egg freezing

The human papillomavirus (HPV) is the most common sexually transmitted infection (STI) in the United States. In fact, according to the Centers for Disease Control and Prevention (CDC), HPV is so common that “nearly all sexually active men and women get the virus at some point in their lives.” With at least 150 types of HPVs that we know of, it’s no wonder that 79 million Americans have at least one type. But fear not! 

While it’s true that some STIs can lead to infertility, there’s no need to freak out in the case of HPV. HPV on its own shouldn’t affect your ability to conceive. However, because HPV is often asymptomatic (meaning there aren’t any obvious signs or symptoms), it’s also one of the least treated STIs. Most of the time, that isn’t a big deal. But depending on the type of HPV someone has, there can be an increased risk of developing cancer or precancerous cells on the cervix, which do require treatment. The treatments to remove these abnormal cervical cells can, in turn, affect fertility—this is when discussing fertility if you have HPV becomes really important so let’s talk about it.  

What is HPV and what causes it?

We’re gonna back up for a second here and explain the basics of HPV. HPV is actually an umbrella term for a group of over 200 related viral infections that affect the outer skin layers of the genitals, mouth, hands and feet. So, while transmission can happen without sexual intercourse, the vast majority of HPV infections are the result of unprotected sex.

In these cases, you can get HPV by having vaginal, anal, or oral sex with someone who has the virus but it’s most commonly spread during vaginal or anal sex. It also spreads through close skin-to-skin touching during sex. A person with HPV can pass the infection to someone even when they have no signs or symptoms.

Because of this, if you’re sexually active at all, you can get HPV—even if you’ve had sex with only one person. You can also develop symptoms years after having sex with someone who has the infection. This is why doctors usually can’t tell you when you might have gotten it.

Types of HPV and treatments

Of the many types of HPV, only some are of actual concern and could therefore affect fertility, either due to the virus itself or the treatments used to manage it. Low-risk HPVs mostly cause no disease and typically go away on their own within 2-3 years. However, a few low-risk HPV types can cause warts on or around the genitals, anus, mouth, or throat. High-risk HPVs can cause several types of cancer. There are about 14 high-risk HPV types including HPV 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68. Two of these, HPV16 and HPV18, are responsible for most HPV-related cancers.

As mentioned earlier, most HPV infections don’t cause cancer. Your immune system is usually able to control HPV infections so they don’t progress to cancer. However, high-risk HPV infections are more likely to persist and can eventually cause cervical cancer. In these cases, the immune system is not able to control the HPV infection and as the high-risk HPV infection lingers for many years, it can lead to abnormal cell changes that, if untreated, may worsen over time and become cancer.

If your doctor decides that they need to remove abnormal cells, they’ll use one of the following treatments:

• cryotherapy, or freezing and eliminating the abnormal tissue
• a cone biopsy (conization) to remove part of the cervix
• a loop electrosurgical excision procedure (LEEP), which involves removing cells with a wire loop that has an electrical charge

We’ll talk more about how these procedures can affect your fertility later on.

How does HPV impact fertility?

While most HPV infections clear up on their own (and rarely make themselves known through noticeable symptoms), the infections that persist can have a negative impact on fertility for all genders—either due to the infection itself or the treatments used.

Fertility risks associated with HPV include:

• Damage to the cervix via HPV itself or the treatment used to remove affected tissue from the cervix
• Decreased ovarian reserve
• Damage to sperm or parts of the male reproductive system

HPV and cervical function

First and foremost, HPV can damage the cervix directly over time if left untreated. This is why it’s so important to get those annual exams and routine pap smears with HPV testing! Most of the time, testing is the only way to know for certain whether a person has HPV or not. Once HPV has persisted for a long time or is getting more severe, it’s time to remove abnormal cells with one of the procedures mentioned earlier–cryotherapy, cone biopsy, or a LEEP. These procedures can most notably affect your ability to reach full term in a future pregnancy but this depends on several factors including how large and deep the area to be treated is.

In all cases, cell removal can change your body’s cervical mucus production. The procedures may also cause stenosis, or a narrowing of the opening of the cervix. This can slow down sperm and make it harder for an egg to get fertilized. Cones and LEEPs can also cause the cervix to weaken. While this won’t cause infertility or difficulty getting pregnant, it can lead to cervical insufficiency, which can cause your cervix to painlessly open and thin before your pregnancy has made it to term, and lead to a preterm delivery.

HPV and ovarian reserve

There have been several interesting studies about HPV and ovarian function but overall the literature is a bit of a mixed bag. Overall, research has suggested that HPV infection may be associated with a higher rate of spontaneous loss or underdevelopment when undergoing IVF. One study that compared HPV positive and HPV negative people found that a decreased ovarian reserve was more common in the HPV positive over the HPV negative group. Another study looked at HPV positive and HPV negative people undergoing IVF and their response to stimulation. No significant difference was seen in the responsiveness to controlled ovarian stimulation in terms of the number and maturity of retrieved eggs or in terms of fertilization rates. Finally, a recent study published this year showed no effect on live birth rates when comparing people with and without HPV.

HPV and its effects on male partners

Several studies have shown a link between HPV and decreased fertility for male partners. In particular, sperm containing HPV has been shown to negatively contribute to both male and couple infertility. One study done in 2011 found that men who had HPV were more likely to have an impairment of certain sperm parameters, like motility. This was confirmed in another study done in 2015. On top of that, if sperm containing HPV fertilizes an egg, there may be an increased risk of early miscarriage.

Can I freeze my eggs if I have HPV?

The good news with all of this is that an HPV diagnosis alone should not affect your ability to get pregnant or to freeze your eggs. Most fertility specialists will require an up to date pap smear and HPV test as part of their evaluation and you’ll usually be allowed to continue with the freezing process as long as the HPV is low-risk, since those cases are expected to clear on their own.

If you do have a high-risk HPV, you’ll need to discuss those results with both your OB/GYN and your fertility doctor to figure out what next step is right for you. Depending on the specific HPV strain, if there are any lesions and how advanced they are, your doctor will recommend continuing with egg freezing or delaying until after treatment. 

If there are precancerous cells in the cervix, minor treatment through cryosurgery or LEEP will be necessary and this is almost always recommended before trying to get pregnant or undergoing any other fertility treatments, including egg freezing or IVF. For the most part, these procedures don’t affect reproductive potential though and most people go on to have healthy pregnancies once they’ve recovered.

Risks and benefits of egg freezing with HPV

The main risk of freezing with HPV is the concern for a lower yield and the quality of eggs retrieved. As mentioned before, some studies have shown that HPV does have an effect on ovarian reserve but others have shown little to no differences in IVF outcomes. There are also so many additional factors that affect a person’s fertility. Your provider is going to be the best person to tell you whether your case warrants clearing the HPV before moving ahead with egg freezing. The benefit of egg freezing with HPV is that you’re taking a proactive step to preserve your future fertility. Whether your HPV is low- or high-risk, whether you require treatment or not,  you’ll know you’ve safeguarded your options.

Can I donate eggs if I have HPV?

The donor egg screening process will vary somewhat from clinic to clinic but here at Cofertility, our goal is to be as clear as possible about what this involves. All potential donors will be assessed in terms of their age, AMH levels, medical and family history, psychological and physical health. Making sure your pap smear and HPV testing are up to date is included in this process. 

HPV won’t automatically disqualify you from becoming an egg donor since it’s not transmittable through your eggs. However, as mentioned before, this will depend on which HPV type, whether it’s low or high-risk, and whether there are any precancerous or cancerous lesions found during the screening process. For a full list of disqualifications for egg donation through Cofertility, click here. 

Conclusion

The takeaway from all of this at the end of the day is that preventive care is king! Protecting yourself from HPV by getting vaccinated and making sure to get your pap smears on time can not only decrease your cervical cancer risk (which is a pretty good reason all on its own) but it can also lower your risk for preventable pregnancy or fertility concerns down the road. 

While there’s still more research to be done on the effects of HPV on fertility in all genders, it can safely be said that discussing HPV and fertility with your healthcare providers should be at the top of your list. This is especially true if you have HPV and end up requiring more invasive management—your providers can help you make a plan about your fertility future before any treatments begin.

Egg freezing and HPV can be confusing individually so you’re not alone when it comes to questions and concerns around both topics and how they affect each other. Freeze by Co is here to help you every step of the way. With our Split program, people between 21 to 33 years old have the chance to freeze their eggs for free! After a “Split” cycle, you would donate half of the eggs retrieved to a family that’s trying to conceive and freeze the remaining half for yourself. 

If you’re over 34 or not interested in donating half the eggs retrieved, you can still participate in the Keep program up to age 40. You would be able to freeze your eggs and keep them all for yourself, on your timeline while having access to an additional valuable resource in our support community. Our private, online community allows you to engage with other people freezing their eggs at the exact same time! 

Regardless of which path you choose, our Freeze by Co team and medical experts will be there to guide you through the process as we work to keep your family-building options on the table.

Donating your eggs is an extraordinarily generous act. As an egg donor, you have the potential to help a family struggling with infertility or a same-sex couple realize their dreams of parenthood. But the decision to donate eggs is not one to be taken lightly, and it's natural to want the support and understanding of your family as you embark on this journey.

If your partner is unfamiliar with the egg donation process, they may have numerous questions and concerns. Some of the most common questions revolve around the medical risks involved, potential contact with the intended parents (IPs), and the timeline of the whole process. Here's a guide to help you address these concerns.

Should I tell my partner/boyfriend/spouse I want to donate my eggs? 

While it is absolutely within your right to keep this information private, there are considerations that might sway you toward opening up about it.

First, it may be hard to hide. The egg donation process involves medical appointments, injections, and potentially some down time after the egg retrieval. It could become difficult to keep these aspects concealed, especially if you and your partner share many aspects of daily life. From a practical standpoint, hiding the process may add unnecessary stress or complications.

Second, you might want their support. Sharing the decision with your partner can foster open communication and enable emotional support throughout the process. It provides an opportunity for your partner to understand your motivations and to be part of the experience, even if only as a listener or a helping hand.

Your partner's reaction to this decision might also provide valuable insights into the relationship's dynamics. If the response is dismissive, excessively critical, or unsupportive, it may be a red flag that prompts further reflection on compatibility and shared values. Conversely, a supportive partner's response can strengthen the relationship, building deeper trust and empathy.

