egg storage

Your fertility journey can be both exhilarating and complex and you may be looking for guidance on navigating the process of transporting your frozen eggs or embryos to a storage facility. We get it, and we're here to help.

Here are some important things you need to know about safely shipping your frozen eggs and embryos and what to consider as you weigh your storage options.

First things first—what is an offsite storage facility or  “biorepository”?

A biorepository is a facility that catalogs, stores, and maintains biological specimens – in this case, your eggs and embryos. The purpose of a biorepository is to store and preserve these specimens at extremely low (cryogenic) temperatures. Following a retrieval, you may choose to transport their specimens to a long-term storage facility, particularly if you plan to have them in storage for several years. 

What is the process for shipping frozen eggs and embryos to a biorepository? 

The shipping of frozen eggs and embryos involves the following steps:

1. Decide and indicate storage facility: Choose a long-term storage facility and inform both the clinic and the storage provider of your decision.
2. Clinic coordination and preparation: Notify your clinic that you want to move your specimens and find out what is required by the clinic to make this happen. Typically this includes: paying any outstanding balances, signing medical releases and consents, formally deciding where to ship specimens, and providing a point of contact information. 
3. Choose a courier: There are several shipping providers that specialize in shipping frozen eggs/embryos. Your clinic and/or storage provider may have recommendations or preferred specialized couriers.  
4. Specimens ship: Specimens begin the journey to your indicated storage facility and remain frozen in transit. 
5. Specimen storage confirmation: Receive confirmation from your storage provider that your specimens are safely stored.
   

What should I consider when deciding where to ship and store my specimens? 

Traditional cryostorage systems rely heavily on manual and analog processes. Cofertility has partnered with TMRW Life Sciences to provide our members access to one of the highest standards of care in offsite storage for frozen eggs and embryos in the US. TMRW is modernizing the management and storage of frozen eggs and embryos with cutting-edge technology that helps reduce the risk of specimen mix-up and loss.

Here are a few questions you can ask storage providers when evaluating different storage options:

1. Do you use digital labels and RFID tags to track and identify my frozen eggs/embryos? (Hint: not just handwritten labels)
2. Do you keep specimen storage data in a digital database, with a recorded audit trail of transactions? (Hint: not notecards, binders or Excel datasheets)
3. Do you use proactive monitoring -- thousands of digital daily checks + remote and in-person human monitoring? (Hint: not relying solely on reactive alarms that go off after there is a problem)
4. Do you help facilitate shipping and coordination with my clinic? (Hint: not having patients complete complicated documents without any guidance)

Is it safe to transport my eggs/embryos? Will my eggs or embryos be thawed in the process?

The process of shipping frozen specimens is safe and commonplace in the fertility space. With proper quality controls in place, specimens remain frozen throughout the duration of the shipment process. They are shipped in specialized cryogenic containers designed to maintain optimal cryogenic temperatures during shipping. 

If you choose to store your specimens with TMRW, as added security, both TMRW and its trusted shipping partners require the use of active, continuous temperature and GPS telemetry to monitor specimens during transit. Once specimens arrive at the TMRW Biorepository, all specimen handling is carried out by experienced embryologists who adhere to the highest standards in the US with strict quality control policies.

What are the key components of safely shipping frozen eggs and embryos?

The safe shipping of frozen eggs and embryos involves the following best practices,  which you should look for in a shipping provider:

1. Accurate documentation and labeling: Proper specimen documentation and package labeling is crucial to correct handling and tracking. 
2. Specialized shipping containers: Cryopreserved specimens are transported in a special shipping container called a vapor shipper - ideally suited for the transportation of frozen specimens. Liquid Nitrogen is added and retained in an absorbent material and the cold nitrogen vapor is released to maintain the specimen temperature below -150°C during transport.
3. Secure shipping process: A specialized medical courier service is scheduled to transport the vapor shipper, including monitoring temperature and location in real time.
4. Safe intake and verification: The receiving facility checks the container's integrity and verifies temperature before confirming specimen inventory and transferring the eggs or embryos to their final storage destination inside a specialized storage tank.

If you choose to transport your specimens to TMRW, our care team guides you through every step of the shipping process, helping you coordinate with your fertility center and/or through a trusted third-party shipping provider. TMRW has local delivery options and partners with specialized medical couriers for shipping.

