing eggs, your chances of getting pregnant unassisted in the future also aren’t affected by egg freezing.
What egg freezing does do is give you additional options for if and when you’re ready to start growing your family.
Is egg freezing safe?
Like any other procedure, there are risks and side effects when freezing eggs, including risks of anesthesia, bleeding, pain, and infection. Thankfully, the majority of people who go through with it deal with side effects for a few days at most. When it comes to the ovaries themselves, they generally recover quickly. The overall data indicate that the potential risks of surgical complications from egg retrieval are generally very small. However, in people with a history of endometriosis, pelvic inflammatory disease, pelvic adhesions or previous pelvic surgery, the risks are slightly increased so make sure to speak to your doctor about your medical history if you fall into any of these categories.
Egg freezing vs embryo freezing
There’s one major difference between freezing eggs and freezing embryos. When you freeze your eggs, they stay unfertilized. We all know that to make a baby, you need an egg and a sperm because each of them provides half of the material needed. On its own, an egg can’t function (and neither can a sperm).
An embryo, on the other hand, is an egg that has already been fertilized by a sperm. Once they combine, the egg and sperm become a single cell. Over the next three to four days, the embryo divides several times, going from one to two to four to eight cells, and so on until it reaches the blastocyst stage and is ready to be frozen. Once an embryo has developed, there’s no going back– that is, there’s no way to turn that embryo back into a separate egg and sperm.
If you don’t know who you want to have children with, then freezing your eggs may be the best approach. This option gives you the freedom to hold off on thinking about having a baby until you’ve met someone or are ready to choose a sperm donor.
On the other hand, if you are currently with a partner who you know you’d like to have children with but now isn’t the right time, then frozen embryos might be the way to go with the goal of a future embryo transfer. The caveat here is to be 100% certain—stars like Sofia Vergara and more recently, Anna Kendrick, have run into trouble after freezing embryos with partners they didn’t end up with.
Read more in Should I Freeze Eggs or Embryos?
Cost of egg freezing
The question of how much does it cost to freeze your eggs will come down to a few factors. These include the number of cycles you undergo to retrieve eggs and how long you keep the eggs in storage. Overall, the typical egg freezing can cost anywhere from $10,000 to $20,000 for one cycle plus the cost of storage fees.
Another option? Freeze by Co offers women a chance to freeze their eggs for free when they donate half of the retrieved eggs to a family that can’t otherwise conceive. The cost of the entire process, including 10 years of cryopreservation, is fully covered — we think it’s a win-win.
Or, if you want to freeze and store your eggs for your own future use without donating, Freeze by Co offers lower prices on things like consultations and storage, along with access to our community of freezers. We partner with lenders, like Sunfish, to offer you fertility financial resources.
Learn more about egg sharing
Egg sharing programs exist worldwide to help make fertility care more accessible. Egg sharing is when a woman undergoes an egg retrieval, and some of the resulting eggs are donated to a family that can’t otherwise conceive.
In Cofertility’s Split program, women can freeze their eggs for free when they donate half of the retrieved eggs to a family who can’t otherwise conceive.
Ask us anything
If you’d like help figuring out when to freeze your eggs, you can contact us for more information. While every woman’s fertility preservation path differs, we can connect you with reputable clinics who can offer basic guidance about when the time is right for you to freeze your eggs during a consultation or dig into specifics by going through a preliminary exam in a provider’s office.
We understand that the timing may not be right for you to start a family right now, but that doesn’t mean it’s too early to start thinking about what choices will be available to you when that time comes. As you can see, a lot goes into preparing for an egg retrieval process. The earlier you consider your fertility, the more options you’ll have.
Whether you decide to freeze or not, we’re here for you to answer any questions or talk through any concerns.
AMH, PCOS, OHSS, WTF?! A Comprehensive List of All the Egg Freezing Terms You Need to Know
A comprehensive list of acronyms, abbreviations, and terms you should know when diving into an egg freezing cycle. Read this, and soon you’ll rattle off egg freezing lingo like a pro
If you just started researching egg freezing, you might feel like you’ve been introduced to a whole new language. Whether clinical in nature or just shortened slang, with egg freezing comes its own terminology. And even if you’ve already educated yourself on what’s involved with egg freezing, chances are, you’ll come across an acronym you’ve never heard of.
Fear not. Below, you’ll find a comprehensive list of acronyms, abbreviations, and terms you should know when diving into an egg freezing cycle. Read this, and soon you’ll rattle off egg freezing lingo like a pro.
Hormones and general fertility
- AMH: One of the first hormones your reproductive endocrinologist will investigate, Anti-Müllerian Hormone is measured early in a woman’s cycle to determine her ovarian reserve. A higher AMH level correlates to a higher ovarian reserve, or in other words, more eggs.
- CD: "Cycle day"—or the day of one's menstrual cycle, with CD1 = the first day of a period. Understanding your cycle length is super important, as it may indicate your most fertile window of dates. It will also help you determine any irregularities to consider as you embark on an egg freezing cycle.