While there is no right answer, one thing is for certain, your decision to donate is yours and yours alone, and so is your decision to tell them… or not. This means you are the one who can best make this decision.

Read more in: Should I Tell People I'm Donating My Eggs? 

Common questions partners may have

What is the medical risk?

Egg freezing is considered a safe procedure. In a single egg freezing cycle, the risk of a serious adverse event is under 2.5%. Severe OHSS accounts for the majority of complications, occurring in 0.1-2% of cycles. The risk of other acute complications, including pelvic infection, intraperitoneal hemorrhage, or ovarian torsion, is small (<0.5%). That being said, many women do experience minor side effects – like bloating, constipation, nausea – from the medications and egg retrieval.  Side effects are typically mild and short-lived.

Egg donation requires a series of hormone injections to stimulate the ovaries into producing multiple eggs during a single cycle. You can assure your partner that these medications are prescribed under the careful supervision of a fertility doctor.

The egg retrieval process itself is a minor surgical procedure done under sedation, so you won't feel anything during the procedure. Post-procedure discomfort is typically minimal and can be managed with over-the-counter pain relievers. 

You can remind your partner that all steps of this process are carefully monitored by experienced, board-certified fertility doctors who prioritize your health and safety above all.

Will you be freezing eggs or embryos and why?

If you’re in a relationship with a biologically male partner, they may be wondering if you are going to freeze embryos or eggs. 

While it’s true that thawing success rates can be slightly higher for embryos than eggs (at a 95% survival rate vs 90% for eggs), the downside is that once an egg is fertilized with sperm, there’s no going back, so freezing eggs instead of embryos will give you more options down the line. 

We know, this might be a little bit of an awkward one to bring up with your partner, but it might come up at some point, so the best you can do is be prepared with the facts.

Read more in:

• Should I Freeze Eggs or Embryos?
• We Asked Four Women: Did You Freeze Eggs or Embryos?

Will egg donation impact your ability to have kids in the future? 

Egg donation, which is the same medical procedure as egg freezing, won’t lower your egg reserve and it won’t affect your chances of getting pregnant naturally when you’re ready to do so. 

In fact, participating in our Split program – where you freeze your eggs for free when donating half to another family – can actually increase your chances of having a baby down the line because you are preserving younger eggs. 

Who are the parents that need donor eggs?

Many types of families need egg donors to grow their family, including people facing infertility, LGBTQ+ couples, cancer survivors, women with age-related fertility decline, and more. 

Sharing more about the family you are matched with can help humanize the experience.

What will your relationship be like with the intended parents?

The level of contact with the intended parents is highly dependent on the agreement you reach beforehand. Some arrangements are undisclosed, with no information exchanged between you and the IPs. Other arrangements are disclosed, allowing varying degrees of communication and contact, such as the exchange of letters or even face-to-face meetings.

Your choice about the type of relationship you wish to have with the IPs is up to you, and you should assure your partner that you will make the choice that feels right.

Does this mean our future kids will have siblings out there?

Technically speaking, children born from your donated eggs would share a genetic link with you, as well as with any of your existing biological relatives. However, neither you nor your partner would have any legal or parental ties to these children.

A sentiment eloquently expressed by one of our egg donors to her boyfriend captures this nuance: “I view egg donation as an act of helping others realize their family dreams. The children born from my eggs will belong to their own families, not ours. While the connection may be biological, it isn't familial."

What are the legal implications?

Understanding the legal rights and obligations associated with egg donation is important. You can let your partner know that before the egg donation process begins, you will sign a legal contract that outlines the rights and obligations of all parties involved. This includes an agreement to relinquish all parental rights to any children born from the donated eggs. 

How does Cofertility work?

Cofertility’s Split program offers women a chance to both freeze their own eggs and donate half the eggs to a family who cannot conceive otherwise. Every expense associated with the egg freezing procedure —  medications, supplements, travel if necessary, insurance, and 10 years of storage — are completely free of charge. 

Cofertility assigns a Member Advocate to each donor to support her throughout the entire journey. They’ll be there every step of the way as appointments get scheduled and plans for the cycle are made. No question is too small for Cofertility’s Member Advocate team. Plus, Split members have support of our entire community of others going through the same process.

How much time will it take?

The timeline can vary depending on several factors, including your menstrual cycle and the matching process with intended parents. The process begins with an application, followed by a screening process, which can take several weeks. 

Once approved and matched with the IPs, you'll start the ovarian stimulation process, which takes about two weeks. This involves daily hormone injections to stimulate the ovaries. The egg retrieval procedure is scheduled once the eggs are mature, typically after 10-14 days of stimulation. Following the retrieval, you will have a brief recovery period, usually a day or two, to allow any minor discomfort or side effects to dissipate. You will know immediately how many eggs were retrieved and frozen for your own future use. 

In total, from match to retrieval, the process can take anywhere from two to four months.

Will you get enough eggs to use in the future?

Being part of Cofertility’s program means you passed rigorous medical screening, including AMH and antral follicle count, and that our medical team and the doctor performing the egg retrieval believe you are a good candidate for egg sharing. This doesn’t guarantee that you will get a lot of eggs, but it is pretty predictable. 

Furthermore, a UK study of egg sharing amongst IVF patients found that participating in an egg sharing program did not compromise the chance of achieving a pregnancy or live birth for the egg sharer or the recipient.

Summing it up

Your partner’s concerns and questions about your decision to become an egg donor are understandable. They want to ensure your safety and wellbeing, and these are valid concerns.

As you discuss the process, remind them of your reasons for making this choice and assure them of your commitment to understanding and minimizing the risks involved. Encourage them to accompany you to a medical consultation if possible, to provide them an opportunity to hear information directly from professionals, and to ask any questions they may have.

Your act of egg donation could bring immense joy to a family longing for a child. It's a beautiful decision, and having your partner’s understanding and support will undoubtedly make the journey even sweeter.

Read more:

• I'm a Psychologist: Here's How to Talk to Your Partner About Donating Your Eggs
• How To Talk To Your Family About Donating Your Eggs
• How to Support Your Partner Through the Cofertility Split Program
• Does Donating Eggs Affect Your Fertility?

At Cofertility, we pride ourselves on guiding our members through the journey of egg donation, ensuring a supportive, transparent, and ethical process for all parties involved. One aspect of this process involves helping our members understand the various terms used within the realm of egg donation, and pros and cons of each type of disclosure status. 

Each relationship is unique and depends on both the desires of you and family, as well as what’s best for any future donor conceived children. 

This guide is meant to aid you in making informed decisions that align with your personal beliefs, comfort level, and the best interest of any potential donor conceived children.

Let’s dive into the terms:

• Anonymous egg donor: an outdated term used to describe someone whose identity is not shared with the family. In today’s age of social media and genetic testing, we think “anonymous” is a misnomer. 
• Non-anonymous egg donor: an outdated term used to describe when an egg donor and intended parents have each other’s contact information.
• Known egg donor: usually used to describe an egg donor who knows the intended parents, like a family member or friend.
• Unknown egg donor: an egg donor that does not know the intended parents, and vice versa.
• Disclosed donation: the intended parents and egg donor exchange contact information and communicate directly. This does not mean they have an ongoing relationship, just that they have the names of one another. 
• Undisclosed donation: the intended parents and egg donor do not exchange contact information.
• Open ID: the intended parents and egg donor do not exchange contact information, but the egg donor agrees to have her identity disclosed to the child born from her donation once the child reaches a certain age, typically at 18 years.
• Identity-release: another term for open ID.

The fallacy of the "anonymous" egg donor

Back in the day, egg donations were often declared "anonymous," meaning the identities of the egg donor and the intended parents were kept secret from each other. However, the concept of total anonymity seems antiquated in an era of advanced genetic testing and omnipresent social media. So, if someone promises you complete anonymity, treat that claim with skepticism.

Read more about why we don’t believe in anonymous egg donation.

Disclosed and undisclosed egg donation

Disclosed and undisclosed are the terms we prefer to use at Cofertility to describe the two types of disclosure agreements possible. 

In a disclosed donation with Cofertility, you and the family will exchange contact information and can communicate directly. We highly encourage this model as it promotes transparency and aligns with feedback from donor-conceived community.

In an undisclosed donation, you do not exchange contact information and only communicate via Cofertility. Although we recommend disclosed donations, we respect the individual's choice for undisclosed donation after understanding the potential implications for donor-conceived child.

Regardless of your donation disclosure status being disclosed or undisclosed, you may choose to meet the family during the matching period without exchanging contact information. 

The scope and degree of communication in a disclosed donation (both during and post-match) is what both parties make of it and can be outlined in your legal agreement. Communication can range from sharing an annual holiday card to direct, regular communication between you and the family. 

Your disclosure status does not necessarily dictate the relationship with the family or child. For instance, you may opt for a disclosed donation, where you share contact information, but decide against maintaining regular communication.

Undisclosed egg donation with Open ID

For those who choose an undisclosed donation, open ID (sometimes called identity release) is an option. This model allows any child resulting from the donation to receive your contact information once they reach a certain age, typically 18 years. 

This option safeguards the child’s right to learn about their genetic history, should they wish to. The open ID agreement is often structured based on the comfort and consent of all parties involved and takes into consideration the best interest of the donor conceived child.

Disclosed egg donation arrangement has varying degrees of interaction 

Here are a couple of questions you might consider asking yourself in defining your preferences for a disclosed donation:

• How do I feel about the possibility of the intended parent’s future child reaching out to me when they turn 18 or another age? 
• Do I envision myself forming a lasting connection with the intended parents and their child, or am I more comfortable with a limited interaction?
• Am I open to receiving or sharing updates, and if so, what frequency feels right to me?
• What boundaries or personal limits do I want to establish regarding communication and relationship with the intended parents vs. their child?
• Can I envision scenarios where my level of involvement might change over time?

You don’t have to have all of the answers. It is only natural that your needs and preferences will evolve with time. To help you gauge your current preferences, consider the following scenarios illustrating a disclosed donation at various degrees of engagement.

Lower engagement scenarios:

• Medical updates only: You are comfortable with exchanging contact information but agree with the intended parents not to send or receive any social updates. The intended parents can reach out directly with any medical/health questions, and you agree to inform the family of any new medical information that arises.
• Occasional updates: You and the intended parents agree to exchange occasional updates through email, letters, or text. An example of this is receiving an annual holiday card. This approach maintains a sense of connection without imposing an ongoing commitment.