What does it cost to transport my frozen eggs or embryos? 

The cost to transport your specimens is typically based on mileage, weight, and the quantity of eggs or embryos within the shipping container. This cost can vary widely depending on the courier company of your choice, typically ranging from about $600-$1200.  For all Cofertility members who choose to store specimens with TMRW, shipping to TMRW is included in the storage fee. 

Does insurance cover specimen shipping and/or storage costs?

Typically, specimen shipping services and specimen storage fees are out-of-pocket expenses. However, some insurance providers are beginning to include specimen shipping and/or storage in their coverage. It's important to check with your insurance provider to see if these services are covered and/or eligible for reimbursement.

After my eggs and/or embryos are stored in long-term storage, what do I need to do to move them to the clinic of my choosing when I’m ready to use them for treatment?

When you decide to send your frozen eggs or embryos back to a fertility clinic for treatment, you will contact your long-term storage facility to initiate the transfer process. For Cofertility members storing specimens with TMRW, TMRW’s team will collaborate with the fertility clinic of your choice to coordinate the shipment, preparation, transfer, and tracking of the requested specimens.

For more information on TMRW Life Sciences, visit their website at https://tmrwlifesciences.com. For more information about the TMRW Biorepository, please visit their Frequently Asked Questions or complete an inquiry here.  

If you are a Cofertility member ready to transfer your frozen eggs or embryos to TMRW, you can begin the storage intake process here - don’t forget to use your preferred partnership discount code! 

The ability to freeze human eggs has been a major breakthrough in reproductive technology. It has provided egg freezers with the option to delay childbearing, preserve their fertility in the face of medical conditions or treatments, and allow them to focus on their careers or personal goals without feeling the pressure of the "biological clock." However, many people wonder how long they can actually keep their frozen eggs in storage. In this article, we'll explore this question in more detail.

First off, what even is egg freezing?

Egg freezing, also known as oocyte cryopreservation, is a process where a patient’s eggs are extracted from the ovaries, frozen, and stored for later use. This procedure is typically done for those who want to preserve their fertility but are not yet ready to have children. It may also be recommended for patients who are facing medical treatments that could affect their fertility, such as chemotherapy.

The process of egg freezing typically involves hormone treatments to stimulate the ovaries to produce multiple eggs in one cycle. Once the eggs are mature, they are retrieved using a needle that is inserted through the vaginal wall under ultrasound guidance. The eggs are then frozen and stored in a special solution until they are ready to be used.

When you’re ready to use the frozen eggs, they are thawed and fertilized with sperm in a laboratory using a technique called ICSI (intracytoplasmic sperm injection). The resulting embryos are then implanted into the uterus (either yours, your partner’s, or the uterus of a gestational carrier) in the hopes of achieving a successful pregnancy.

What is vitrification?

Vitrification is a newer and more effective method of freezing eggs that has largely replaced older methods such as slow freezing. With vitrification, eggs are quickly frozen using a high concentration of cryoprotectants and then plunged into liquid nitrogen for storage. This process creates a glass-like state that preserves the eggs in a nearly perfect condition. In fact, vitrification ensures a very high rate of survival of the eggs, typically 95% or above.

Compared to slow freezing, which can damage the eggs and reduce their viability, vitrification has a higher success rate of producing healthy embryos for later use. It has become the preferred method of egg freezing for most fertility clinics and has allowed more patients to successfully preserve their fertility.

If you have any doubts about your clinic, you can ask them what type of method they use for egg freezing. It's important to do your research and choose a reputable fertility clinic with experience in vitrification if you're considering egg freezing.

So, how long can I keep my eggs in storage?

The length of time that frozen human eggs can be stored depends on several factors, including the quality of the eggs, the storage method used, and the regulations of the country or state where the eggs are being stored.

Scientifically, if you work with a good clinic in the United States using vitrification, you can keep them stored indefinitely. However, some countries, such as the United Kingdom have a cap on the number of years you can store eggs (for the UK, it’s now 55 years). Currently there is no limit in the United States.

Typically, I see patients that store their eggs for two to five years. With newer freezing methods, such as vitrification (described above), the chances of damage during storage are usually quite low.