- DPO: "Days past ovulation." In a typical menstrual cycle, women can expect their period at 14DPO.
- Dx: Diagnosis, the medical identification of a condition or issue affecting fertility, which may impact decisions regarding egg freezing and related treatments.
- E2: Estradiol, a female hormone that's produced by ovarian follicles and determines how well a woman is responding to controlled ovarian hyperstimulation with fertility drugs. If you're freezing your eggs, you’ll have several routine monitoring appointments that include ultrasounds and bloodwork that measures estradiol levels. The higher the estradiol, the more follicles that are likely developing and (fingers crossed) the more eggs that may be retrieved.
- FSH: Follicle stimulating hormone, a hormone released from the pituitary gland to stimulate the ovaries or testicles. When getting an initial fertility workup, you'll get tested for your existing FSH. If you're taking FSH as a drug as part of your egg freezing protocol, it's also known in the United States as Follistim, Gonal-F or Bravelle.
- hCG: Human Chorionic gonadotropin, a hormone produced by an implanting embryo. If this hormone is present in a woman's blood, it indicates a possible pregnancy. It can also be given to women undergoing an egg freezing cycle to trigger ovulation right before a retrieval procedure.
- LH: Luteinising Hormone, a hormone released by the pituitary gland to stimulate the gonads (ovaries and testicles). If you're freezing your eggs, you'll have levels of this hormone measured often via bloodwork in order to determine ovulation timing.
- LMP: "Last menstrual period," or the start date of a woman's last menstrual period.
- MII: Metaphase II, the stage of egg maturation where the egg is ready for (hypothetical) fertilization, with chromosome alignment necessary for successful embryo development.
- PCOS: "Polycystic ovarian syndrome," a condition where the ovaries develop many small cysts, which results in irregular periods and ovulation. It can contribute to future infertility, so if you know you have PCOS, regardless of whether you’re freezing your eggs or not, chat with a reproductive endocrinologist to ensure a safe and healthy plan.
- TSH: Thyroid stimulating hormone, a hormone produced by the pituitary gland meant to stimulate the release of thyroid hormone by the thyroid gland. Recent research has suggested that slightly low TSH may associate with fertility challenges.
Egg freezing
- AFC: “Antral follicle count,” a count of the number of small follicles in a woman's ovaries, seen via ultrasound early on in her cycle. Used to measure ovarian reserve, you'll have a lot of these if you're freezing your eggs to monitor how you're responding to ovary-stimulating medication.
- ART: “Assisted reproductive technology,” including any procedure involving egg retrievals and manipulating eggs and sperm outside the body. It includes things like egg freezing, gamete intrafallopian transfer (GIFT), in vitro fertilization (IVF), and zygote intrafallopian transfer/tubal embryo transfer (ZIFT/TET).
- BCP: Birth control pills. If you’re freezing your eggs, your doctor may prescribe these as part of a medicated cycle in order to regulate the timing
- COH: “Controlled ovarian hyperstimulation,” when several follicles mature simultaneously in response to fertility drug treatment. The key word here is controlled. Your follicle growth will be carefully monitored by your doctor, who will adjust your medication protocol accordingly to stimulate or halt further growth.
- ER: "Egg retrieval" — not "emergency room!" An ER will be performed as part of an egg freezing cycle, and may also be referred to as a VOR (“Vaginal Oocyte Retrieval”).
- IM: Intramuscular, a method of injecting medication directly into a muscle. This method is often used for hormone treatments during the egg freezing process.
- OC: “Oocyte Cryopreservation,” which is another term for egg freezing.
- OHSS: “Ovarian hyperstimulation syndrome,” a condition where the ovaries become excessively swollen and painful due to the overproduction of eggs from fertility medications. This is very rare, but can happen.
- REI: "Reproductive endocrinologist," or a doctor who specializes in treating male and female fertility.
- SD1: “Stimulation Day 1,” or the first day of medication administered to stimulate the ovaries for egg production during the egg freezing process.
- SQ: Subcutaneous (also abbreviated as SC), a method of injecting medication into the fatty tissue just under the skin, commonly used for administering fertility hormones during an egg freezing cycle.
- TVUS: “Transvaginal Ultrasound,” an imaging technique used to visualize the ovaries and follicles internally, providing information about egg development and ovarian health. If you’re undergoing an egg freezing cycle, you’ll have a lot of these, but they are quick and painless.
Egg donation
- DE: “Donor eggs,” or eggs provided by another woman to be fertilized with sperm and transferred to the uterus of an intended parent or gestational carrier.
- IP: “Intended parent,” which is a person who becomes the legal parent of a child born through third party reproduction.
If you’re feeling totally overwhelmed by all that’s involved with egg freezing, we’ve got you covered. Take our quiz to see how you may qualify for our more accessible egg freezing opportunities, including our Split program, through which you can freeze your eggs for free when you donate half to another family who can’t conceive.
We’re wishing you the best of luck on your egg freezing journey!