Moderate engagement scenarios:

• Virtual check-ins: You and the intended parents opt for occasional video calls, perhaps once or twice a year. This allows for more personal interaction and a chance to see the child's growth, fostering a stronger bond while keeping the relationship primarily digital.
• Scheduled visits: You and the intended parents might agree to an in-person visit, perhaps once every few years, providing an opportunity for face-to-face interaction. 

Higher engagement scenarios are rare, and generally occur between donors and families with a pre-existing relationship. That being said, in some cases, if you (and the parents) want more involvement, it is possible. 

The power of choice: respecting cultural preferences & unique circumstances

While we advocate for disclosed or undisclosed open ID donations, we respect the cultural needs and unique circumstances of those who prefer undisclosed donations. At Cofertility, we strive to connect egg donors with research and experts, aiding in informed decision-making, and respecting cultural considerations.

Understanding these terms and the principles behind them can make your journey through egg donation smoother and more transparent. We are here to support and guide you, ensuring a process that honors all parties involved.

Learn more about becoming an egg donor:

• Does Donating Eggs Affect Fertility?
• Will I Regret Donating My Eggs?
• Want to Donate Your Eggs? Tips on Talking It Over with Your Partner

One of the most commonly asked questions we hear from people considering freezing their eggs is if they’ll gain weight during the process. Hey, we get it — it’s a fair question, and while there have been tons of advancements in the egg freezing process, there’s still lots of misinformation out there about it all. Through a comprehensive exploration of the egg freezing process, hormonal shifts, medications, and lifestyle aspects, we’re here to set the record straight about weight gain and egg freezing. 

A closer look at the egg freezing process

Before we jump into potential weight implications of the egg freezing process, it’s essential to understand what that process actually entails. Egg freezing revolves around controlled ovarian stimulation, which basically means taking daily hormonal medications for about 10-12 days to stimulate your ovaries to produce more eggs than usual in a single cycle. Right before you ovulate, when those eggs are at peak maturity, a reproductive endocrinologist will retrieve those eggs while you’re under anesthesia. 

In egg freezing, mature eggs are collected, frozen, and stored for your own potential future use, whereas in egg donation, the retrieved eggs are contributed to assist those who need help from an egg donor to grow their family — including gay dads, those with infertility, cancer survivors, and more. Whether you’re freezing your eggs, donating them, or both via our Split program (where you freeze for free when donating half), the stimulation process may cause concerns about potential weight changes due to hormonal shifts and medications. If this is you, you’re in the right place, and we’ll explain it all.

Dispelling weight-related myths: the what and the why

While scientific studies about this subject are limited, most fertility doctors say that, while some weight gain can be a side effect during the egg freezing process, it is unlikely for noticeable weight gain to persist beyond the retrieval cycle. It’s possible to experience slight weight fluctuations during the retrieval cycle, but these changes are typically attributed to factors like temporary fluid retention and abdominal bloating rather than significant fat accumulation. 

Not everyone experiences weight change during the egg freezing process (you could actually lose weight if you’re stressed about the experience for one reason or another and don’t have an appetite), but for those who do, it is not usually substantial or enduring.

Egg freezing medications

Some of the medications involved in your egg freezing protocol can also play a role in minor weight changes. The controlled ovarian stimulation process involves the administration of hormonal medications, primarily follicle-stimulating hormone (FSH), and luteinizing hormone (LH). These medications are crucial for encouraging your ovaries to develop more mature eggs during that cycle. But because these medications can influence appetite and metabolism regulation, this could lead to small weight fluctuations. 

Once you stop taking these medications, any fluctuations resulting from temporary fluid retention will likely dissipate, and these effects are generally transient. 

Lifestyle factors and their impact

Beyond medications, lifestyle factors also play a role in potential weight fluctuations during an egg freezing cycle. But regardless of your weight, we want you to feel your best throughout your egg freezing cycle. 

Nourishing your wellbeing

Egg freezing or not, a well-balanced diet rich in nutrients supports your body's overall functioning. Incorporating whole foods, lean proteins, whole grains, fruits, and vegetables fosters a sense of wellbeing and provides energy throughout the egg freezing process. But in addition to helping you feel good, eating a balanced diet may have a positive impact upon your egg freezing cycle itself. And certain foods rich in specific nutrients may actually impact your egg quality. 

For more on what to eat if you’re freezing your eggs, click here.

Rest and stress management

Ensuring adequate rest is vital during the egg freezing journey. Your egg freezing medications may influence your energy levels, underscoring the importance of listening to your body's cues. Stress can also influence weight fluctuations (in either direction), making stress management an essential aspect of wellbeing during the egg freezing process. 

Prioritizing rest allows your body to recover, and if you’re trying to maintain a stable weight, it can help support that. Our recommendation? Block off some time, load up on shows to watch, plan some cozy nights, and take egg freezing as an excuse to just chill (if you can). Your egg freezing cycle might also be the perfect time to finally download that meditation app you’ve been planning to try.

Egg freezing and BMI

While we’re on the subject of weight gain and egg freezing, you may be wondering if your weight itself plays a role in predicting your cycle outcomes. There’s a lot of conflicting research out there about this, but when it comes to egg donation in particular, fertility clinics often do have BMI limitations in place. For egg freezing, you may be subject to similar BMI requirements as set out by clinic partners, but it is typically more flexible than if you are donating eggs to another family. 

The more you know

To sum it up — yes, sometimes people gain a little weight during the egg freezing process (and other times they lose a little weight). But it’s usually not a noticeable change given how the egg freezing cycle lasts under two weeks. If you have specific concerns related to weight gain during egg freezing, we encourage you to consult with your fertility doctor who can provide personalized guidance based on your weight and health history.

As you think through your options, we encourage you to explore our quiz to see which of our accessible egg freezing programs you may qualify for. 

With our Split program, members who qualify based on clinic criteria can freeze their eggs entirely for free when they donate half to a family that can’t otherwise conceive.

Through our Keep program, members self-fund their egg freezing journey and keep the entire egg yield for themselves, with discounts and support from our team every step of the way.

With both programs, members also get exclusive access to our members-only community, where they can connect with others going through the egg freezing and donation processes at the same time and lean on each other for support and encouragement.

To see which programs you qualify for and start your journey today, click the link below to take our free, two-minute quiz.

Of the many decisions you have to make when freezing your eggs is if you want to freeze eggs or embryos. The answer for you may be influenced by myriad factors such as age, relationship status, or your fertility goals. 

We’ve written about making this decision here. But we wanted to make it a little more personal. To shed some light on this topic, we interviewed four of our egg freezers. Two of them opted to just freeze their eggs, while the other two chose to fertilize those eggs and freeze embryos. 

Through their stories and perspectives, we explore the motivations behind their decisions, the pros and cons they considered, and the impact this choice has had on their lives.

Only first names are being used to protect the privacy of these egg freezers. 

Empowering the future with frozen eggs

Sarah, a successful career woman in her early 30s, decided to freeze her eggs. She emphasized the sense of empowerment and choice it provided her, stating, "I never even considered freezing embryos. I do have a boyfriend, but there’s no ring on my finger. And to be honest I have no idea if he’s the one I want as the father of my future children. Freezing my eggs allowed me to feel less pressured to rush my current relationship."

Mia, a woman in her early 40s, carefully considered her options and decided to freeze her eggs as well. While we at Cofertility support all paths to parenthood, Mia decided against becoming a single-mom-by-choice for now. She explained, "I discussed the idea of using donor sperm with my doctor, but ultimately opted against it…While there are uncertainties, I value the ability to choose my path and have the freedom to explore different possibilities down the road." 

Embryo freezing as a family building strategy

Nazanin, in her late 20s, chose to freeze embryos with her partner. Reflecting on their decision, she shared, "Having frozen embryos gives us peace of mind and a tangible plan for our future. I think it brought us closer as a couple and gave us both a sense of security knowing that we have already taken steps towards building our family." 

Olivia, a woman in her mid thirties, shared her perspective on freezing embryos, stating, "I’m married so it was a no-brainer for us to freeze embryos. My husband and I are both running startups, so now is just not the right time for us to have kids. But we know we want them some day, and chose to freeze embryos to give us a higher chance of success when we are ready."

Pros and Cons of Egg Freezing and Embryo Freezing:

Both egg and embryo freezing offer unique advantages and considerations. Egg freezing provides women with the most flexibility, as Sarah explained, "I valued the freedom to make choices on my own terms without the pressure of finding a partner right away." However, when freezing eggs, there is the uncertainty of successful fertilization and embryo development.

On the other hand, embryo freezing provides people with ready-to-use embryos, increasing the chances of a successful pregnancy. Emily emphasized this advantage, saying, "Having frozen embryos gives us a higher sense of certainty and a stronger foundation for our family-building journey." As Olivia highlighted, "Embryo freezing involves joint decisions and a deeper level of commitment."

Summing it up

The decision to freeze eggs or embryos is one you’ll have to decide before starting your egg freezing treatment, Nazanin, Mia, and Olivia's stories provide insight into the different motivations and considerations that led them to their chosen path. 

If you feel stuck on this decision, consider talking to your therapist or others who have gone through the process (if you freeze your eggs with Cofertility, you’ll get access to our online community). 

Freeze your eggs with Cofertility

Cofertility is a human-first, tech-enabled fertility ecosystem that provides people agency over if, how, and when they have babies — today or someday. We have two programs for egg freezers:

1. Our Split program offers women a chance to freeze their eggs (or embryos) for free when donating half of the eggs retrieved to a family who cannot otherwise conceive. If you qualify for the program and decide to donate half of your retrieved eggs, every expense associated with the egg freezing procedure —  medications, supplements, travel if necessary, insurance, and 10 years of storage — are completely free of charge. We don’t even need a payment or credit card up front, as the family you match with covers all the expenses.
2. Our self-pay Keep program allows women to freeze their eggs and keep them all for their future use. Through Keep, we offer our members partnerships and discounts to lighten the financial load of egg freezing, as well as access to our member community.

In either of these options, you have the option to freeze eggs or embryos. 

Ready to learn about more affordable (even free!) egg freezing with Cofertility? Fill out this quick quiz to learn about our accessible egg freezing options and see if you qualify for our programs — it only takes one minute.