How much will it cost to store my eggs?

The cost of storing frozen eggs varies based on the location of the storage facility, the amount of time you pay for (you can often get discounts for paying for more years upfront), and the transportation fees between the storage facility and your clinic. Egg storage is usually an out-of-pocket expense, ranging from $500 to $1,500 per year.

If you become a Split member at Cofertility, you can freeze your eggs for free when you donate half of the eggs retrieved to a family that can’t otherwise conceive. In this program, the cost of egg storage is completely covered for up to 10 years.

When should I plan on freezing my eggs?

The ideal time to freeze your eggs depends on a lot of things… including your age now, your overall health, and your personal goals.

Generally, I advise patients to consider freezing their eggs before the age of 35. This is because fertility declines as you get older, as the quality and quantity of eggs decrease. By freezing your eggs at a younger age, you may be able to preserve a greater number of healthy eggs for future use. It’s a bigger bang for your buck. 

However, every situation is unique, and there may be individual factors that influence your decision to freeze eggs at an earlier or later age. For example, if you have a medical condition or are undergoing a treatment that may affect your fertility, your doctor may recommend freezing your eggs earlier than age 35.

It's also important to consider your personal goals and timeline for starting a family. If you're not yet ready to have children but know that you want to in the future, freezing your eggs at an earlier age may give you more flexibility and options down the road.

Read more in When Should I Freeze My Eggs?

What happens if I don’t need the eggs down the line?

One study of egg freezing patients at UCSF found that 89% believed they would be glad they froze their eggs, even if they never used them to conceive a child. If you don't end up needing your frozen eggs down the line, there are a few options for what to do with them.

• Keep them in storage. Most storage facilities offer long-term storage options, allowing you to keep your eggs frozen for many years if necessary. This may be a good option if you're not yet ready to use the eggs but want to keep them as a backup plan.
• Donate the eggs to someone else who may need them. Egg donation is a process of donating eggs to another person or couple who needs them, such as LGBTQ+ families or those suffering from infertility. This can be a wonderful gift for those who may not be able to have a child otherwise.
• Dispose of them.  If you decide that you no longer need your frozen eggs and don't want to continue storing them or donate them, simply request that they are disposed of by the clinic or storage facility.
• Donate to science. Many research studies rely on donated eggs to investigate new techniques and treatments for infertility. Ask your clinic if this is an option.

What happens to my frozen eggs if I die?

This is something you will determine with the clinic before your egg retrieval procedure as part of your egg freezing agreement. If you have frozen eggs and pass away, the fate of your eggs will depend on this agreement. The options are generally that they are designated a beneficiary (such as your partner if you are married at the time), or discarded. 

If for some reason you didn’t state your preference up front, your eggs will likely become part of your estate and subject to the same rules and regulations as other assets you may leave behind. 

Summing it up

Newer egg freezing technology allows human eggs to be frozen indefinitely, although some countries like the UK have a limit of 55 years. Vitrification preserves the eggs in a nearly perfect condition, with a very high rate of survival of 95% or above.

While you can technically store eggs for your entire lifetime, it may get expensive. At some point, you may decide that you don’t want to use those eggs for yourself and instead donate them to another family, donate them to science, or have them discarded. Ultimately, the decision of how long to store your frozen eggs should be based on your personal goals and circumstances.

As women, we are often tasked with making complex decisions about our bodies, our health, and our future. Among the myriad of choices, one of the most significant is the decision of whether or not to freeze our eggs. But once you've made the decision and plan to go through the process, you now may be wondering, "What exactly happens to my eggs after I freeze them? Where do they go? How long can they remain frozen?"

Egg freezing, also called oocyte cryopreservation, offers a chance to focus on other stuff now while planning for your future family. But how does it work, and what happens to your precious eggs once they are safely frozen? Let's delve into this fascinating, sometimes bewildering world of fertility preservation.

The egg freezing process: a quick recap

Before we venture further, let's refresh our understanding of the egg freezing process. It starts with hormone injections that stimulate your ovaries to produce multiple eggs. These eggs are then retrieved through a minor surgical procedure, and once retrieved, they are immediately frozen in a state-of-the-art laboratory. Following the retrieval and freezing process, your eggs are stored in a secure and carefully monitored cryo-storage facility. 