Wanting to donate your eggs to help others grow their family is an incredible act to do for another person or couple. And something that should be fully researched, understood and not be taken lightly. Aside from the physical and medical side effects, you should also be aware of any potential emotional and psychological and legal ramifications of donating your eggs. 

How egg donation works

Each egg donation requires psychological and medical screening to determine if certain requirements are met in order to become an egg donor. The actual process does not begin until you are matched and legal paperwork has been completed.  Once that happens, you will attend approximately six to eight visits to the medical clinic over a two-week period. You will typically be getting ultrasounds to check how many eggs are being produced and how you are reacting to the hormones. These hormones will be self-injected several times a day for seven to 10 days. These hormone injections are given using a small needle under the skin of your abdomen. The hormone injections stimulate your ovaries to enlarge and produce eggs, more than are typically produced during your natural cycle which is typically one egg per cycle. 

On the day of your retrieval, you will be put under sedation. Using an ultrasound guided needle your doctor will vaginally insert the needle into each mature follicle to retrieve each egg. Day of and day after retrieval you may need to take time off from school or work to recover. But because the process is minimally invasive, you should be back to normal within a few days. 

Read more in How Does Egg Donation Work?

Biological vs. legal parenthood

Because you are donating a piece of your genetic material, it is important for you to understand that you are biologically related to any child that is born from your eggs. And it is important for you to understand that your future children will be half siblings with the children born from the eggs that you donate. 

However, being a biological parent is different from legal parenthood. You will not have any legal responsibilities for the child born from your donated eggs because you will sign a legal document surrendering any and all parental rights.  

Legal parents have a family relationship to the child by law. This relationship does not need to be formed by blood or DNA, for example in the case of an adopted child. Even though the resulting child is very much the child of the recipients,  it’s important to understand that you are genetically related to that child. If down the road you did a DNA test and the child did a DNA test, the relationship would read “biological mother.” 

Type of relationships

Depending on the type of relationship you have with the recipients of your eggs, you can have a relationship with the child born from your donated eggs, if you and the recipients agree to that type of relationship.  The different types of relationships include, disclosed, undisclosed and open ID. In a disclosed donation, you will exchange contact information with the recipients and communicate directly. This does not mean you will have an ongoing relationship into the future. It just means that both parties will have each other's names and contact information.  

In an undisclosed donation you will not exchange contact information with the recipients and will not communicate directly. Finally, with an open ID you again do not exchange contact information, but you legally agree to have your identity disclosed to the child born from your donation once the child reaches a certain age, typically at 18 years. So, once the child reaches the agreed upon age, they can contact the clinic, bank or attorney and will be able to contact you. 

Conclusion

Women are born with all of their eggs. And as time goes on, the quality and quantity dramatically declines, specifically after the age of 35.  It can be devastating when a woman is ready to start a family, only to find out that it’s too late.  So the only way a family will ever be formed is by  having access to donor eggs. Same is true for gay couples or single men. So deciding to donate your eggs can completely change the trajectory of someone’s life; from dreaming of being a parent to actually being a parent. As a donor, it is your job to be fully informed of all the potential legal, medical, emotional and psychological side effects of donating your eggs. Ask all the questions until you feel fully ready to donate. 

Egg donation with Cofertility

At Cofertility, we are striving to be the best place to be an egg donor (or what we call, a Split Member). We offer a supportive and transparent process that empowers donors to make informed decisions about their egg donation journey.

With our innovative approach, donors get to keep half of the eggs retrieved, plus:

• Free storage of their own eggs in cryopreservation for up to 10 years
• Coverage of all medical costs for the egg donation process
• Connection to the Cofertility community for support all along the way and after too
• The ability to work with the intended parents to decide together what your relationship will look like

If giving your eggs to intended parents sounds like something you would like to do, you may be able to qualify for the free egg freezing process and have your donation process covered too.

Find out more about Cofertility, and take our quiz to see if you qualify for Split!

We believe that every donor deserves to have a positive and empowering experience, and we are committed to making that a reality. That’s why Cofertility was named one of the Best Egg Donor Programs by Egg Donor Connect.

Amanda Goetz, marketing genius and the founder of House of Wise (which was successfully sold) has an inspiring career background that includes five years at The Knot Worldwide as Vice President of Marketing. But aside from her professional accomplishments, Amanda's personal life and decisions make her story even more compelling. Recently, she shared her journey of freezing her eggs with us, a decision made during a tumultuous period in her life.

Egg freezing amidst chaos

Amanda's decision to freeze her eggs came at a crucial time when her life was already filled with change and uncertainty. Following a divorce at the age of 32, with three children under age four, Amanda recognized that her present self was not equipped to make permanent decisions about her future family planning.

"We retrieved 19 eggs at age 32," Amanda recalled. Though she already had three children, Amanda chose to freeze eggs, not embryos, as she was still casually dating and wasn't in the right headspace post-divorce to make this decision with a partner.

Facing challenges head-on, like everything else in her life 

Amanda's egg freezing journey was not without its hurdles. Her process coincided with the global COVID lockdown, and she was inundated with hormones just as the world seemed to be ending. The societal challenges were significant, too, with questions about why she was freezing her eggs when she already had three children. Amanda's honest response reflected her wisdom: "I just knew that current Amanda wasn't in a place to make decisions for future Amanda, and I wanted to retrieve eggs as young as possible."

The downsides? Amanda faced discomfort, weight gain, and a disruption in her workout routine, leaving her feeling bloated and uncomfortable. Navigating relationships during this period proved challenging as well, with a significant other becoming too freaked out to be around, leaving her feeling alone. 

Thankfully, support came in unexpected ways, including a newfound friend on Twitter who was undergoing the same process. She also credits her therapist who helped her through the process, and a best friend who was there to pick her up after the retrieval. “A support system is key”. 

Reflection and advice

Looking back on her experience, Amanda is confident she made the right decision. She emphasizes that egg freezing is not a foolproof insurance policy, and she wishes she had known more about the survival rates and the likelihood of pregnancy using the frozen eggs.

Her advice to others considering this path is insightful and practical. "It is not a full-proof insurance policy. I think I would have approached it differently if I didn't have children. I would have done multiple rounds and froze several embryos with a donor for extra safety."

Amanda's story is still unfolding, with her frozen eggs still being kept and a decision planned within the next five years. 

Amanda’s experience with egg freezing is something we often see, one filled with emotions, insights, and hard-won wisdom. Her journey contributes to the vital conversation about family building and choice, helping to remove stigma and encourage a more nuanced understanding of this complex decision-making process. 

Her voice stands as a testament to the strength, adaptability, and wisdom that many women must summon as they navigate their unique paths to family planning, even if it happens in different life eras. Her message is clear: planning for the future requires understanding, compassion, and the courage to embrace uncertainty.

Learn more about egg freezing:

• How Many Eggs Do I Need to Freeze?
• How Many Times Should I Freeze My Eggs?
• How to Score Egg Freezing Discounts

As the Co-Founder and CEO of Aavia, an app designed to connect the dots between ovarian hormone health and women's daily lives, Aagya Mathur stands as an icon in women’s health. Recognized by Forbes as one of the top women leading startups that are disrupting health tech, she's not only shaping the industry but also influencing individual lives through her personal choices and advocacy.

Aagya's background in Neuroscience from the University of Virginia, combined with her MBA from MIT Sloan, has laid the foundation for her innovative work. Her past experience in management consulting across healthcare and retail clients further shaped her understanding of women's needs and inspired her to take a proactive approach to family planning.

We got the chance to interview her about her egg freezing experience, so let’s dive in.

The decision to freeze 

"I am lucky to have many older sister figures," Aagya explained, describing the influence of family and friends' experiences on her decision to freeze her eggs. She continued, "Their willingness to be vulnerable and share really opened my eyes to potential hardships. I remember one who explicitly told me – I wish I knew that freezing my eggs was an option when I was younger and that I did it."

At 32, Aagya sought her parents' thoughts and support, forging ahead with a process she knew was right for her. The personal stories and her background in the women's health space empowered her to make an informed decision.

The process: challenges and rewards

Aagya's journey involved meticulous planning and temporary lifestyle changes. She revealed, "I didn’t travel or go out late too much for about a month, and my friends and family showed up for me throughout the process." 

Those moments of support became memorable, with friends and family members showing their support: “It was really special that each night someone would show up for me whether going to go get our nails done or ordering Italian and sitting on my couch.”

They successfully retrieved a number of eggs which are now safely frozen in long-term storage.The hardest part, she recalled, was "Feeling very heavy before the procedure! But it wasn’t too bad."

The first injection was the hardest

A common fear among many who embark on the journey of egg freezing is the shots. Aagya, despite having taken the MCAT and shadowing doctors before deciding not to pursue medical school, shared this apprehension.

"I was most nervous for the first injection!" Aagya recounted. The idea of injecting herself was unsettling and a significant obstacle she had to overcome. But ultimately, she wanted it more than she was afraid of it. 

With trepidation, she administered that first shot, and much to her relief, discovered that her fears were unfounded. "After administering the first shot, it was a breeze! You can't even feel the needle," she exclaimed.

Her experience with the first injection is a metaphor for the entire egg freezing process and, perhaps, for life's challenges in general. Often, the anticipation of an event can be far more intimidating than the actual experience. Once Aagya faced her fear head-on, she found the rest of the process relatively smooth.

Impact on personal and professional life

The timing of the procedure pushed Aagya's plans by a few months, but the experience also illuminated the compassion of her investors. She said, "I was closing a round of funding, and actually it helped bring light to investors who cared for their founders." One investor even sent her a silk eye mask to help with the recovery process after the procedure.

Aagya was dating someone during this whole process, who is now a long-term boyfriend. “I was dating someone at the time and I didn’t expect it to be such a weird topic to discuss. I think we need to keep de-stigmatizing this. I wasn’t planning a family with him - I was just planning.”

 “I wasn’t planning a family with him - I was just planning”

Aagya's entrepreneurial spirit, combined with her unswerving commitment to empowering women, shines through her personal and professional choices. Her decision to freeze her eggs aligns perfectly with her mission to provide women with the tools and information they need to take control of their health and lives.

Looking back and advice for others

Reflecting on the experience, Aagya expressed no regrets: "I am really glad I did it!" Her advice to others considering egg freezing is resolute: "If you’re considering it, take the leap! Even if it’s just as an insurance for a second kid, if you choose to have kids at all."

Her story, woven with insights, courage, and empathy, contributes to the broader narrative of women's reproductive health. Aagya’s contributions to women’s health, her leadership, and her personal journey serve as an inspiration to many, underscoring the importance of empowerment, awareness, and self-care in our lives. Her work with Aavia continues to break barriers and establish connections, highlighting the essential dialogue between health, technology, and personal empowerment.

Learn more about egg freezing:

• I'm Afraid of Needles; Can I Still Freeze My Eggs?
• Should I Freeze Eggs or Embryos?
• The Fearless Journey: Missy Modell on Freezing Her Eggs
• Five Reasons to Freeze and Share Your Eggs with Another Family

More and more people in the US (and the rest of the world) are taking control of their reproductive health and fertility by choosing to freeze their eggs. Whether this is so they can focus on a career, get an insurance policy with coverage for treatments, or because of medical reasons, this has allowed people to delay having children until whenever they’re ready to start a family.

If you’re thinking about freezing your eggs, you probably have tons of questions. In this article, we’re going to focus on a very common question: “How can I increase my chances of success when I freeze my eggs?”

Factors that can affect egg freezing success rates

Before an egg freezing cycle

Let’s start by going through what specific things make a difference in your chances of success before you even freeze your eggs.

Age

Age has been proven by countless research studies to be one of the biggest determinants of egg quality. As a person ages, their eggs are more likely to become aneuploid, meaning they’re genetically “abnormal.” This can lead to issues with both getting and staying pregnant (i.e, higher risk of miscarriages). On top of that, as a person ages, the number of eggs their ovaries contain continues to decrease naturally. Once a person reaches their mid to late thirties, the quality and quantity of eggs starts to go down more quickly. While there is no “perfect” age at which to freeze your eggs, freezing them before you reach your late 30s is considered ideal. 

AMH level

Another important factor is your Anti-Müllerian hormone (AMH) level. This is a simple blood test that is commonly used to tell us a person’s reproductive potential based on the number and the quality of eggs they have left in their ovaries. AMH is released by antral follicles, which are small, fluid-filled sacs in the ovaries that each contain a single oocyte (immature egg). Your AMH level is positively correlated with the number of antral follicles you have in your ovaries. Simply stated, the more follicles you have, the higher your AMH level typically is. AMH naturally goes down as a person gets older until it reaches close to zero during perimenopause. While there is no international standard for what a normal AMH level is, some studies have tried to create models for what’s considered normal for specific ages. Check out this article to find out more about AMH levels at different ages.

Antral follicle count

Antral follicle count (AFC) is another number to be aware of before egg freezing. AFC is used in fertility assessments to estimate the number of developing follicles in someone’s ovaries at a specific point in the menstrual cycle using ultrasound. As mentioned before, the more follicles you have (the higher your AFC is), the higher your AMH level. And just like your AMH, your AFC will also naturally go down as you age. 

How these values affect your egg freezing success 

Unfortunately, there isn’t a lot that can be done about aging or about the decline in AMH and AFC that goes with it but there are a few things to know about how they affect your egg freezing changes. 

• Ovarian reserve assessment. Age, AMH and AFC all provide valuable information about a person’s ovarian reserve. In general, younger age, higher AMH levels, and a higher AFC are good indicators that you have a larger pool of potential eggs in the ovaries. This means that you’re more likely to produce more eggs during an egg retrieval cycle, which increases the chances of a successful egg freezing cycle.
• Response to ovarian stimulation. Part of the egg freezing cycle includes taking medications to stimulate the ovaries to develop multiple eggs at once (as opposed to just one during a natural, unmedicated menstrual cycle). The response to these medications can vary based on age, AMH, and AFC. People who are younger and those who have a higher AFC/AMH tend to have a better response and produce more mature eggs during the stimulation. This increases the chances of retrieving a larger number of high-quality eggs for freezing.
• Number of cycles. In some cases, people with a lower AFC and/or AMH may have to go through more than one egg freezing cycle in order to get an adequate number of eggs. This can get costly and time-consuming pretty quickly.
• Future fertility potential. The number and quality of frozen eggs affects the chances of having a successful pregnancy when the frozen eggs are later thawed, fertilized, and transferred during an in vitro fertilization (IVF) treatment. A higher AFC and AMH can mean a higher number of frozen eggs, which increases a person’s chances of success in the future. However, neither of these numbers is the end-all-be-all here. In fact, while AMH does seem to have some association with live birth rates after IVF, its ability to actually predict a live birth is not that great, especially for younger people.

Again, all three of these factors aren’t necessarily things you can change so it can be easy to get discouraged if your values aren’t where you want them to be. Remember that each of these is just one value your provider looks at to assess your overall reproductive potential. No value by itself can completely predict your chances of conceiving naturally or define your fertility. A comprehensive assessment of a person’s fertility potential has to be done by a fertility specialist before jumping to any conclusions and making decisions about fertility preservation.

During an egg freezing cycle

Now, let’s go through the factors during an egg freezing cycle that can affect your chances of success.

Quantity and quality of eggs retrieved

The success rates of egg freezing cycles are significantly influenced by both the number and quality of eggs retrieved. The number of eggs retrieved is important because it directly correlates with the chances of developing viable embryos after thawing. This is definitely a case of “more is more”--the more eggs that are successfully frozen, the higher the probability of having viable embryos when the time comes. 

However, the quality of the retrieved eggs is just as important. High-quality eggs have a better chance of surviving the freezing and thawing process than low-quality ones. So, as you can imagine, a cycle with lots of eggs that are all low-quality isn’t necessarily more successful than another cycle that produced less eggs but they’re all high-quality. 

As a result, fertility providers will always aim to maximize both the quantity and quality of the eggs retrieved. This is essential for improving  the success rates of egg freezing cycles so that, ultimately, we end up with healthier embryos and better chances of a successful pregnancy.

Type of freezing method used 

There are two main techniques used for freezing eggs: slow freezing and vitrification. The slow freezing method involves gradually lowering the temperature of the eggs, which allows ice crystals to form within the cells. This process can damage the delicate internal structure of the eggs, which can lead to lower viability and success rates once the eggs are thawed. In contrast, vitrification is a freezing process that solidifies the eggs quickly without forming ice crystals. This method protects the cell’s internal structures better and has been shown to increase post-thaw survival rates. This in turn, means higher success rates during IVF treatments. It makes complete sense, then, that vitrification has become the preferred way to freeze eggs.

Tips to increase egg freezing success rates

Alright, so now that we’ve established what’s important when it comes to egg freezing, what exactly can you do to maximize these factors for yourself? 

• Consider freezing your eggs at a younger age. There may not be much we can do about the fact that we’re all getting older but in terms of egg freezing, the general rule is that the younger you can do it, the better. According to the American Society for Reproductive Medicine (ASRM), the ideal time to freeze your eggs is in your 20s and early 30s, while you have more eggs and those eggs are healthier. So, whether you’re 25 or 35, your eggs today are still probably healthier than your eggs in one, five or 10 years!
• Optimize your fertility health before beginning the egg freezing process. This step will look a little different from person to person since everyone has their own unique medical history and concerns. Generally speaking though, optimizing your health will include following a balanced diet and making other healthy lifestyle choices. In some cases, you may want to consider adding certain vitamins and supplements to your regimen too. Make sure to talk to your fertility specialist if you’re not sure!
• Consider using a different type of freezing method. Ask your fertility provider which method they plan to use when freezing your eggs. Vitrification is the more common method now given its improved outcomes when compared to slow freezing but it doesn’t hurt to confirm that this is the method your particular clinic uses.   
• Consider doing multiple egg retrieval cycles. If you have the resources and time to do multiple cycles, this can vastly improve the pool of eggs to choose from in the future. This is an especially helpful option for people who are older or have a low AMH level or AFC. If your fertility provider thinks more cycles will improve your chances, they’ll discuss those recommendations with you.
• Be particular about the clinic you choose. There are a ton of fertility clinics to choose from nowadays, so take the time to do some detective work and find one that works for your needs. If you know people who’ve used a fertility clinic, ask them for their honest opinions. Read reviews. Look up the providers’ credentials (usually listed on the clinic’s website). You can also find out the clinic’s success rates in terms of live births and other important statistics through their website. Schedule a couple consultations to compare your options. Make sure to come with questions and to actually ask them all. If you’re not sure what to ask, check out some suggestions here. 

Emotional considerations

It’s important that we take a second to talk about the emotional side of this experience. For many people, the decision to freeze their eggs is tied to hopes of preserving future fertility. When a lab test or a cycle doesn't yield the desired results, there can be feelings of hopelessness, frustration, sadness, anxiety, and uncertainty about future family planning options. On top of that, this isn’t a cheap or simple process! So there can be disappointment stemming from both the financial and physical investments that have been made. 

Because of all of this, seeking support and guidance throughout this process has to be a priority. Support from both loved ones and through professional counseling can make a huge difference when it comes to coping with the emotions you might be dealing with. 

Establishing clear and open communication with your fertility providers also plays a key part in helping people cope with the challenges that might come up. Your providers know the ins and outs of your particular situation so they’re the most qualified to tell you what you need to prioritize (and what you can ignore) to improve the success of your egg freezing cycle(s).

With all the nuances involved here, it’s important not to get lost in the weeds. Fertility is impacted by so many factors that you can drive yourself crazy trying to manage all of them. Remember, you are more than any number. 

Conclusion

To recap, there are several different factors that can affect the success of an egg freezing cycle including your age, AMH level, AFC, the number and quality of eggs retrieved, and the type of freeing method used. Some of these, you don’t have control over. For the ones you can control, there are a few things you can do. 

Optimizing your fertility health before the egg freezing process, freezing your eggs at a younger age, doing more than one cycle, and using a safer freezing option are all ways that you can improve your chances of a successful freezing cycle. This process can be so overwhelming— focusing on the things that you can control can help you feel more grounded throughout your fertility journey. 

Freeze by Co is here to help you every step of the way on that journey. With our Keep program, you’re able to freeze your eggs and keep them all for yourself, on your timeline. In addition, you’ll have access to our online support community, the Nest. This is a valuable resource that lets you engage with other people freezing their eggs at the same time!

Missy Modell is no stranger to breaking boundaries. A fierce advocate for women's rights and an inspiring artist, she is open and honest about her own experiences. In a candid interview with us, Missy shares her journey of freezing her eggs, a deeply personal and empowering decision that reflects the challenges and choices women face today.