Egg freezing and preservation

Vitrification is a newer and more effective method of freezing eggs that has largely replaced older methods such as slow freezing. With vitrification, eggs are quickly frozen using a high concentration of cryoprotectants and then plunged into liquid nitrogen for storage. This process creates a glass-like state that preserves the eggs in a nearly perfect condition. In fact, vitrification ensures a very high rate of survival of the eggs, typically 95% or above.

Compared to slow freezing, which can damage the eggs and reduce their viability, vitrification has a higher success rate of producing healthy embryos for later use. It has become the preferred method of egg freezing for most fertility clinics and has allowed more patients to successfully preserve their fertility.

If you have any doubts about your clinic, you can ask them what type of method they use for egg freezing. It's important to do your research and choose a reputable fertility clinic with experience in vitrification if you're considering egg freezing.

Long-term storage and monitoring

Once the eggs are frozen, they are stored in liquid nitrogen. Some clinics keep those frozen eggs stored at an onsite lab, but in most cases they are shipped to an offsite facility. As soon as you’re ready to use them, they can be safely shipped back. 

In either case, the frozen eggs' care doesn't end at storage. They are monitored regularly to ensure the liquid nitrogen levels remain constant, and the facility's temperature control and security systems are working correctly. A well-maintained facility prioritizes meticulous record-keeping, tracking the storage duration and any other pertinent details about each egg. 

Cofertility members can take advantage of our partnership with TMRW Life Sciences, a fertility technology company that has developed the world's first automated solution for storing and managing frozen eggs and embryos. 

TMRW's technology platform digitally identifies, tracks, monitors and stores patients' frozen eggs and embryos with safety, accuracy, efficiency and transparency. TMRW's platform sets a new standard of care by reducing potential points of failure by 94% compared with manual systems.

So what is TMRW doing differently? 

• Digital labeling - instead of handwritten labels, TMRW uses digital labeling and RFID tracking. With this tracking system, clinics always know exactly where your eggs and embryos are and can easily find them when you’re ready to use them.
• Automated management - instead of relying on manual processes, TMRW has a new fully-automated digital system that helps eliminate 94% of potential failure points
• Real-time inventory - TMRW has gone the extra mile by creating a 24/7 cloud-based monitoring system with real-time inventory updates to provide new levels of safety, transparency, and peace of mind. 
• Active monitoring - TMRW provides 24/7 digital monitoring (thousands of daily checks!) and expert human oversight to identify potential issues before they become a problem.

Will my eggs survive the thaw?

Several factors can impact the success of egg thawing, including your age when the eggs are frozen, the number and quality of the eggs, the technique used to freeze the eggs, and the quality of the clinic’s laboratory. 

The quality of the eggs is also a crucial factor in egg thawing. Good quality eggs have a higher chance of survival and fertilization. However, even with good quality eggs, there is no guarantee of success, and the process may need to be repeated to achieve pregnancy.

If and when you decide to use them

When you decide the time is right to use your frozen eggs, they are thawed in the lab using a warming solution. 

But keep in mind that thawing is just the first part. The eggs will then need to be fertilized with sperm and grown into embryos. The surviving eggs are then fertilized using a process called intracytoplasmic sperm injection (ICSI), where a single sperm is injected directly into each egg.

After fertilization, the resulting embryos are monitored for a few days as they begin to develop. The most viable embryos are then transferred to your uterus in a procedure similar to a pap smear. If successful, the embryo implants in your uterus and grows, leading to pregnancy.

Generally, the younger you are when freezing your eggs, the better the chances of success. Eggs frozen in your late 20s or early 30s have a higher chance of survival and successful fertilization compared to those frozen in your late 30s or 40s.

If you decide NOT to use them

What if, down the line, you decide not to use your eggs, or you have more than you need? 

One study of egg freezing patients at UCSF found that 89% believed they would be glad they froze their eggs, even if they never used them to conceive a child. So if you don't end up needing your frozen eggs down the line, there are a few options for what to do with them.