From doubt to decision

"I was really against egg freezing at first!" Missy shared. But her initial resistance gave way to reflection and realization. "Ultimately, I decided that at this very moment in my life and career, I am not ready to have children but I do know that I want them at some point."

The process: challenges and triumphs

Missy started the process at 35, but got scared and held off for a year. She finally began a year later, but observed significant changes in her body during that year, as her AMH dropped from 2.5 to 1.5, a realization that underscored the urgency of her decision. "I knew that if I was going to do it, now was the time!" she told us.

They ultimately retrieved 13 eggs and were able to freeze 10. Missy's reflections resonate with empowerment and gratitude. The rewards were not just in the outcomes but in the newfound connection with her body and a sense of autonomy and control over her future. Her journey is a testament to resilience, self-awareness, and the power of informed and thoughtful decision-making.

On the complexities of the egg freezing process, Missy shared, "The hardest part was honestly the aftermath. I had a sense of doom and depressed feelings that lasted a few weeks." 

But her journey wasn't without triumphs. "The thing that worried me most was being under anesthesia for the retrieval, but that ended up being one of the seamless parts of the whole experience! I felt so safe," she revealed.

Reflections and looking ahead

"I honestly can’t believe I did it! I am really proud of myself and very happy with my decision," Missy said, looking back on the experience. Her relationship with her body changed profoundly as well: "The entire journey made me feel so connected to my body, my cycle, and other women who have also undergone fertility treatment."

"The entire journey made me feel so connected to my body, my cycle, and other women who have also undergone fertility treatment."

This connection, born from a deeply personal experience, transcends the medical procedure itself. It's a testament to a shared understanding and empathy among women who have faced similar decisions. Missy's story isn't just about the choices she made for her future; it's a unifying narrative that resonates with countless women navigating their reproductive journeys, forging bonds of strength, compassion, and courage.

Advice for others

Missy's advice for others is rich in empathy and wisdom. "Freezing your eggs is not a failure. It took me so long to get past the shame of it all but I quickly learned that it’s an incredibly kind thing to do for yourself." She also stresses the importance of self-care, advising, "Be compassionate and kind to yourself. This is a very emotional process that brings up a LOT. Focus on the gratitude for being able to go through this process in the first place and how good you will feel when it’s done!"

Freezing your eggs is not a failure. It took me so long to get past the shame of it all but I quickly learned that it’s an incredibly kind thing to do for yourself.

Missy Modell's candid and heartfelt sharing paints a vivid picture of a journey filled with challenges, resilience, and empowerment. Her experience, in her own words, showcases a deeply personal aspect of women's health that often goes unspoken. Missy's story is more than just about egg freezing; it's a celebration of female strength, autonomy, and the embracing of life's possibilities. Her reflection rings loud and clear: "Women are truly fearless," and her own story stands as a testament to that truth.

Read more:

• How Many Eggs Should I Aim to Freeze?
• How Many Times Should I Freeze My Eggs?
• Should I Freeze My Eggs If I'm Not Yet Sure I Want Children?

Simmone Taitt, Founder and CEO of Poppyseed Health, is no stranger to reproductive health. In an interview with Cofertility, Simmone opens up about her embryo freezing experience. She shares her motivations, challenges, and the rewards she discovered along the way, providing invaluable insights for those considering this transformative path.

Eggs vs embryos

"I decided to create embryos with my partner because I was undergoing surgery for stage four endometriosis," Simmone explains. "There was a chance that I was going to lose one of my ovaries, and we wanted to preserve our options as much as possible while also addressing the endo." Unfortunately, she did lose her left ovary and fallopian tube, making the decision to create embryos even more significant.

Simmone froze her eggs at the age of 37, retrieving a total of 11 eggs. "I was 37 years old when I retrieved my eggs and we got 11 eggs," she shares. "The ovary that I ended up losing only produced 2 eggs while the other produced 9 eggs." Despite the challenges she faced, Simmone's determination remained unwavering.

Read more about choosing to freeze eggs vs embryos

Reflections on the process

Reflecting on the egg freezing process, Simmone shares, "The process was way more time consuming than I anticipated." She explains the rigorous routine of blood tests every other day for nearly two weeks and intravaginal sonograms during every visit. Simmone's experience was further complicated by the side effects of the stimulation medication due to her endometriosis. "It was tough on my body. I gained 10 pounds during the stimulation period and was very bloated," she reveals. However, the reward of creating embryos outweighed the difficulties she encountered.

For Simmone, the hardest part of the process came after the retrieval. "About four weeks after my first embryo transfer, I ended up in the hospital with a swollen arm," she recalls. "It turned out that I had a deep vein thrombosis (DVT)." This setback disrupted her plans for additional embryo transfers. Despite the challenges, Simmone's spirit remains unbroken.

Picking a fertility clinic

When it came to choosing a fertility clinic and medical professional, Simmone had specific criteria in mind. "I specifically wanted an REI who had experience with medically complex patients with inflammatory diseases," she explains. After consulting with various specialists, Simmone selected an REI whom she felt comfortable and safe with. Although her own journey has not resulted in a successful pregnancy (yet), she referred two friends to the same REI, both of whom had successful first transfers and babies. Simmone emphasizes that each person's body is different and outcomes aren't guaranteed.

Simmone acknowledges the impact of the egg freezing process on her personal and professional life. "Thankfully, I was able to go in for my monitoring hours first thing in the morning, which was the most convenient for my schedule," she shares. However, she also highlights the significant cost involved. "The cost is astronomical," she reveals. While her partner's company covered one round of egg retrievals, Simmone and her partner had to use their savings, around $5,000 to $6,000, to cover the expenses of medication and other aspects of the cycle.

The emotional and psychological aspects of egg freezing

Managing the emotional and psychological aspects of egg freezing presented its own challenges for Simmone. "I had a lot of friends who [have done IVF]. The process is similar, so I had a lot of knowledge going into it, but it was still emotionally tough for me," she admits. Simmone relied on her partner, family, and friends for support. The hormonal effects of the medications heightened her emotions and made her feel tender and vulnerable during that time.

Looking back on her egg freezing experience, Simmone reflects on the need for better awareness of the possible side effects. "I think we commercialize the egg freezing process and IVF to be 'easy' and 'accessible' and 'simple'," she states. Simmone wishes she had been more informed about the potential challenges involved and emphasizes the importance of a realistic understanding of the procedures.

Advice for others

Offering advice to those considering freezing their eggs, Simmone encourages open conversation and seeking support. "It's important to talk to people who have been through the process and get the real stories," she suggests. Simmone emphasizes the deeply personal nature of the decision and underscores the need for support, guidance, and empathy throughout the journey.

Simmone Taitt's story is one of resilience, hope, and empowerment. Her decision to freeze her eggs was driven by a desire to preserve her fertility amidst health challenges. Despite the obstacles she faced, Simmone's unwavering spirit and determination propelled her forward. Her experience serves as a reminder that while the road may be challenging, there is strength in preserving options and embracing the possibilities that lie ahead.

As women, we are often tasked with making complex decisions about our bodies, our health, and our future. Among the myriad of choices, one of the most significant is the decision of whether or not to freeze our eggs. But once you've made the decision and plan to go through the process, you now may be wondering, "What exactly happens to my eggs after I freeze them? Where do they go? How long can they remain frozen?"

Egg freezing, also called oocyte cryopreservation, offers a chance to focus on other stuff now while planning for your future family. But how does it work, and what happens to your precious eggs once they are safely frozen? Let's delve into this fascinating, sometimes bewildering world of fertility preservation.

The egg freezing process: a quick recap

Before we venture further, let's refresh our understanding of the egg freezing process. It starts with hormone injections that stimulate your ovaries to produce multiple eggs. These eggs are then retrieved through a minor surgical procedure, and once retrieved, they are immediately frozen in a state-of-the-art laboratory. Following the retrieval and freezing process, your eggs are stored in a secure and carefully monitored cryo-storage facility. 

Egg freezing and preservation

Vitrification is a newer and more effective method of freezing eggs that has largely replaced older methods such as slow freezing. With vitrification, eggs are quickly frozen using a high concentration of cryoprotectants and then plunged into liquid nitrogen for storage. This process creates a glass-like state that preserves the eggs in a nearly perfect condition. In fact, vitrification ensures a very high rate of survival of the eggs, typically 95% or above.

Compared to slow freezing, which can damage the eggs and reduce their viability, vitrification has a higher success rate of producing healthy embryos for later use. It has become the preferred method of egg freezing for most fertility clinics and has allowed more patients to successfully preserve their fertility.

If you have any doubts about your clinic, you can ask them what type of method they use for egg freezing. It's important to do your research and choose a reputable fertility clinic with experience in vitrification if you're considering egg freezing.

Long-term storage and monitoring

Once the eggs are frozen, they are stored in liquid nitrogen. Some clinics keep those frozen eggs stored at an onsite lab, but in most cases they are shipped to an offsite facility. As soon as you’re ready to use them, they can be safely shipped back. 

In either case, the frozen eggs' care doesn't end at storage. They are monitored regularly to ensure the liquid nitrogen levels remain constant, and the facility's temperature control and security systems are working correctly. A well-maintained facility prioritizes meticulous record-keeping, tracking the storage duration and any other pertinent details about each egg. 

Cofertility members can take advantage of our partnership with TMRW Life Sciences, a fertility technology company that has developed the world's first automated solution for storing and managing frozen eggs and embryos. 

TMRW's technology platform digitally identifies, tracks, monitors and stores patients' frozen eggs and embryos with safety, accuracy, efficiency and transparency. TMRW's platform sets a new standard of care by reducing potential points of failure by 94% compared with manual systems.

So what is TMRW doing differently? 

• Digital labeling - instead of handwritten labels, TMRW uses digital labeling and RFID tracking. With this tracking system, clinics always know exactly where your eggs and embryos are and can easily find them when you’re ready to use them.
• Automated management - instead of relying on manual processes, TMRW has a new fully-automated digital system that helps eliminate 94% of potential failure points
• Real-time inventory - TMRW has gone the extra mile by creating a 24/7 cloud-based monitoring system with real-time inventory updates to provide new levels of safety, transparency, and peace of mind. 
• Active monitoring - TMRW provides 24/7 digital monitoring (thousands of daily checks!) and expert human oversight to identify potential issues before they become a problem.