• Keep them in storage. Most storage facilities offer long-term storage options (our partnership with TMRW includes plans up to 10-years long), allowing you to keep your eggs frozen for as many years as  necessary. This may be a good option if you're not yet ready to use the eggs but want to keep them as a backup plan.
• Donate the eggs to someone else who may need them. Egg donation is a process of donating eggs to another person or couple who needs them, such as LGBTQ+ families or those suffering from infertility. This can be a wonderful gift for those who may not be able to have a child otherwise. If you go through our Split program, you will have already been cleared as a donor and can easily donate these additional eggs. If you’re not part of the Split program but think you may be interested in this down the line, talk to your doctor as they may be able to do some additional donor-related screening during your egg freezing process. 
• Dispose of them.  If you decide that you no longer need your frozen eggs and don't want to continue storing them or donate them, simply request that they are disposed of by the clinic or storage facility.
• Donate to science. Many research studies rely on donated eggs to investigate new techniques and treatments for infertility. Ask your clinic if this is an option.

Emotional considerations

Aside from the practical aspects, it's important to acknowledge the emotional journey involved in egg freezing. It's normal to feel a mix of emotions – relief, hope, anxiety, or even sadness. Know that these feelings are common and valid. Don't hesitate to seek support, be it from a trusted friend, family member, a professional counselor, or the Cofertility community.

Summing it up

The journey of your eggs from freezing to potential future use is complex and exciting, underscored by sophisticated science and meticulous care. Deciding to freeze your eggs can be an empowering choice, giving you autonomy over your fertility and future family planning. Knowing what happens to your eggs after freezing them can provide comfort and clarity as you navigate your fertility journey.

In the end, egg freezing is an investment in your future, offering an opportunity to expand your family when the time is right for you. It's a testament to the advancements in reproductive science and a tool for you to take control of your fertility. Trust in the process, seek support when needed, and above all, know that your choices are valid, and your feelings are heard. After all, the journey to parenthood, in whatever form it takes, is a voyage of hope, love, and extraordinary potential.

If you’re ready to freeze your eggs, we’re here to help. Reach out or learn more about our Freeze program.

Read more:

• Egg Freezing: How Long Can My Eggs Be Stored?
• Egg Freezing Thaw Rates
• When Should I Freeze My Eggs?

Thanks to developments in medical technology, a growing emphasis on reproductive autonomy (thank goodness), and opportunities like our Split program, egg freezing is now more accessible than ever. However, the financial commitment doesn’t stop with the initial freezing process. A key consideration is the long-term cost of storing frozen eggs, an important component of financial planning for those pursuing egg freezing.

Understanding frozen egg storage costs can help you make informed decisions about your reproductive future. Whether you're considering freezing your eggs now or managing storage costs from a previous cycle, knowing the financial breakdown can ensure better long-term planning. After all, these days, frozen eggs can be stored indefinitely. 

Below, we explore the typical expenses associated with frozen egg storage and the factors that can affect these costs. One note: this article contains figures provided at the time of writing, and they may all be subject to change over time. 

Average costs of egg storage

Retrieving and freezing your eggs is just the beginning. Once frozen, your eggs will need to be stored, and the cost of egg storage can vary widely depending on the facility, location, and other factors. Here's a general breakdown of what you can expect to pay for storing your frozen eggs:

Annual egg storage fees

On average, storage fees for frozen eggs can range from $500 to $1,000 per year. These fees cover the ongoing maintenance of your eggs at sub-zero temperatures in a cryobank or fertility clinic. Some clinics in major metropolitan areas may charge upwards of $1,200 per year, while smaller clinics or cryobanks in less populated regions may offer more affordable rates.

Many facilities offer discounts for pre-paying for several years of storage upfront. These long-term storage plans may reduce the yearly cost to around $400 to $700 per year, depending on the contract length. Typically, clinics offer 3-to 10-year prepaid storage options, with deeper discounts for more extended commitments.

You also have the option of working directly with a long-term storage facility. Cofertility partners with TMRW Life Sciences, which offer our members – regardless of where they froze their eggs – discounted long-term storage rates (more on that below!).

Transportation costs 

In addition to the annual fees, there may be other costs to consider, such as the cost to transport your eggs to a different facility or clinic. Moving frozen eggs between storage facilities, either across town or internationally, can cost up to $1,500, depending on the logistics involved.