Will my eggs survive the thaw?

Several factors can impact the success of egg thawing, including your age when the eggs are frozen, the number and quality of the eggs, the technique used to freeze the eggs, and the quality of the clinic’s laboratory. 

The quality of the eggs is also a crucial factor in egg thawing. Good quality eggs have a higher chance of survival and fertilization. However, even with good quality eggs, there is no guarantee of success, and the process may need to be repeated to achieve pregnancy.

If and when you decide to use them

When you decide the time is right to use your frozen eggs, they are thawed in the lab using a warming solution. 

But keep in mind that thawing is just the first part. The eggs will then need to be fertilized with sperm and grown into embryos. The surviving eggs are then fertilized using a process called intracytoplasmic sperm injection (ICSI), where a single sperm is injected directly into each egg.

After fertilization, the resulting embryos are monitored for a few days as they begin to develop. The most viable embryos are then transferred to your uterus in a procedure similar to a pap smear. If successful, the embryo implants in your uterus and grows, leading to pregnancy.

Generally, the younger you are when freezing your eggs, the better the chances of success. Eggs frozen in your late 20s or early 30s have a higher chance of survival and successful fertilization compared to those frozen in your late 30s or 40s.

If you decide NOT to use them

What if, down the line, you decide not to use your eggs, or you have more than you need? 

One study of egg freezing patients at UCSF found that 89% believed they would be glad they froze their eggs, even if they never used them to conceive a child. So if you don't end up needing your frozen eggs down the line, there are a few options for what to do with them.

• Keep them in storage. Most storage facilities offer long-term storage options (our partnership with TMRW includes plans up to 10-years long), allowing you to keep your eggs frozen for as many years as  necessary. This may be a good option if you're not yet ready to use the eggs but want to keep them as a backup plan.
• Donate the eggs to someone else who may need them. Egg donation is a process of donating eggs to another person or couple who needs them, such as LGBTQ+ families or those suffering from infertility. This can be a wonderful gift for those who may not be able to have a child otherwise. If you go through our Split program, you will have already been cleared as a donor and can easily donate these additional eggs. If you’re not part of the Split program but think you may be interested in this down the line, talk to your doctor as they may be able to do some additional donor-related screening during your egg freezing process. 
• Dispose of them.  If you decide that you no longer need your frozen eggs and don't want to continue storing them or donate them, simply request that they are disposed of by the clinic or storage facility.
• Donate to science. Many research studies rely on donated eggs to investigate new techniques and treatments for infertility. Ask your clinic if this is an option.

Emotional considerations

Aside from the practical aspects, it's important to acknowledge the emotional journey involved in egg freezing. It's normal to feel a mix of emotions – relief, hope, anxiety, or even sadness. Know that these feelings are common and valid. Don't hesitate to seek support, be it from a trusted friend, family member, a professional counselor, or the Cofertility community.

Summing it up

The journey of your eggs from freezing to potential future use is complex and exciting, underscored by sophisticated science and meticulous care. Deciding to freeze your eggs can be an empowering choice, giving you autonomy over your fertility and future family planning. Knowing what happens to your eggs after freezing them can provide comfort and clarity as you navigate your fertility journey.

In the end, egg freezing is an investment in your future, offering an opportunity to expand your family when the time is right for you. It's a testament to the advancements in reproductive science and a tool for you to take control of your fertility. Trust in the process, seek support when needed, and above all, know that your choices are valid, and your feelings are heard. After all, the journey to parenthood, in whatever form it takes, is a voyage of hope, love, and extraordinary potential.

If you’re ready to freeze your eggs, we’re here to help. Reach out or learn more about our Freeze program.

Read more:

• Egg Freezing: How Long Can My Eggs Be Stored?
• Egg Freezing Thaw Rates
• When Should I Freeze My Eggs?

As if choosing to freeze or donate your eggs isn’t a big enough decision — now it’s time to choose who you’re going to work with to do it. With a seemingly endless number of fertility clinics, agencies, and egg banks to choose from (some with more questionable marketing tactics than others), we know how daunting this decision can feel. We’re firm believers in the power of community and know that the best way to make a decision as big as this one is to hear firsthand from other people who have gone through the process themselves. We asked some of our Split members and intended parents about why they chose Cofertility and their experiences so far. Keep reading to see what they had to say.

Why Cofertility?

"Physicians are often forced to sacrifice their most fertile years for their training, and that becomes such a huge source of anxiety for so many female doctors.

This is an opportunity to preserve some of your fertility while doing something amazing for another family." - Christina, Split member

“Something that has held me back from starting a family is financial limitations. However, if I could give someone the opportunity while I pursue my career in hopes of becoming financially unlimited, that would be amazing. ” - Nancy, Split member

"As a fourth year med student, I'm at a stage in my life where having a family isn't really an option and it won't be for 5-10 years. This idea is just beautiful. I can't believe we didn't figure something like this out sooner." - Emily, Split member

“I am incredibly independent and feel that I want to best prepare myself to have options in the future if I have a child on my own or with a partner, that I can ensure a safe and healthy pregnancy in my future when I choose to do so. Entering my late 20s, I have seen more and more of my friends struggle with fertility issues and how incredibly difficult that process is. As a long time nanny, there's nothing more that makes me happy than knowing how love a child can be, so why not be part of that journey!” Claire, Split member

Hear from some of our matched Split members

“Once I met the prospective parents, it was clear they selected me more for my personality than any physical attributes. Overall, I’ve felt like I’m valued as a complete person, not just for my eggs—and they’re so happy to help me on my fertility journey as well.” - Kristen, Split member.”

“[It was important to me to match with a couple] where at least one person was African American. I was also drawn to helping another queer couple in this process. Fortunately, there’s a lot of autonomy and flexibility in terms of what this [journey] looks like for each person.” - Arianna, Split member

Hear from Intended Parents

“We feel so lucky to have come across Cofertility as we’re making the most important decision of our life. They’ve taken what’s become a depersonalized journey and made it into something deeply emotional. They take the time to get to know Intended Parents and Split Members to make sure it’s a perfectly aligned match all around." - Mark & Chirag, Cofertility intended parents

Start your egg freezing journey with Cofertility

Working with Cofertility means working with a platform that honors donors, intended parents, and donor-conceived people alike. We’re here to make your egg freezing journey the human-centered, accessible, and just plain better experience that you deserve with our two unique programs.

With our Split program, members who qualify based on clinic criteria can freeze their eggs entirely for free when they donate half to a family that can’t otherwise conceive.

Through our Keep program, members self-fund their egg freezing journey and keep the entire egg yield for themselves, with discounts and support from our team every step of the way.

With both programs, members also get exclusive access to our members-only community, where they can connect with others going through the egg freezing and donation processes at the same time and lean on each other for support and encouragement.

To see which programs you qualify for and start your journey today, click the link below to take our free, two-minute quiz.

Cancer is a challenging journey that often necessitates numerous life-altering decisions. For women of reproductive age, one of these critical decisions is understanding how cancer treatments might impact fertility and what can be done to preserve it. In this article we’ll explore this delicate intersection of oncology and reproductive health, and talk about the option of egg freezing.

The impact of cancer treatments on fertility

Cancer treatments, while lifesaving, can significantly affect fertility. These impacts can vary depending on the specific treatment, the dose, your age, and the area being treated.

• Chemotherapy medications, designed to target rapidly dividing cells, may inadvertently impact the eggs in the ovaries. This decrease can result in infertility, primary ovarian insufficiency, or a narrowed window of fertility, much like natural aging. Women over 35, having fewer eggs to start with, are more susceptible to this effect.
• Radiation therapy targeted at the pelvis or the entire abdomen can harm eggs and the uterus. The radiation can lead to scarring, or fibrosis, in the uterus, making it challenging for the uterus to accommodate a growing fetus. Consequently, women may face difficulties in conceiving or carrying a pregnancy to term, increasing the risk of miscarriage or premature labor.
• Treatments involving the brain, such as surgery or radiation, can affect the pituitary gland responsible for releasing hormones that stimulate egg maturation and ovulation. While the eggs in the ovaries are not directly damaged, the disruption in hormone regulation can affect fertility. However, hormone replacement medications may help restore fertility in these cases.
• Surgery involving one or both ovaries or the uterus can directly impact fertility. The degree of this impact would depend on the extent of surgical intervention.

If you are considering cancer treatment and are concerned about its potential impact on your fertility, it is important to discuss your concerns with your oncologist and/or a fertility doctor. They can provide you with information about the potential effects of cancer treatment on fertility and help you understand your options for preserving your fertility before treatment begins.

Egg freezing options

For those about to embark on cancer treatment, a few fertility preservation options can increase the chances of having biological children in the future. 

Egg freezing (oocyte cryopreservation) is a process involving stimulating the ovaries with hormones to produce multiple eggs, which are then retrieved and frozen for future use. The entire process takes about two weeks from start to finish, but the start date depends on your menstrual cycle. 

If you have a partner or choose to use donor sperm, the eggs can be fertilized before freezing, creating embryos for future implantation. The benefit of fertilizing the eggs immediately is that you will know how many embryos you have for future use.

Ovarian tissue freezing is a relatively new and experimental technique that involves surgically removing and freezing ovarian tissue, which contains thousands of immature eggs. This tissue can later be re-implanted to restore fertility or used to mature eggs in the laboratory. This may be an option for those who are not able to undergo egg freezing due the urgent need to begin cancer treatment.

To freeze or not to freeze

Making a choice on which fertility preservation option to pursue, if any, can be a difficult decision. A myriad of factors play into this decision, including your current health, age, cancer type, the proposed treatment regimen, personal circumstances, and future family plans.

Navigating a cancer diagnosis while also thinking about future fertility can be emotionally overwhelming. There are not only physical implications to consider, but also emotional, psychological, and social dimensions to this journey.

The chosen method must be compatible with your treatment plan and timing, as some methods require hormonal stimulation and time to mature and retrieve the eggs. A fertility doctor, alongside your oncology team, can provide the most accurate advice based on your unique situation.

It's important to seek emotional and mental health support during this challenging time. Reach out to your health care team, a mental health professional, supportive loved ones, or a support group of others going through a similar experience. It can be helpful to share your feelings, fears, and hopes, and to hear others' experiences and insights.