Factors affecting egg storage costs

Several factors influence the total cost of storing your eggs. Here's a look at the most common elements that determine frozen egg storage pricing:

Geographic location

Like most medical or cryopreservation services, egg storage costs vary significantly depending on the location of the cryobank or fertility clinic. Facilities in major cities tend to charge more due to higher operational costs. In contrast, clinics in smaller towns or rural areas may offer more affordable rates. Women freezing their eggs in cities like New York, San Francisco, or Los Angeles may see storage fees at the higher end of the spectrum, while facilities in less densely populated areas might provide more budget-friendly options.

Type of egg storage facility

‍The type of facility storing your eggs also plays a role in the cost. Fertility clinics, dedicated cryobanks, and hospital-affiliated storage facilities all have different pricing structures. Fertility clinics often charge more for egg storage, as they may outsource the service to third-party cryobanks and tack on additional fees. Dedicated cryobanks, such as TMRW Life Sciences, may offer better deals, especially if they specialize in long-term storage. Hospitals with fertility departments may provide storage, but the costs can vary significantly depending on their resources and expertise in fertility preservation.

Storage duration

The length of time you store your eggs also impacts the total cost. As mentioned earlier, many facilities offer discounts for long-term storage commitments, with prepaid plans that can save you money over time. If you expect to store your eggs for five years or more, opting for a multi-year plan may be a smart financial decision.

Additional services

Some clinics or cryobanks charge extra fees for services like annual maintenance, insurance, or egg retrieval for future use. These services can add hundreds of dollars to your overall storage costs, so it's essential to ask about all potential fees upfront when choosing a storage facility.

One note: check with your clinic to see if the number of eggs stored (or number of cycles) will impact your annual storage fees. It generally doesn’t, but worth confirming directly. 

Tips for managing egg storage costs

While egg storage costs can add up over time, there are several strategies you can use to manage these expenses more effectively:

Shop around

Don’t assume you must store your eggs at the same fertility clinic where they were frozen. In fact, many fertility clinics send eggs to third-party cryobanks for storage and may charge an additional fee for this service. It's worth researching local cryobanks and comparing their rates directly, as this could save you money. If you’re interested in learning more about storage with TMRW, Cofertilty’s team can get you connected directly. 

Consider bundled packages

Some clinics offer bundled packages that include both the egg freezing process and a certain number of years of storage at a discounted rate. If you're just beginning the egg freezing process, ask about package deals that could save you money on storage costs in the long run.

Explore financial assistance options

There are several grants, financing programs, and payment plans designed to help women cover the costs of egg freezing and storage. For example, organizations like Baby Quest and the Cade Foundation offer grants for fertility preservation, while some clinics may provide in-house financing options. We’ve actually got a whole article about various ways to pay for egg freezing, which you can find here. 

Our programs

We offer our members ways to help reduce or eliminate storage costs altogether. With our Split program, where you freeze your eggs for free when donating half of the mature eggs retrieved, storage is entirely free for 10 years. Alternatively, the Keep program allows you to freeze all of your eggs for your own future use, while still accessing discounted rates for storage through Cofertility’s partnership with TMRW Life Sciences. 

Cofertility’s partnership with TMRW Life Sciences

We’ve partnered with TMRW Life Sciences to offer our community exclusive storage rates, helping to save thousands on frozen egg storage costs. TMRW’s state-of-the-art facility provides unparalleled transparency, safety, and accountability, using advanced digital labeling and RFID tracking technology to monitor the storage of your frozen eggs continuously. 

With TMRW, you also have constant access to data about your eggs, so you can feel confident that they are being stored securely and safely.

Summing it up

Egg storage costs are an often overlooked part of the overall financial planning process when considering egg freezing. From annual storage fees to potential transportation costs, it's important to understand all the factors that contribute to the total cost of egg freezing. 

By exploring different storage options, taking advantage of bundled packages, and considering innovative opportunities like our Split and Keep programs, you can manage your egg storage costs more effectively while safeguarding your reproductive future.

To learn more about our Split program and see if you qualify, click here!

Read More:

• Egg Freezing: How Long Can My Eggs Be Stored?
• What Happens to My Eggs After Egg Freezing?
• What Happens to My Frozen Eggs if I Never Use Them?
• How to Pay for Egg Freezing