Financial considerations - how to pay for egg freezing 

Another important aspect to consider is the cost of fertility preservation treatments. These procedures can be expensive, and not all are covered by insurance. Average egg freezing costs range from $10,000 - $20,000 for consultations, testing, ultrasounds, medications, and the egg retrieval, plus the ongoing cost of annual storage. But ultimately depends on the clinic you’re going to, where you are located, the medications you are prescribed (it differs based on your age and body), and where/how long you store the eggs.

There may be ways to lessen the financial burden, including:

Insurance coverage 

Begin by thoroughly understanding your insurance coverage. Some health insurance plans provide partial or complete coverage for fertility preservation, especially in cases of medically necessary treatments such as cancer. Legislation in certain states mandates insurance coverage for fertility preservation for cancer patients. 

As of the writing of this article, these states require health insurance plans to cover medically necessary fertility preservation:

• California
• Colorado
• Connecticut
• Delaware
• Illinois
• Kentucky
• Louisiana
• Maryland
• New Hampshire
• New Jersey
• New York
• Rhode Island
• Texas
• Utah

Reach out to your insurance provider to understand what is covered and what out-of-pocket costs you can anticipate.

Flexible Spending Account (FSA) or Health Savings Account (HSA)

If you have an FSA or HSA through your insurance plan, these funds can often be used to cover fertility preservation expenses. Check with your plan administrator to confirm what expenses qualify.

Tax deductions

The IRS has traditionally considered fertility preservation treatments, like egg freezing, to be tax-deductible when they are deemed medically necessary. This typically refers to situations where a medical condition or treatment (such as chemotherapy for cancer) could cause infertility. You’ll want to talk to a tax professional about which egg freezing expenses you can deduct from your taxes.

Negotiating prices and shop around 

Don't hesitate to discuss the costs with your fertility clinic. Some clinics may offer discounted rates or payment plans for individuals facing financial constraints. Get pricing from a few clinics to see your options. 

Financing options

There are a growing number of financing options, such as loans or payment plans, to help patients pay for egg freezing. These options allow you to spread the cost of the procedure over several months, making it more manageable. For example, Sunfish makes egg freezing (and fertility treatment in general) attainable for all types of families with low-interest loans or lines of credit.

Financial assistance programs and grants for cancer patients

Numerous organizations offer grants or financial aid to cancer patients seeking fertility preservation. Examples include the Livestrong Fertility Program, Team Maggie, Chick Mission, the SAMFund, The Ferring Heartbeat program, and Fertile Action. These organizations aim to alleviate the financial burden of fertility preservation and increase access to these vital services.

Crowdfunding

With the rising popularity of crowdfunding platforms, many people turn to their community, near and far, for financial support. Websites like GoFundMe can be used to raise funds for medical treatments.

Employer benefits 

Increasingly, employers are recognizing the importance of supporting their employees' reproductive health and are incorporating fertility benefits into their packages. Explore whether your employer offers any such benefits or whether they would consider adding them.

Options if you choose not to freeze your eggs

If you don’t freeze your eggs before cancer treatment, it's important to remember that does not mean the end of the road for parenthood. There are multiple paths available to build a family. 

It may be possible to regain fertility naturally after cancer treatments, particularly if you are under 30 at the time of treatment. You’ll want to talk with your oncologist and a fertility doctor about when it would be safe to try for a pregnancy and the potential risks involved.

For women whose ovarian reserve has been significantly impacted, the use of donor eggs can be a great option. In this process, eggs from a donor are fertilized with your partner's sperm (or donor sperm), and the resulting embryos are implanted in your uterus. This path allows you to experience pregnancy and childbirth.

If the uterus has been damaged by radiation or surgery, or if pregnancy poses a health risk, gestational surrogacy might be an option. In this case, an embryo (created with your egg or a donor egg and your partner's or a donor's sperm) is carried by a gestational carrier.

Finally, adoption remains a heartfelt path to parenthood for many individuals and couples. Adopting a child can be a fulfilling choice that meets the deep desire to raise and nurture a child.

Living with the aftermath of a cancer diagnosis can be challenging, particularly when it affects your family planning. However, remember that numerous avenues to parenthood remain open, and while they may not be the paths you initially envisioned, they can be equally rewarding and enriching. Your dream of becoming a parent can still be a reality; it might just involve a different route than you originally planned.

Summing it up

Navigating the landscape of cancer and fertility can be laden with emotional and medical complexities. However, armed with knowledge about potential impacts and available options, you can make an informed decision that aligns with your future family-building aspirations. Your oncology and fertility teams can provide guidance and support, helping you weave your way through this intricate journey and minimizing future regrets. In the end, the goal is to optimize not just survival, but also quality of life and future dreams.

Embarking on the path of family planning is an exciting journey filled with hope and, often, uncertainty. One area that typically gives rise to a multitude of questions revolves around oocyte cryopreservation, commonly known as egg freezing. While this medical breakthrough has provided countless women with greater reproductive autonomy, it's still not a definitive guarantee of biological motherhood.

In this guide, we’ll try and answer one of the most common questions around egg freezing: the chances of live birth. 

From frozen eggs to baby

At every stage of the in vitro fertilization (IVF) process (which is technically what egg freezing is, plus embryo fertilization in a lab), there's a certain level of attrition. Some collected eggs may be immature, making them unsuitable for freezing. Others may not withstand the thawing process. When you’re ready to fertilize those eggs into embryos, they will not necessarily all fertilize, and some fertilized embryos may fail to mature into viable embryos suitable for transfer. Even embryos that reach the transfer stage might not be genetically normal. And those that are genetically normal may not result in a viable pregnancy or live birth.

As a result, egg freezing is better viewed as a way to increase your chances of pregnancy down the line, rather than an insurance policy or a surefire plan. It’s a path filled with potential, and definitely gives you greater optionality when you’re ready to  have kids, but — and we are always very transparent about this — there is unfortunately no absolute promise of a live birth at the end of the egg freezing process.

How many eggs should I freeze?

Given these complexities, a pressing question for many women is, “how many eggs should I freeze to increase my chances of having a baby?” The answer is nuanced and largely depends on two variables: the age at which the eggs are frozen, and how many children you want.

Unfortunately, the quality of eggs can't be assessed before fertilization is attempted, adding another layer of uncertainty to this equation. Still, we can provide an approximate guide based on averages, which can inform individualized counseling, treatment planning, and expectation management.

One study out of Harvard Medical School of 520 cycles found the chances of live birth varies based on age and number of eggs frozen (see chart below). This guidance is not precise, but offers an approximate benchmark to guide you through your fertility journey. 

How many eggs will I get?

Another common inquiry from patients is how many eggs are likely to be retrieved and preserved in a single egg freezing cycle. The good news is that this is fairly easy for fertility doctors to predict using two crucial measures: anti-Müllerian hormone (AMH) and antral follicle count (AFC).

AMH and AFC, both estimators of ovarian reserve, can provide an approximation of the number of eggs that can be retrieved from a stimulated cycle. For instance, an AMH level of 15 pmol/L (2.1 ng/mL) could predict a yield of approximately 12 to 18 eggs. Similarly, AFC's numerical value directly correlates with the number of eggs potentially collected in one cycle, with a rough ratio of 1:1. So if your fertility doctor counts 15 antral follicles during the transvaginal ultrasound, you could potentially retrieve 15 eggs in a single cycle (note this number could be lower or higher based on other factors).

Will I have enough eggs to share?

Cofertility’s Split program offers women a chance to freeze their eggs *for free* when donating half of the eggs retrieved to a family who cannot otherwise conceive. If you qualify for the program and decide to donate half of your retrieved eggs, every expense associated with the egg freezing procedure —  medications, supplements, travel if necessary, insurance, and 10 years of storage — are completely free of charge.

Since the number of eggs is predictable with AMH and AFC, we’re only able to accept people into the program if we are confident they would have enough eggs to “split”. 

Setting expectations 

You can look at the probabilities and hormonal indicators, but everyone’s egg freezing journey is unique. Age, health, lifestyle, and genetic factors can all play a role in your path to motherhood. Remember, egg freezing is a science, but it's not an exact one. The uncertainties are part of the process. And while the prospect of attrition can seem daunting, it's important to remember that every step forward is a step closer to the potential for success.

Navigating these complexities can feel overwhelming, which is why support and guidance are crucial. At Cofertility, our mission is to guide you through this journey, providing you with the necessary information, support, and encouragement to make the best decisions for your fertility future.

Although egg freezing can't offer guaranteed outcomes, it has undoubtedly provided hundreds of thousands of women worldwide with expanded options and increased flexibility in their reproductive timelines. By understanding the process's intricacies and setting realistic expectations, we can navigate this journey together, with optimism, resilience, and hope.

Freeze your eggs with Cofertility

Cofertility is a human-first, tech-enabled fertility ecosystem that provides people agency over if, how, and when they have babies — today or someday. We have two programs for egg freezers:

Our Split program offers women a chance to freeze their eggs for free when donating half of the eggs retrieved to a family who cannot otherwise conceive. If you qualify for the program and decide to donate half of your retrieved eggs, every expense associated with the egg freezing procedure —  medications, supplements, travel if necessary, insurance, and 10 years of storage — are completely free of charge. We don’t even need a payment or credit card up front, as the family you match with covers all the expenses.

Our self-pay Keep program allows women to freeze their eggs and keep them all for their future use. Through Keep, we offer our members partnerships and discounts to lighten the financial load of egg freezing, as well as access to our member community.

The benefits for of working with Cofertility include:

• Power of choice: Freeze your eggs more affordably or, if you qualify, freeze for free when you give half to a family who can’t otherwise conceive.
• Community: Our inclusive online spaces allow you to connect with others going through the process in our private online community.
• Compassion: We’ll always treat you with care, and our Split program gives you the opportunity to make someone’s family building dreams a reality.
• Data-driven: We provide you with trustworthy guidance and evidence-based research so you can make informed decisions about your fertility.
• Free egg freezing: Freeze and store your eggs for 10 years, entirely for free if you qualify for our Split program.

Ready to learn about more affordable (even free!) egg freezing with Cofertility? Fill out this quick quiz to learn about our accessible egg freezing options and see if you qualify for our programs — it only takes one minute.

Read more:

• Should I Freeze Eggs or Embryos?
• Which Matters More for Fertility: AMH or Age?
• Do’s and Don’ts During Egg Freezing: Alcohol, Baths, Exercise, and More